A5056703425- Photochemistry and Electron Transfer Studies
- Free Radicals and Antioxidants
- Photochromic and Fluorescence Chemistry
- Chemical Reaction Mechanisms
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Synthesis and Reactions of Organic Compounds
- Spectroscopy and Quantum Chemical Studies
- Molecular Sensors and Ion Detection
- Electrochemical Analysis and Applications
- Synthesis and Characterization of Heterocyclic Compounds
- Porphyrin and Phthalocyanine Chemistry
- Chemical Synthesis and Reactions
- Chemical Synthesis and Analysis
- Synthesis and Biological Evaluation
- Analytical Chemistry and Chromatography
- Inorganic and Organometallic Chemistry
- Organic Chemistry Cycloaddition Reactions
- Chemical and Physical Properties in Aqueous Solutions
- Surfactants and Colloidal Systems
- Oxidative Organic Chemistry Reactions
- Crystallography and molecular interactions
- Fluorine in Organic Chemistry
- Synthesis of Organic Compounds
- Molecular spectroscopy and chirality
Universidad de Santiago de Chile
2016-2025
Universidad Bernardo O'Higgins
2014-2024
Instituto de Química y Fisicoquímica Biológicas
2016-2019
University of O'Higgins
2016
Universidade Federal de Santa Catarina
1988-2001
Universidade de São Paulo
1989
An analysis of the antibacterial activities 15 terpenoids, eleven which werepreviously described by us and four were extracted from literature, suggested twostructural requirements for activity these related compounds: a hydrophobic moiety,consisting substituted decalin skeleton, hydrophilic region possessing onehydrogen-bond-donor group. These structural are responsible an optimalinsertion compounds into cell membranes, as resultsof docking some model phospholipid bilayer.
We have been able to "tune" the electrocatalytic activity of iron phthalocyanine (FePc) and hexadodecachlorophthalocyanine (16(Cl)FePc) for oxygen reduction reaction (ORR) by manipulating "pull effect" pyridinium molecules axially bounded complexes (FePcs). These axial ligands play both role molecular anchors also wires. The affect reactivity Fe metal center in phthalocyanine. originates from positive charge located on core. explored influence core positions (Up or Down), two structural...
We have prepared self-assembled monolayers (SAMs) of 4-aminothiophenol (4-ATP) and 1-(4-mercaptophenyl)-2,6-diphenyl-4-(4-pyridyl)pyridinium tetrafluoroborate (MDPP) functionalized with iron phthalocyanine (FePc) copper (CuPc) adsorbed on gold (111) electrodes. The catalytic activity these SAMs/MPc was examined for the reduction O2 in aqueous solutions compared to that bare coated directly preadsorbed MPc molecules. Scanning tunneling microscopy (STM) studies confirm functionalization 4-ATP...
Abstract An attempt has been made in order to unify the three types of solvatochromisms (negative, positive and inverted) phenolate betaine dyes by a working model which describes them as particular cases general behavior. The model, based on calculation (gas phase) chemical hardness donor acceptor fragments, was applied 56 examples from literature. As result, investigated compounds were grouped according sum hardnesses their (non‐interacting) this being larger for negative, intermediate an...
A series of chalcones and aurones were synthesized evaluated in vitro as monoamine oxidase inhibitors (MAOi). Our results show that aurones, which had not been previously reported MAOi, are MAO-B inhibitors. Thus, both families inhibited selectively the B isoform MAO micromolar range, offering novel scaffolds for design new potent The main structural requirements their activity characterized with aid 3D-QSAR docking studies.
