Many risk factors for hip fractures have been suggested but not evaluated in a comprehensive prospective study.

This report describes changes in eight areas of functioning after a hip fracture, identifies the point at which maximal levels recovery are reached each area, and evaluates sequence recuperation across multiple functional domains. METHODS. Community-residing fracture patients (n = 674) admitted to hospitals Baltimore, Maryland, 1990-1991 were followed prospectively for 2 years from time hospitalization. Eight function (i.e., upper lower extremity physical instrumental activities daily...

OBJECTIVES: To examine the association between strength, function, lean mass, muscle density, and risk of hospitalization. DESIGN: Prospective cohort study. SETTING: Two U.S. clinical centers. PARTICIPANTS: Adults aged 70 to 80 (N=3,011) from Health, Aging Body Composition Study. MEASUREMENTS: Measurements were grip knee extension walking speed, chair stand pace. Thigh computed tomography scans assessed area density (a proxy for fat infiltration). Hospitalizations confirmed by local review...

Abstract It is uncertain whether or how rapidly elderly women continue to lose bone with advancing age. To determine rates of change in mass at the hip and calcaneus compare these among estrogen users nonusers, we prospectively measured mineral density (BMD) total its four subregions (mean ± SD, 3.55 0.29 years between examinations) 5.69 0.33 5698 community-dwelling white aged 65 older baseline examination. The rate decline BMD steadily increased from 2.5 mg/cm2/year (95% confidence interval...

Objective : To determine the factors associated with impaired function in older women. Design Cross‐sectional analysis of baseline data collected for a multicenter, prospective study risk osteoporotic fractures. Setting Four clinical centers Portland, Oregon, Minneapolis, Minnesota, Baltimore, Maryland, and Monongahela Valley, Pennsylvania. Participants A total 9,704 ambulatory, non‐black women, aged 65 years older, recruited from population‐based listings. Measurements Independent...

OBJECTIVE: The purpose of this study was to estimate the excess mortality attributable hip fracture. METHODS: 6-year survival rate community-dwelling White female fracture patients aged 70 years and older entering one seven hospitals from 1984 1986 (n = 578) compared with that respondents interviewed in for Longitudinal Study on Aging 3773). RESULTS: After age, education, comorbidity, functional impairment were controlled, differential between two groups accumulated an among 9 deaths per 100...

Objective: To determine the anthropometric, historical, and lifestyle factors associated with bone mineral density (BMD) of spine proximal femur in older women. Design: Cross-sectional analyses. Setting: Four clinical centers Baltimore, Maryland; Minneapolis, Minnesota; Portland, Oregon; Monongahela Valley, Pennsylvania. Participants: 7963 ambulatory, nonblack women 65 years age or older. Measurements: Medical history was obtained by questionnaire interview, physical anthropometric data were...

Results from previous studies of reproductive factors and bone density have been conflicting; some demonstrate a beneficial effect, but others show detrimental effect on density. The present study investigates the association parity, lactation, menstruation with radial in 2230 white women, 65 years age older. Bone was assessed by single-photon absorptiometry. Linear multiple regression utilized to determine if were associated number births, duration menstrual bleeding, at menarche,...

Objectives. Estimate and compare the proportion of cancer patients with cachexia using different definitions from available clinical data. Methods. Electronic medical records were examined to estimate 4 definitions: (1) ICD-9 diagnostic code 799.4 (cachexia), (2) diagnosis cachexia, anorexia, abnormal weight loss, or feeding difficulties, (3) prescription for megestrol acetate, oxandrolone, somatropin, dronabinol, (4) >/=5% loss. Patients stomach, pancreas, lung, colon/rectum, head/neck,...

Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of death in Korea. According to a report published by Statistics Korea 2014, cerebrovascular and were major/leading causes mortality. However, it more difficult identify prevalence incidence than mortality owing lack national-level statistics. Few studies have examined ASCVD its risk factors since 2012. This study aimed estimate using national claims data. We conducted retrospective analysis data Health Insurance Review...

