- Health Systems, Economic Evaluations, Quality of Life
- Healthcare Policy and Management
- Global Health Care Issues
- Healthcare cost, quality, practices
- Metallurgy and Cultural Artifacts
- Fiscal Policy and Economic Growth
- Labor Movements and Unions
- Global Public Health Policies and Epidemiology
- Economic Theory and Institutions
- Corporate Taxation and Avoidance
- Structural Behavior of Reinforced Concrete
- Aviation Industry Analysis and Trends
- Education Systems and Policy
- Employment and Welfare Studies
- Structural Engineering and Vibration Analysis
- Antibiotic Resistance in Bacteria
- Multiple Myeloma Research and Treatments
- Economic and Environmental Valuation
- Structural Load-Bearing Analysis
- Second Language Learning and Teaching
- European and International Law Studies
- European Political History Analysis
- Cancer therapeutics and mechanisms
- European Monetary and Fiscal Policies
- Neuroendocrine regulation and behavior
Los Alamos National Laboratory
2024
Loughborough University
2024
NHS Grampian
2024
University of the West of Scotland
2023-2024
Cardiff and Vale University Health Board
2023
University of Derby
2020-2022
Milliman (United States)
2021
Manado State University
2021
Australian Institute of Business
2014-2016
ACT Government
2014
<h3>Abstract</h3> <b>Objective:</b> To measure the health of a representative sample population United Kingdom by using EuroQoL EQ-5D questionnaire. <b>Design</b>: Stratified random general aged 18 and over living in community. <b>Setting</b>: Kingdom. <b>Subjects:</b> 3395 people resident <b>Main outcome measures:</b> Average values for mobility, self care, usual activities, pain or discomfort, anxiety depression. <b>Results:</b> One three respondents reported problems with discomfort....
An important consideration when establishing priorities in health care is the likely effects that alternative allocations of resources will have on health-related quality-of-life (HRQoL). This paper reports a large-scale national study elicited relative valuations attached by general public to different states (defined HRQoL terms). Health state were derived using time trade-off (TTO) method. The data from 3395 respondents highly consistent, suggesting it feasible use TTO method elicit...
Chiral compounds account for 25% of all agrochemical used commercially and 26% the total value world market. However, those sold in single isomer form contribute only 7% to market despite many potential advantages terms regulatory, intellectual property marketing benefits. Limited access chiral raw materials economic synthesis routes are key reasons why isomers less common than they might be. The development more will encourage capitalise on their advantages.
Many clinicians believe that allowing costs to influence clinical decisions is unethical. They are mistaken in this belief, because it cannot be ethical ignore the adverse consequences upon others of you make, which what 'costs' represent. There are, however, some important issues deciding count, and how count them. But these dilemmas equally strong with respect benefits them, expose ethically untenable assumptions about such widely-used criteria as survival rates. One advantages systematic...
Two hundred children were followed from birth through 2 years of age with nasopharyngeal cultures to determine the normal colonization pattern nontypeable Haemophilus infiuenzae. Forty-four percent colonized on one or more occasions; acquisition rate was greatest in first year. Monthly prevalence rates 11%. Colonization initial strain persisted 1–5 months (median, 2). Children carried 1 predominant at a time but became up 7 different strains (mean, 2.2). single for ⩽2 produced greater...
Abstract Logical inconsistencies in survey respondents' valuations of hypothetical health states – represented by the EQ‐5D, for example present a conundrum as to whether or not their responses ought be included estimating social ‘tariffs’. A ‘logical inconsistency’ occurs when state that ‘in logical terms’ is unambiguously less severe than another assigned lower value. Excluding such defensible on data quality grounds but puts at risk representativeness estimated tariff, given it meant...
Isolation can affect our well-being negatively. To prevent the spread of infection COVID-19, many workers, including university lecturers, are required to work from home. In order maintain high levels and team cohesion, academics at University Derby Online Learning initiated a virtual huddle briefly socialise check on their colleagues’ every morning. This piece field notes reports context (COVID-19 in United Kingdom), details this morning socialization, first-hand experience attending...
Mycobacterium tuberculosis survives and replicates in macrophages, where it is exposed to reactive oxygen nitrogen species that damage DNA. In this study, we investigated the roles of UvrA UvrD1, thought be parts nucleotide excision repair pathway M. tuberculosis. Strains which uvrD1 was inactivated either alone or conjunction with uvrA were constructed. Inactivation resulted a small colony phenotype, although growth liquid culture not significantly affected. The sensitivity mutant strains...
Abstract Background: Lung cancer remains the leading cause of cancer-related death in United States. Precision oncology is revolutionizing early-stage non-small cell lung (NSCLC) treatment, showing promising results improving outcomes. Utilization molecular residual disease (MRD) testing has potential to improve outcomes by detecting relapse ahead clinical presentation. Currently, up 38% patients are ineligible for tumor-informed MRD tests due insufficient tissue, often resulting from risks...