- Electrochemical Analysis and Applications
- Advanced biosensing and bioanalysis techniques
- Analytical Chemistry and Sensors
- Biosensors and Analytical Detection
- Electrochemical sensors and biosensors
- Advanced Sensor and Energy Harvesting Materials
- Force Microscopy Techniques and Applications
- Nanoparticle-Based Drug Delivery
- Vestibular and auditory disorders
- Advanced Cellulose Research Studies
- Conducting polymers and applications
- Carbon Nanotubes in Composites
- SARS-CoV-2 detection and testing
- Electrocatalysts for Energy Conversion
- Advanced Biosensing Techniques and Applications
- Advanced Photocatalysis Techniques
- Neuroinflammation and Neurodegeneration Mechanisms
- Electrospun Nanofibers in Biomedical Applications
- Nanocomposite Films for Food Packaging
- Graphene research and applications
- Neuroscience and Neural Engineering
- Advanced Nanomaterials in Catalysis
- RNA Interference and Gene Delivery
- Cellular Mechanics and Interactions
- Spectroscopy and Quantum Chemical Studies
Xi'an Jiaotong University
2016-2025
National Clinical Research Center for Digestive Diseases
2025
Peking University
2003-2025
Beijing University of Chemical Technology
2025
Union Hospital
2025
Huazhong University of Science and Technology
2025
Fuwai Yunnan Cardiovascular Hospital
2025
Anhui University of Traditional Chinese Medicine
2024
Shanghai Changzheng Hospital
2019-2024
Wuhan University
2023-2024
Abstract Skin interstitial fluid (ISF) holds great potential as a highly desirable sample resource for point‐of‐care testing (POCT), where the key is to effectively collect target biomarkers from ISF. Hydrogel microneedle patch has promise ISF extraction. However, it challenging recover extracted skin in hydrogel patches an easy‐administrated, fast, and bulky instrument‐free manner. Herein, made of polyvinyl alcohol (PVA) chitosan (CS) POCT based on developed. The phase transition property...
Abstract The ever‐growing overlap between stretchable electronic devices and wearable healthcare applications is igniting the discovery of novel biocompatible skin‐like materials for human‐friendly electronics fabrication. Amongst all potential candidates, hydrogels with excellent biocompatibility mechanical features close to human tissues are constituting a promising troop realizing healthcare‐oriented functionalities. In this work, based on hydrogels, simple paradigm prototype an embedded...
Abstract Detection of biomarkers associated with body conditions provides in‐depth healthcare information and benefits to disease management, where the key challenge is develop a minimally invasive platform ability directly detect multiple in fluid. Dermal tattoo biosensor holds potential simultaneously health‐related skin interstitial fluid because features minimal invasion, easy operation, equipment‐free result reading. Herein, colorimetric dermal fabricated by four‐area segmented...
A dextran‐based self‐healing hydrogel is prepared by reversible Diels–Alder reaction under physiological conditions. Cytocompatible fulvene‐modified dextran as main polymer chains and dichloromaleic‐acid‐modified poly(ethylene glycol) cross‐linkers are used. Both macro‐ microscopic observation well the rheological recovery test confirm property of dextran‐l‐poly(ethylene hydrogels (“l” means “linked‐by”). In addition, scanning electrochemical microscopy used to qualitatively quantitatively...
Lateral flow assays (LFAs) as rapid analytical techniques promise to be widely used in point-of-care (POC) diagnostics because of their affordability and simplicity. However, LFAs still suffer from low sensitivity detection various biomarkers, e.g., nucleic acids. In this study, we developed a simple general one-step signal amplification strategy, which employed oligonucleotide-linked gold nanoparticle (AuNP) aggregates enhance the acid lateral (NALF) assays. Using sequence human...
Driven by high throughput next generation sequencing technologies and the pressing need to decipher cancer genomes, computational approaches for detecting somatic single nucleotide variants (sSNVs) have undergone dramatic improvements during past 2 years. The recently developed tools typically compare a tumor sample directly with matched normal at each variant locus in order increase accuracy of sSNV calling. These programs also address detection sSNVs low allele frequencies, allowing study...
Composites of chitosan chloride and bacterial cellulose were successfully prepared by in situ method. cellulose/chitosan pristine investigated means scanning electron microscope, atomic force Fourier transform infrared spectroscopy, thermogravimetric analysis, X-ray diffraction, bacteriostatic test. The crystallization was interfered weakened the included growth media, resulting lower crystallinity index thermal stability. And interaction between two polymers is verified gravimetric...
The emerging demand for cost‐effective, easily accessible, and rapid prototyping electronics fabrication calls novel techniques to design manufacture electronic components devices wearable functional sensing, on‐skin medical monitoring, body‐worn energy conversion. Inspired by daily hand‐writing, innovative ubiquitously available pens can be employed write conductive patterns on multiple substrates; such a low‐cost, fast, user‐friendly direct writing paradigm has recently aroused remarkable...
A versatile method for spatially modulating hydrogel stiffness was proposed. The locally stiffened presented tunable strain-shielding ability and thus aided to electronic components integration wearable electronics.
Flexible wearable devices have proven to be emerging tools for motion monitoring, personal healthcare, and rehabilitation training. The development of a multifunctional, flexible sensor the integration sensors smart chip signal reading transmission play critical role in building device. In this work, glove based on multiwalled carbon nanotubes/poly(dimethylsiloxane) (MWNTs/PDMS) fibers is developed gesture temperature recognition. First, well-tunable, stretchable, thermal-sensitive...
The physical confinement of cell microenvironment could enhance the invasive capability and drug resistance cancer cells. However, due to lack in vitro experimental platform mimic both stiffness tumor microenvironment, underlying mechanism remains elusive. Here, we developed a hydrogel-based microchannel with independently tunable channel width physiological range. We found that migration speed is influenced by synergistic effect width. In addition, mesenchymal-amoeboid transition has strong...