- Curcumin's Biomedical Applications
- Advanced biosensing and bioanalysis techniques
- 3D Printing in Biomedical Research
- Polysaccharides and Plant Cell Walls
- Enzyme Production and Characterization
- DNA and Nucleic Acid Chemistry
- Innovative Microfluidic and Catalytic Techniques Innovation
- Biofuel production and bioconversion
- Advanced Drug Delivery Systems
- Advancements in Transdermal Drug Delivery
- Surfactants and Colloidal Systems
- Polyoxometalates: Synthesis and Applications
- Enzyme Catalysis and Immobilization
- Hydrogels: synthesis, properties, applications
- Pickering emulsions and particle stabilization
- Phytochemicals and Antioxidant Activities
- Food Chemistry and Fat Analysis
- Microbial metabolism and enzyme function
- Polymer Surface Interaction Studies
- Lipid Membrane Structure and Behavior
- Micro and Nano Robotics
- Nuclear Materials and Properties
- Polysaccharides Composition and Applications
- Bee Products Chemical Analysis
- Nuclear reactor physics and engineering
University of Chemistry and Technology, Prague
2014-2025
Centre National de la Recherche Scientifique
1999-2006
Charles University
1997-2004
Czech Academy of Sciences, Institute of Physics
1997-2004
Sorbonne Université
1999-2004
Food Research Institute Prague
1963-1977
Central Research Institute
1963
Research Institute for Labour and Social Affairs
1958
The assembly of cell wall components, cellulose and xyloglucan (XG), was investigated at the atomistic scale using molecular dynamics simulations. A model a crystal corresponding to allomorph Ibeta exhibiting flexible complex external morphology employed mimic microfibril. molecules considered were three typical basic repeat units, differing only in size one lateral chain. All XG fragments adsorb nonspecifically onto fiber; multiple arrangements are equally probable, every surface capable...
(1) Background: Huntington’s disease (HD) is rare incurable hereditary neurodegenerative disorder caused by CAG repeat expansion in the gene coding for protein huntingtin (HTT). Mutated (mHTT) undergoes fragmentation and accumulation, affecting cellular functions leading to neuronal cell death. Porcine models of HD are used preclinical testing currently emerging modifying therapies. Such therapies aimed at reducing mHTT expression, postpone onset, slow down progression, point out need...
The reversible, temperature-dependent change in the permeability of a phospholipid bilayer has been used for controlling diffusion rate encapsulated molecular payload from liposomes. Liposomes were preloaded with fluorescent dye and immobilized calcium alginate hydrogel microparticles that also contained iron oxide nanoparticles. composite produced by drop-on-demand inkjet method. ability nanoparticles to locally dissipate heat upon exposure radio-frequency (RF) alternating magnetic field...
Single–particle analysis using inductively coupled plasma mass spectrometry offers a new tool for the characterisation of inorganic nanoparticles. Its development is connected with generations ultrafast spectrometers. This work concerned thorough investigation parameters affecting quality Ag nanoparticles, i.e., nanoparticle stability, transport efficiency and sensitivity determination. The short-term stability nanoparticles in demineralised water can be prolonged to at least 7 h by addition...
ABSTRACT Anammox bacteria wield an energy‐efficient nitrogen metabolism enveloped in anammoxosome organelle composed of unique ladderane lipids. Thus, waste anammox biomass seems to be attractive target for the isolation ladderanes and subsequent production artificial vesicles drug delivery. This study proposed a novel method isolate ladderane‐rich anammoxosomes from aggregate mixed culture Ca . Brocadia sapporoensis. Compared conventional protocols, protocol was simplified by omitting...
A colloidal system able to act as a miniature reactor for on-demand release of reactive payloads has been demonstrated. The is based on submicrometer aggregates consisting anionic liposomes that storage reservoirs the reactants, superparamagnetic iron oxide nanoparticles (SPIONs) enable magnetic positioning in space and controlled reactants from by radiofrequency stimulation, an oppositely charged polyelectrolyte (poly-l-lysine) keeps constituent elements within at defined ratio. kinetics...
Our results have shown a positive effect of mixture GPs and curcumin on Nrf2/ARE activation. Also, there was an observable increase the expression superoxide dismutase 1 (by mixture) heme oxygenase composites).