Qin Lian

ORCID: 0000-0003-2028-2706
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About
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Research Areas
  • Additive Manufacturing and 3D Printing Technologies
  • Bone Tissue Engineering Materials
  • 3D Printing in Biomedical Research
  • Electrospun Nanofibers in Biomedical Applications
  • Osteoarthritis Treatment and Mechanisms
  • Orthopaedic implants and arthroplasty
  • Total Knee Arthroplasty Outcomes
  • Dental Implant Techniques and Outcomes
  • Periodontal Regeneration and Treatments
  • Anatomy and Medical Technology
  • Dental materials and restorations
  • Knee injuries and reconstruction techniques
  • Orthopedic Infections and Treatments
  • Organic Light-Emitting Diodes Research
  • Cancer, Lipids, and Metabolism
  • Inflammatory Biomarkers in Disease Prognosis
  • Muscle activation and electromyography studies
  • Wound Healing and Treatments
  • Tissue Engineering and Regenerative Medicine
  • Organic Electronics and Photovoltaics
  • Luminescence and Fluorescent Materials
  • Photopolymerization techniques and applications
  • Innovations in Concrete and Construction Materials
  • Silk-based biomaterials and applications
  • Lanthanide and Transition Metal Complexes

Guangxi Medical University
2024-2025

Xi'an Jiaotong University
2014-2024

Guangxi University of Science and Technology
2024

Lanzhou Jiaotong University
2024

National Medical Products Administration
2024

General Administration of Sport of China
2023-2024

Guangzhou Sport University
2023-2024

Shandong First Medical University
2023

Shandong Tumor Hospital
2023

Xinjiang Medical University
2022-2023

Abstract The drawbacks of traditional bone-defect treatments have prompted the exploration bone tissue engineering. This study aimed to explore suitable β-tricalcium phosphate (β-TCP) granules for regeneration and identify an efficient method establish β-TCP-based osteo-regenerators. β-TCP with diameters 1 mm 1–2.5 were evaluated in vitro . superior osteogenic properties used vivo bioreactors, referred as osteo-regenerators, which fabricated using two different methods. Improved...

10.1038/srep23367 article EN cc-by Scientific Reports 2016-03-22

Purpose The purpose of this paper is to fabricate and characterize osteochondral beta‐tricalcium phosphate/collagen scaffold with bio‐inspired design by ceramic stereolithography (CSL) gel casting. Design/methodology/approach Histological analysis was applied explore the morphological characteristics transitional structure between bone cartilage. acquired data were used biomimetic biphasic scaffolds, which include phase, cartilage their structure. engineered scaffolds fabricated from...

10.1108/13552541211193511 article EN Rapid Prototyping Journal 2012-01-13

Purpose This paper aims to develop an additive manufacturing technique for complex zirconia ceramic dental bridges. Design/methodology/approach To carry out this study, a bridge model was obtained by three-dimensional reverse engineering, and light-curable suspension formulated. Zirconia bridges were manufactured stereolithography then treated vacuum freeze drying, infiltration sintering. The optimal scanning speed determined according the shape precision comparison. Then, characteristics of...

10.1108/rpj-09-2016-0144 article EN Rapid Prototyping Journal 2017-11-30

Organ-on-a-chip has emerged as a powerful platform with widespread applications in biomedical engineering, such pathology studies and drug screening. However, the fabrication of organ-on-a-chip is still challenging task due to its complexity. For an integrated organ-on-a-chip, it may contain four key elements, i.e., microfluidic chip, live cells/microtissues that are cultured this components for stimulus loading mature microtissues, sensors results readout. Recently, bioprinting been used...

10.1063/1.4982945 article EN Biomicrofluidics 2017-05-01

Abstract Acute lung injury (ALI) is a life threatening disease in critically ill patients, and characterized by excessive reactive oxygen species (ROS) inflammatory factors levels the lung. Multiple evidences suggest that nanozyme with diversified catalytic capabilities plays vital role this fatal injury. At present, we developed novel class of polydopamine (PDA) coated cerium dioxide (CeO 2 ) (Ce@P) acts as potent ROS scavenger for scavenging intracellular suppressing responses against ALI....

10.1186/s12951-024-02570-w article EN cc-by Journal of Nanobiotechnology 2024-06-08

Purpose This paper aims to describe computer‐aided design and rapid prototyping (RP) systems for the preoperative planning fabrication of custom‐made implant. Design/methodology/approach A patient with mandible defect underwent reconstruction using 3D models patient's skull are generated based on computed tomography image data. After evaluation reconstructed image, it was identified that some bone fragment moved due missing segment. During implant process, correct position defined geometry...

10.1108/13552540910925027 article EN Rapid Prototyping Journal 2009-01-16

Increasing evidences show that subchondral bone may play a significant role in the repair or progression of cartilage damage situ. However, exact change during osteochondral is still poorly understood. In this paper, biphasic composite scaffolds were fabricated by 3D printing technology using PEG hydrogel and β-TCP ceramic then implanted rabbit trochlea within critical size defect model. Animals euthanized at 1, 2, 4, 8, 16, 24, 52 weeks after implantation. Histological results showed...

10.1155/2014/746138 article EN cc-by BioMed Research International 2014-01-01

Lower extremity musculoskeletal computational models play an important role in predicting joint forces and muscle activation simultaneously are valuable for investigating functional outcomes of the implants. However, current total knee replacement rarely consider bearing surface geometry implant. Therefore, these lack detailed information about contact loading motion which factors evaluating clinical performances. This study extended a rigid multi-body dynamics simulation lower model to...

10.1177/0954411914537476 article EN Proceedings of the Institution of Mechanical Engineers Part H Journal of Engineering in Medicine 2014-05-30

The association between sleep-related disorders and cardiovascular diseases (CVDs) remains controversial lacks epidemiological evidence in the general population. We investigated whether are related to CVDs a large, nationally representative, diverse sample of American adults.Data were collected from National Health Nutrition Examination Survey (NHANES) 2005-2008. Logistic regression was performed explore associations with prevalence total specific CVDs. Stratified subgroup analysis exclude...

10.3389/fcvm.2022.954238 article EN cc-by Frontiers in Cardiovascular Medicine 2022-08-04

<title>Abstract</title> Recent developments in artificial intelligence have ushered a new era of language models, with capabilities that are rapidly advancing the frontiers technology and communication. The present research conducts detailed comparative analysis three prominent large models—ChatGPT, Mistral, Llama—utilizing Hugging Face platform to benchmark their performance across multiple dimensions, including computational efficiency, linguistic accuracy, ethical alignment. Results...

10.21203/rs.3.rs-4376810/v1 preprint EN cc-by Research Square (Research Square) 2024-05-07

In-situ printing is a promising injury repair technique that can be directly applied during surgical operations. This paper features potential in-situ platform based on small-scale robotic arm with micro-sized dispenser valve. A double-light-source curing method was to print poly(ethylene glycol) diacrylate (PEGDA) 20% (weight/volume) ratio and the entire process controlled automatically by computer interface where droplet diameter, time, mechanical properties were measured essential...

10.3390/app7010073 article EN cc-by Applied Sciences 2017-01-11

Mal-rotation of the components in total knee arthorplasty (TKA) is a major cause postoperative complications, with an increased propensity for implant loosening or wear leading to revision. A musculoskeletal multi-body dynamics model was used perform parametric study effects rotational mal-alignments TKA on loading under simulated walking gait. The contact forces were found be more sensitive variations varus-valgus rotation both tibial and femoral internal-external component TKA....

10.1002/jor.22908 article EN Journal of Orthopaedic Research® 2015-03-27
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