Abstract Eine Hemmung der Cyclooxygenase‐Reaktion bei Prostaglandinbildung des Rattennierenmarks in vitro ist durch verschiedene Flavonoide mit o‐Dihydroxystrukturen möglich. Diese einer Brenzcatechin‐Anordnung im Molekül besitzen ausgeprägte Radikalfängereigenschaften für Peroxid‐Anion‐Radikale. Dagegen können einige und Phenolderivate, die starke O 2 −• ‐Radikalfänger sind, Prostaglandinsynthetase aber auch aktivieren oder unbeeinflußt lassen. Korrelation zwischen den Beeinflussung...

Induction thermography is a non‐contacting, non‐destructive evaluation method with wide range of applications. A deeper understanding the detectability cracks requires fundamental knowledge about induced current density distribution in component under test. calculation provides information how much flowing at which location component, crack disturbs density, heat produced and diffuses to surface. The heating process depends on type crack. On one hand there are can be detected mainly by...

Prediction-based decision-making systems are becoming increasingly prevalent in various domains. Previous studies have demonstrated that such vulnerable to runaway feedback loops, e.g., when police repeatedly sent back the same neighborhoods regardless of actual rate criminal activity, which exacerbate existing biases. In practice, automated decisions dynamic effects on system itself – ML literature is sometimes referred as performative predictions can perpetuate over time, making it...

The effect of blocking the formation endothelium-derived relaxing factor/nitric oxide (EDNO) on pressure-dependent renin release (RR) was studied in six conscious foxhounds with chronically implanted catheters abdominal aorta and renal vein. Renal blood flow (RBF) measured an ultrasonic transit-time flowmeter. RR determined by multiplying venous-arterial plasma activity difference flow. artery pressure (RAP) reduced steps a pneumatic occluder placed around suprarenal aorta. A dose 1,000 mg...

Algorithmic predictions are promising for insurance companies to develop personalized risk models determining premiums. In this context, issues of fairness, discrimination, and social injustice might arise: Algorithms estimating the based on personal data may be biased towards specific groups, leading systematic disadvantages those groups. Personalized premiums thus lead discrimination injustice. It is well known from many application fields that such biases occur frequently naturally when...

In six chronically instrumented, conscious dogs the hypothesis was tested that release of endothelium-derived relaxing factor (EDRF) is important for autoregulation renal blood flow (RBF) and glomerular filtration rate (GFR). RBF measured by a Transonic flowmeter. Renal perfusion pressure servo-controlled an aortic cuff. EDRF synthesis inhibited NG-nitro-L-arginine methyl ester (L-NAME, 50 mg/kg iv). L-NAME increased mean systemic (30 mmHg) decreased heart (-40 beats/min), but it left GFR...

Many new services for mobile radio networks rely on a precise location of the terminal. Especially in urban environments, multipath propagation leads to very complex scenarios without line-of-sight between and different base stations. In these situations, technique based simple delay evaluations and/or GPS is not accurate enough or applicable. this paper, database correlation method positioning terminals presented which yields results environments. The approach models utilized planning...

Nowadays, Machine Learning (ML) systems are widely used in various businesses and increasingly being adopted to make decisions that can significantly impact people's lives. However, these decision-making rely on data-driven learning, which poses a risk of propagating the bias embedded data. Despite attempts by algorithmic fairness community outline different types data algorithms, there is still limited understanding how biases relate ML-based systems. In addition, efforts mitigate...

Abstract Due to its salient properties, mobile agent technology has received rapidly growing attention over the last few years. Many developments ofmobile systems are under way in both academic and industrial environments. MOLE is one of first that been developed Java language; version came out 1995. Since then constantly improved, provides a stable environment for development usage agents area distributed applications. Furthermore, it used extensively our research at University Stuttgart....

Binary decision making classifiers are not fair by default. Fairness requirements an additional element to the rationale, which is typically driven maximizing some utility function. In that sense, algorithmic fairness can be formulated as a constrained optimization problem. This paper contributes discussion on how implement fairness, focusing concepts of positive predictive value (PPV) parity, false omission rate (FOR) and sufficiency (which combines former two).

Advertising funds a number of services that play major role in our everyday online experiences, from social networking, to maps, search, and news. As the power reach advertising platforms grow, so do concerns about potential for discrimination associated with targeted advertising. However, despite ever-improving ability measure describe instances unfair distribution high-stakes ads—such as employment, housing, or credit—we lack tools model predict extent which alternative systems could...

1. Spontaneously occurring haemodynamic variations within 4 h affecting renal blood flow (RBF) were compared with externally induced short changes of artery pressure (RAP) in conscious resting dogs. 2. In all animals which RAP was servo‐controlled (n = 6), perfect autoregulation RBF observed. 3. recordings spontaneous 9), certain combinations and occurred remarkably frequently as indicated by three‐dimensional frequency distributions. 4. Cluster analysis demonstrated significant differences...

The effects of blocking endothelium-derived relaxing factor (EDRF) on 24-h blood pressure and heart rate (HR) were examined in six conscious freely moving foxhounds. hypothesis tested was that shear stress-dependent EDRF release acts as a physiological buffer. Telemetry recordings obtained before after the administration false substrate for synthesis NG-nitro-L-arginine (L-NNA, 16.5 +/- 2 mg/kg body wt iv). In response to L-NNA, mean arterial (MAP) increased from 116 5 134 mmHg (P less than...

Ensuring fairness of prediction-based decision making is based on statistical group criteria. Which one these criteria the morally most appropriate depends context, and its choice requires an ethical analysis. In this paper, we present a step-by-step procedure integrating three elements: (a) framework for moral assessment what means in given recently proposed general principle "Fair equality chances" (FEC) (b) mapping assessment's results to established criteria, (c) method thus-defined into...