Małgorzata Główka

ORCID: 0000-0003-2048-3778
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About
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Research Areas
  • Viral gastroenteritis research and epidemiology
  • SARS-CoV-2 and COVID-19 Research
  • SARS-CoV-2 detection and testing
  • vaccines and immunoinformatics approaches
  • Animal Virus Infections Studies
  • Bacillus and Francisella bacterial research
  • Respiratory viral infections research
  • Microbial Natural Products and Biosynthesis
  • Protein purification and stability
  • Biosensors and Analytical Detection
  • Microbial Metabolic Engineering and Bioproduction
  • Peroxisome Proliferator-Activated Receptors
  • Hepatitis B Virus Studies
  • Inhalation and Respiratory Drug Delivery
  • RNA Interference and Gene Delivery
  • Virus-based gene therapy research

National Institute of Public Health
2018-2023

Wojskowy Instytut Higieny i Epidemiologii
2018

Abstract Most point-of-care tests (POCT) use swabs for sampling and/or applying a sample on the test. A variety of differing in tip materials is commercially available. Different have different chemical and physical characteristics which might influence specimen collection release. We investigated properties various types used clinical diagnostics with focusing two kinds analytes, DNA proteins, are most often targets POCT. As model samples we diphtheria toxoid NIBSC 69/017 investigating...

10.1186/s13568-020-00978-9 article EN cc-by AMB Express 2020-03-12

Abstract The machinery of antibiotic production by Penicillium chrysogenum PQ-96 is composed co-located cytosolic and peroxisomal enzymes the penicillin G biosynthesis pathway. Pexophagy exocytosis should be currently considered as an alternative for secretion from mycelial cells. Penicillin overproduction a cellular detoxification process, protecting mycelium toxicity precursor. 1. Introduction. 2. Peroxisomal functions biosynthesis. 3. Immunoelectron microscopyof isopenicillin N synthase....

10.21307/pm-2019.58.1.080 article EN cc-by-nc-nd Postępy Mikrobiologii - Advancements of Microbiology 2019-01-01

Vaccines adsorbed on aluminum adjuvants irreversibly lose potency after freezing and their safety is affected. To prevent the administration of such vaccines, World Health Organization developed Shake Test designed to determine whether vaccines have been frozen or not. However, difficult time-consuming when routinely conducted at place vaccination. In this study, a modified shake test for prequalification potentially was elaborated.Vaccines used in Polish Immunization Schedule were...

10.7774/cevr.2022.11.2.155 article EN cc-by-nc Clinical and Experimental Vaccine Research 2022-01-01
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