- Advanced biosensing and bioanalysis techniques
- SARS-CoV-2 and COVID-19 Research
- SARS-CoV-2 detection and testing
- Liver Disease Diagnosis and Treatment
- Biosensors and Analytical Detection
- Biotin and Related Studies
- Animal Virus Infections Studies
- COVID-19 Clinical Research Studies
- Multiple Sclerosis Research Studies
- Systemic Lupus Erythematosus Research
- Peripheral Neuropathies and Disorders
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Viral Infections and Immunology Research
- HIV Research and Treatment
- Liver Disease and Transplantation
- Advanced Malware Detection Techniques
- Hepatocellular Carcinoma Treatment and Prognosis
Clinique Saint Pierre
2022
Cliniques Universitaires Saint-Luc
2018-2020
UCLouvain
2018-2020
Rapid antigen detection (RAD) tests are commonly used for the diagnosis of SARS-CoV-2 infections. However, with continuous emergence new variants concern (VOC), presenting various mutations potentially affecting nucleocapsid protein, analytical performances these assays should be frequently reevaluated. One hundred and twenty samples were selected tested both RT-qPCR six commercial RAD that sold in Belgian pharmacies. Of these, direct whole-genome sequencing identified strains present 116...
The diagnostic of SARS-CoV-2 infection relies on reverse transcriptase polymerase chain reactions (RT-PCRs) performed nasopharyngeal (NP) swabs. Nevertheless, false-negative results can be obtained with inadequate sampling procedures, making the use other biological matrices worthy investigation. This study aims to evaluate kinetics serum N antigens in severe and non-severe patients compare clinical performance antigenic assays NP RT-PCR. Ninety were included monitored for several days....
The detection of cerebrospinal fluid (CSF)-specific IgG oligoclonal bands (OCB) by isoelectric focusing (IEF) is widely used to help diagnose inflammatory neurological disorders (IND), including multiple sclerosis. However, the quantification free light chains (FLC) increasingly evaluated as a surrogate method determine presence an intrathecal process. objective this study was evaluate diagnostic performance kappa (κ) FLC measurement in comparison with OCB IEF.We measured serum and CSF κFLCs...
Rapid antigen detection tests (RAD) are commonly used for the diagnosis of SARS-CoV-2 infections. However, with continuous emergence new variants concern (VOC) presenting various mutations potentially affecting nucleocapsid protein, analytical performances these assays should be frequently reevaluated. One-hundred and twenty samples were selected tested both RT-qPCR five commercial RAD sold in Belgian pharmacies. Of these, direct whole genome sequencing identified strains present 116...
(1) Background: High immunosuppressive regimen in lung transplant recipients (LTRs) hampers the immune response to vaccination. We prospectively investigated immunogenicity of heterologous ChAdOx1 nCoV-19-BNT162b2 mRNA vaccination an LTR cohort. (2) Methods: Forty-nine COVID-19 naïve LTRs received a two-dose nCoV-19 vaccine. A subset 32 patients booster dose BNT162b2 vaccine 18 weeks after second dose. (3) Results: Two-doses induced poor with 7.2% seropositivity at day 180 and low...
Our team of diabetologist is challenged by the case a 41 year-old woman with recurrent hypoglycaemic episodes. Her clinical background was complex with, among others, neuroendocrine tumor, nonalcoholic steatohepatitis and an adrenal insufficiency; these conditions require exploration several potential causes. After excluding endogenous etiology, factitious hypoglycemia quicky suspected clinicians. However, venous samples showed normal insulinemia moderately decreased C-peptide....