A re-examination of cuticular components Heliotropium filifolium allowed the isolation four new compounds: 3'-hydroxy-2',2',6'-trimethyl-3H-spiro[1-benzo-furan-2,1'-cyclohexane]-5-carboxylic acid(2), methyl 3'-acetyloxy-2',2',6'-trimethyl-3H-spiro[1-benzofuran-2,1'-cyclohexane]-5-carboxylate (3), 3'-isopentanoyloxy-2',2',6'-trimethyl-3H-spiro[1-benzofuran-2,1'-cyclohexane]-5-carboxylate (4) and 3'-benzoyloxy-2',2',6'-trimethyl-3H-spiro[1-benzofuran-2,1'-cyclohexane]-5-carboxylate...
Six dyes with N,N-dimethylaminophenyl and 4-nitrophenyl or 2,4-dinitrophenyl groups in their molecular structures were prepared characterized. These compounds have different conjugated bridges (CC, CN, NN) connecting the electron-donor electron-acceptor groups. All are solvatochromic, reverse solvatochromism occurring. The solvatochromic band observed each spectrum for is due to a π ➔ π* transition, of an intramolecular charge transfer nature, which occurs from group molecules, reinforced...
The solvatochromic behaviour of merocyanines can be interpreted and predicted by consideration their molecular structure with the aid a model that regards all kinds solvatochromism as particular cases generalized reverse behaviour. This reversal is shown to consistent cyanine-limit model, another independent approach relates merocyanine its Both models are validated experimental data from literature 21 variable structure. Copyright © 2016 John Wiley & Sons, Ltd.
Ultrasound irradiation promoted the cyclocondensation of β-keto esters and amidines in good to excellent yields form sixteen highly substituted 4-pyrimidinols. Tosylation these compounds, another ultrasound-promoted conversion, formed 4-pyrimidyl tosylates high yields. The use developed protocol as an alternative route 4-arylpyrimidines was illustrated with three examples Suzuki–Miyaura cross-coupling prepared phenylboronic acid.
The ability of polarizable continuum models (PCM) to simulate nonspecific solvent effects (dipolarity and polarizability) was evaluated by calculating the transition energies 1,1,10,10-tetrabutyldecanonaene (ttbp9) 2-
ABSTRACT The 1 H‐ and 13 C‐NMR spectra of three substituted N‐ (4‐hydroxyphenyl)pyridinium perchlorates, precursors solvatochromic 4‐pyridiniophenolate betaines, were recorded in deuterated acetone, dimethylsulfoxide, acetonitrile, their spectral behavior these solvents was analyzed as evidence the solute–solvent interactions present solution. effect increasing orthogonality between phenolic pyridinium fragments clearly evident from obtained spectra, thus shedding light on ground‐state...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTKinetic behavior of cetyltrimethylammonium hydroxide. The dehydrochlorination 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane and some its derivativesEduardo Stadler, Dino Zanette, Marcos C. Rezende, Faruk NomeCite this: J. Phys. Chem. 1984, 88, 9, 1892–1896Publication Date (Print):April 1, 1984Publication History Published online1 May 2002Published inissue 1 April...
Seven new 2,4,6-triarylpyrimidines were synthesized and their solvatofluorochromism investigated in 12 solvents an aqueous micellar solution of reduced Triton X-100. A multiparametric analysis emission band showed that the solvent dipolarity basicity mainly responsible for solvatofluorochromism, which arose from internal charge-transfer a donor fragment to pyrimidine acceptor, confirmed by theoretical calculations. In system, quenching fluorescence addition derivatives...
The solvatochromic shifts of the two isomeric title betaines 4 and 5, built up from unsubstituted pyridinio acceptor phenoxide donor fragments, were recorded in twelve solvents data compared with results semi-empirical (AM1) ab initio (HF/6-311G B3LYP/6-311G) calculations.
A. R. Katritzky, U. Gruntz, D. H. Kenny, M. C. Rezende and Sheikh, J. Chem. Soc., Perkin Trans. 1, 1979, 430 DOI: 10.1039/P19790000430
Five new solvatochromic 2,6-diaryl-4-ferrocenylethenylpyrimidines were synthesized and their spectral variations in solution investigated twenty-seven solvents of variable polarity.