To evaluate the incremental cost in year after hip fracture.Prospective cohort study.Baltimore, Maryland.759 community dwelling older patients who sustained a fracture and participated Baltimore Hip Fracture Study.Resource use for direct medical care, formal nonmedical informal care 6 months before was estimated from interviews with or proxy respondents. Costs 1993 dollars were by multiplying resources times national unit estimates.The annualized costs ranged between $18,523 $20,928. The...

Background. More than 220,000 persons 65 years and older fracture a hip every year in the United States. Although fractures have been considered as single, homogeneous condition, there are two major anatomic types of proximal femoral fractures: intertrochanteric neck. The present study's objective was to determine if different patient characteristics sequelae. Methods. A prospective study 923 elderly patients admitted seven Baltimore hospitals for between 1984 1986. Results. Patients with...

Background. Hip fracture in elderly persons has a serious impact on long-term physical function. This study determines the change muscle strength and mass after hip fracture, associations between these changes mobility recovery.

Prostaglandin inhibition by aspirin or nonsteroidal anti-inflammatory drug (NSAIDs) may inhibit bone loss and preserve mineral density (BMD) in vitro animal models. The effect of these agents on BMD fracture risk postmenopausal women unknown. We assessed the factors for osteoporosis use NSAIDs 7786 white over age 65. Axial was measured at same time, fractures were prospectively documented subsequent 4 years follow-up. In age-adjusted analyses, daily associated with a 2.3-5.8% increase hip...

OBJECTIVE—The American Diabetes Association (ADA) lists seven symptoms of diabetes; however, it is not known how specific these are for initial diagnosis type 2 diabetes. The Study to Help Improve Early evaluation and management risk factors Leading (SHIELD) examined prevalence ADA their association with diabetes diagnosis. RESEARCH DESIGN AND METHODS—SHIELD a 5-year observational study individuals or at Following an screening phase, follow-up questionnaires were mailed stratified random...

Tumor necrosis factor (TNF)-blockers are approved for use in several immune-related conditions, but treatment patterns, such as switching between TNF blockers or restarting after a gap therapy, not clearly established. This analysis examined blocker patterns within the first year initiating with etanercept, adalimumab, infliximab patients rheumatoid arthritis, psoriasis, psoriatic ankylosing spondylitis.Administrative claims data from MarketScan® Commercial Claims and Encounters Database...

To empirically identify groupings of strength, physical performance, adiposity, and lean mass test how such these interrelated measures may relate to disability risk.

Health-related quality of life studies among adults with type 2 diabetes mellitus, using the EQ-5D, have been short term and not assessed change over years. This study in health status health-related 5 years individuals without diabetes.Respondents to US Study Help Improve Early evaluation management risk factors Leading Diabetes (SHIELD) completed EuroQol-5D (EQ-5D) at baseline (2004) later (2009). Visual analog scale (VAS) score index were computed year 5, was measured for mellitus (T2DM)...

European clinical guidelines recommend a low-density lipoprotein cholesterol (LDL-C) goal of < 70 mg/dL. Statin use varies and past studies suggest low rates real-world attainment. This study describes LDL-C attainment among atherosclerotic CV disease (ASCVD) patients with various utilization patterns moderate- or high-intensity statins in routine care.This retrospective cohort used electronic medical records data from the QuintilesIMS® Disease Analyzer (> 2 million individuals annually) to...

Secondary hyperparathyroidism (SHPT) is common in patients with chronic kidney disease (CKD). Many recommendations the Kidney Disease Improving Global Outcomes (KDIGO) CKD-mineral and bone disorder guidelines are supported by modest evidence predate approval of newer agents. Therefore, an expert panel defined consensus SHPT practice patterns United States real-world context from nephrology community. Ten US healthcare providers one patient participated a modified Delphi method comprising...