A5062357413- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Hemoglobinopathies and Related Disorders
- Iron Metabolism and Disorders
- Systemic Lupus Erythematosus Research
- Parvovirus B19 Infection Studies
- Animal Virus Infections Studies
- T-cell and B-cell Immunology
- Pancreatitis Pathology and Treatment
- Dermatological and COVID-19 studies
- COVID-19 epidemiological studies
- COVID-19 and Mental Health
- SARS-CoV-2 detection and testing
- Mosquito-borne diseases and control
- Plant Virus Research Studies
- Lymphoma Diagnosis and Treatment
- Metabolism and Genetic Disorders
- Monoclonal and Polyclonal Antibodies Research
- Vector-borne infectious diseases
- Neonatal Health and Biochemistry
- Biosensors and Analytical Detection
- Diabetes and associated disorders
- Blood groups and transfusion
- Viral Infections and Vectors
- Vascular Malformations and Hemangiomas
All India Institute of Medical Sciences Raipur
2020-2025
Health and Human Services Agency
2021-2025
All India Institute of Medical Sciences Bhubaneswar
2025
Marymount University
2024
Imperial College Healthcare NHS Trust
2023
Abstract Between November 2021 and February 2022, SARS-CoV-2 Delta Omicron variants co-circulated in the United States, allowing for co-infections possible recombination events. We sequenced 29,719 positive samples during this period analyzed presence fraction of reads supporting mutations specific to either or variant. identified 18 co-infections, one which displayed evidence a low Delta-Omicron recombinant viral population. also two independent cases infection by virus, where 100% RNA came...
Background Nephrotic syndrome (NS) is a common renal ailment among children, typically manifesting as relapsing-remitting pattern. Most of the cases are managed on an outpatient basis, but subset patients experience complications, e.g., acute kidney injury (AKI). Although historically more prevalent in secondary NS, AKI now occurring increasingly children with idiopathic NS. However, literature this population consists case reports and retrospective studies, particularly from India, so study...
Diabetic peripheral neuropathy is a common complication of diabetes mellitus that has dire outcomes, affecting the economic profile country. Despite multifactorial background pathogenesis this disease, mechanism underlying still unclear. Endothelial damage new determinant pathogenesis, with endocan as potential biomarker for endothelial dysfunction in diabetic patients. In cross-sectional study, 49 patients and 48 without neuropathy, biomarkers such endocan, hs-CRP, vitamin D, lipid profiles...
Abstract Background Quality healthcare is dependent on continuous input and feedback. The California Department of Public Health (CDPH) requires that all general acute care hospital (GACH) report healthcare-associated infections (HAI) annually. Comparisons current facility-specific standardized infection ratios (SIRs) to the National Healthcare Safety Network (NHSN) 2015 SIR baseline provide designations whether a facility statistically significantly better, worse, or average are displayed...
The study is aimed to investigate the metabolic alterations and changes in biochemical parameters associated with extended mask.It was a prospective comparative conducted on 129 participants comprised of 37 healthy controls 92 health care workers using different kind masks like, cloth mask, surgical N95-FFR/PPE. Two samples day-1 day-10 were collected for analysis blood gas parameters, serum hypoxia-inducible factor-α (HIF-α), erythropoietin (EPO).Oxygen saturation percentage (sO2) 72.68 (P...
Background The evaluation of the effectiveness vaccines (ChAdOx1-nCOV; Covishield and BBV-152; Covaxin) against coronavirus disease 2019 (COVID-19) is necessary to assess their efficacy. Because most antibodies that neutralize are directed receptor binding domain within spike protein virus, these serve as markers for viral neutralizers and, in turn, vaccine response. present study aimed evaluate anti-neutralizing antibody (receptor (RBD)) immunoglobulin G2 (IgG2) titers following completion...
Introduction An array of routinely accessible serum biomarkers was assessed to explore their overall impact on severity and mortality in coronavirus disease 2019. Materials Methods A retrospective analysis 1,233 adults conducted. The study groups comprised 127 nonsurvivors 1,106 survivors. Data for demographic details, clinical presentations, laboratory reports were recorded from the medical record section. predictors analyzed influence mortality. Results mean (+ standard deviation) age...
Between November 2021 and February 2022, SARS-CoV-2 Delta Omicron variants co-circulated in the United States, allowing for co-infections possible recombination events. We sequenced 29,719 positive samples during this period analyzed presence fraction of reads supporting mutations specific to either or variant. identified 18 co-infections, one which displayed evidence a low Delta-Omicron recombinant viral population. also two independent cases infection by virus, where 100% RNA came from...
Background: The prevalence of sickle cell disease (SCD) in western Odisha is 9.1 % which a quite high figure if one looks at the morbidity and mortality out it. In sickle-cell disease, low-oxygen tension promotes RBC sickling repeated episodes sickling damages the membrane makes it rigid. Free radical increased irreversible by damaging Several newly emerging biological markers have potentiality to be utilized deciding degree oxidative stress and disease severity. Aims & Objective: We...
Dear Editor, In the journal's September 2020 issue, commentary “Behera KK, Hota D, Mahapatra A. COVID 19 and diabetes: An endocrinologist's perspective. J Family Med Prim Care 2020;9:4512-5“[1] briefly summarizes pathogenesis of increased mortality desirable actions by physicians in diabetic patients with COVID-19 infection. The authors have stressed role prevailing chronic inflammation inviting infections diabetes. synthesis advanced glycated end products pro-inflammatory cytokines high...
Summary The maturation of genomic surveillance in the past decade has enabled tracking emergence and spread epidemics at an unprecedented level. During COVID-19 pandemic, for example, data revealed that local varied considerably frequency SARS-CoV-2 lineage importation persistence, likely due to a combination restrictions changing connectivity. Here, we show are driven by regional transmission, including across international boundaries, but can become increasingly connected distant locations...
Background: Impaired immune status due to altered T-cell response in sickle cell disease (SCD) might provide substantial insight into activity SCD patients. Materials & methods: A total of 30 healthy control, 20 patients a crisis state and 38 steady were evaluated for subsets. Results: significant decrease CD8+ (p = 0.012) CD8+45RA-197+ 0.015) T-cells observed among Naive (45RA+197+; p < 0.01) elevated effector (RA-197-) central memory (RA-197+) grossly reduced the state. Negative regression...
Background Unless a cutoff level of the parameters newborn screening (NBS) is defined, test's results would end in high recall rates and apprehensive parents. The study aimed to establish healthy term newborns. Materials methods was retrospective observational data analysis on cohort 1158 newborns who underwent NBS our institute. percentile distribution computed 99th value considered new cutoff. For lower values, such as neonatal glucose 6-phosphate dehydrogenase (nG6PD) biotinidase (nBIOT),...
Objectives: To detect pattern of dyslipidemia in patients SLE and clarify the correlation between lipid profile with disease activity, inflammatory factors, cytokines. Materials Methods: Blood collected from 65 30 healthy controls measured Th-17, IL-17, IL-10 by flow cytometer. Statistical analysis: The relationship various parameters was analyzed stepwise logistic regression used to assess predictors dyslipidemia. Results: unique high activity a significant decline density lipoprotein (HDL)...
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by autoantibody production and immune complex deposition in various organs. The pathogenesis of SLE multifactorial, involving genetic, hormonal, environmental, factors. Interleukin-10 (IL-10) a pleiotropic cytokine produced cells has conflicting roles inflammation.