A5069565670- Cutaneous Melanoma Detection and Management
- Nonmelanoma Skin Cancer Studies
- Breast Cancer Treatment Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Colorectal Cancer Surgical Treatments
- Breast Lesions and Carcinomas
- Colorectal and Anal Carcinomas
- Surgical site infection prevention
- COVID-19 and healthcare impacts
- Immunotherapy and Immune Responses
- Breast Implant and Reconstruction
- Cutaneous lymphoproliferative disorders research
- Sarcoma Diagnosis and Treatment
- Vascular Malformations and Hemangiomas
- Melanoma and MAPK Pathways
- Central Venous Catheters and Hemodialysis
- Reconstructive Surgery and Microvascular Techniques
- Vascular Tumors and Angiosarcomas
- Cardiac tumors and thrombi
- Polyomavirus and related diseases
- CAR-T cell therapy research
- Healthcare Operations and Scheduling Optimization
- Gastric Cancer Management and Outcomes
- Cell Image Analysis Techniques
- Vascular Procedures and Complications
Ospedale Policlinico San Martino
2012-2022
Istituti di Ricovero e Cura a Carattere Scientifico
2012-2020
Regione Liguria
2020
Society of Surgical Oncology
2019
University of Genoa
1993-2017
Alleanza Contro il Cancro
1997-2014
National Cancer Research Institute
2005-2012
Background and Objectives The increasing use of peripherally inserted central venous catheters (PICCs) for chemotherapy has led to the observation an elevated risk complications failures. This study investigates PICC failures in cancer patients. Methods A prospective was conducted at a single institution on 291 placement chemotherapy. primary outcome failure. Results Median follow‐up 119 days. occurred 72 patients (24.7%) with removal 44 (15.1%). Reasons were upper extremity deep thrombosis...
Open colorectal cancer (CRC) surgery induces severe and prolonged postoperative pain. The optimal method of analgesia in CRC has not been established. We evaluated the efficacy preperitoneal continuous wound infusion (CWI) ropivacaine for after open a multicenter randomized controlled trial.Candidates randomly received CWI or epidural (CEI) with 0.2% 10 mL/h 48 hours surgery. Fifty-three patients were allocated to each group. All patient-controlled IV morphine analgesia.Over 72-hour period...
Background and objectives: The increasing use of arm totally implantable vascular access devices for breast cancer patients who require chemotherapy has led to a greater risk complications failures and, in particular, upper extremity deep vein thrombosis. This study aims investigate the outcomes peripherally inserted central catheter-PORT technique patients. Methods: is an evolution standard arm-totally device implant based on guided ultrasound venous proximal third limb with subsequent...
Abstract Background Laparoscopic cholecystectomy is considered the gold standard for treatment of gallbladder lithiasis; nevertheless, incidence bile duct injuries (BDI) still high (0.3–0.8%) compared to open (0.2%). In 1995, Strasberg introduced "Critical View Safety" (CVS) reduce risk BDI. Despite its widespread use, scientific evidence supporting this technique prevent BDI controversial. Methods Between March 2017 and 2019, data patients submitted laparoscopic in 30 Italian surgical...
Electrochemotherapy (ECT) is technique for local control of skin metastasis. This study primarily aimed at assessing the clinical activity ECT in a prospective cohort patients, and evaluating association between primary tumor histology, number metastatic lesions size deposits objective response rate.Thirty-nine patients with metastases from melanoma other tumors underwent intravenous bleomycin palliative intent. No serious adverse events (SAE) or CTC grade 3 4 were observed. Overall rate...
Recent studies have demonstrated the possibility of identifying sentinel lymph node (sN) as a reliable predictor axillary status in both cutaneous melanoma and breast cancer. However, some important issues need further definition: (1) optimization technique for intraoperative detection sN; (2) predictive value sN regards status, (3) reliability histology sN. We report our experience mapping patients with Stage I–II cancer, aim assessing: feasibility lymphatic combined approach (vital blue...
Abstract Background and Objectives A randomised clinical trial was performed in patients undergoing radical surgery for rectal cancer to compare the efficacy toxicity of adjuvant postoperative radiation therapy (RT) sequential RT chemotherapy (CT) with 5‐fluorouracil (5‐FU) plus levamisole (LEV). The primary end point overall survival (OS); secondary points were disease‐free (DFS), rate loco‐regional recurrence, treatment‐related toxicity; final results this are reported. Methods Patients...
Objectives Two-hundred eighteen patients with TNM stage II-III resectable rectal cancer, enrolled into a randomized clinical trial, were assessed for efficacy and toxicity of adjuvant postoperative radiation therapy (RT) vs. those combined RT chemotherapy (CT), 5-fluorouracil (5-FU) plus levamisole. End points overall survival, disease-free the rate loco-regional recurrence, treatment-related toxicity. Methods Patients in arm I underwent (50 Gy) daily fractions 2 Gy, 5 days/week weeks. II...
This study investigates the incidence of post-operative complications and risk factors sentinel lymph node biopsy (SLNB) in melanoma patients.A retrospective cohort was conducted at a single cancer institution on 408 consecutive SLNBs.Fifty-five occurred 39 (9.5%) patients included: wound infection 24 (5.9%), seroma lymphorrhea 15 (3.7%), dehiscence seven (1.7%), lymphocele six (1.5%) others three (0.7%). Univariate analysis failed to identify possible (i.e. gender, age, region, number...