Background: Retinal ganglion cell (RGC) loss is crucial in eye diseases like glaucoma. Axon damage and dendritic degeneration precede death, detectable within optical coherence tomography (OCT) resolution, indicating their correlation with neuronal degeneration. The purpose of this study to evaluate the changes early retinal Methods: detection axotomised explants was completed six C57BL/6J mice. OCT images were acquired up 120 min from enucleation. A grey-level co-occurrence-based texture...

Optical coherence tomography (OCT) is an imaging technique based on interferometry of backscattered lights from materials and biological samples. For the quantitative evaluation OCT system, artificial optical samples or phantoms are commonly used. They mimic structure tissues can provide a quality standard for comparison within across devices. Phantoms contain medium matrix scattering particles dimension range target structures such as retina. The aim was to determine if changes in speckle...

The human ability to perceive the polarization state of blue light through a phenomenon known as Haidinger's brush is important, due its link ocular diseases like macular degeneration, but utility limited by lack interpretable outcome measures. This study uses structured create polarization-defined entoptic images that vary purely along radial direction, with apparent sizes can be directly measured and interpreted. methods presented here offer another dimension exploration complement...

The ability to perceive polarization-related entoptic phenomena arises from the dichroism of macular pigments held in Henle’s fiber layer retina and can be inhibited by retinal diseases, such as age-related degeneration, which alters structure macula. Structured light tools enable direct probing pigment density through perception polarization-dependent patterns. Here, we directly measure visual angle an pattern created illumination with a structured state task that is insensitive corneal...

Optical coherence tomography (OCT) phantoms are essential tools for calibrating imaging systems, validating diagnostic algorithms, and bridging technological advancements with clinical applications. This review explores the development application of materials used in OCT phantoms, emphasising their optical, mechanical, biochemical fidelity to biological tissues. Gelatin-based (n = 1.35) offer controllable absorbance scattering, penetration depths (PDs) 500–2000 µm scattering coefficients...

To characterize the optical density of circularly oriented macular pigment (MP) in human retina, as a quantification health, Psychophysical discrimination tests were performed on subjects using structured light-induced entoptic phenomena. Central exclusions used to determine visual extents stimuli with varying spatiotemporal frequencies. A model was developed describe action MP, and map perceived sizes. The experimental results provided validation for computational model, showing good...

Integrating optical coherence tomography (OCT) into the pre-surgical stage of cataract management holds significant clinical and economic potential, particularly in low-to-middle-income countries like Kazakhstan. This study aimed to evaluate these impacts by prospectively recruiting 124 patients, aged 70±8 years, from two ophthalmology surgical centers Almaty, Patients undergoing phacoemulsification cataracts with monofocal intraocular lens (IOL) implantation between January December 2022...

Introduction: Cataract is a prevalent eye condition that affects millions of individuals worldwide, leading to visual impairment and reduced quality life. surgery the most effective treatment, but post-surgical complications can arise, impacting success intervention. Optical coherence tomography (OCT) has emerged as valuable imaging technique for evaluating these complications, manual interpretation OCT images time-consuming subjective.Objective: In this study, we aimed assess performance...

To analyse the effect of state screening program for glaucoma, funded by Kazakhstan State programs health care system “Salamatty Kazakhstan” (2011–2015) and “Densaulyk” (2016–2019), on glaucoma diagnosis. This study involved 1,620,658 men women 40–70 years age. includes measures intraocular pressure (IOP) corneal thickness. Data incidence were retrieved from statistics dataset. Studies vulnerable age groups ophthalmologists’ availabilities assessed, correlations with detection determined....

The ability to perceive polarization-related entoptic phenomena arises from the dichroism of macular pigments held in Henle's fiber layer retina and can be inhibited by retinal diseases such as age-related degeneration, which alter structure macula. Structured light tools enable direct probing pigment density through perception polarization-dependent patterns. Here, we directly measure visual angle an pattern created illumination with a structured state task that is insensitive corneal...

The incorporation of structured light techniques into vision science has enabled more selective probes polarization related entoptic phenomena. Diverse sets stimuli have become accessible in which the spatially dependant optical properties can be rapidly controlled and manipulated. For example, past studies with human perception dealt that appear to vary azimuthally. This is mainly due constraint typically available degree freedom manipulate phase shift rotates perceived pattern around a...

Abstract Purpose There is uncertainty about the effect of increased neonatal protein intake on neurodevelopmental outcomes following preterm birth. The aim this study was to assess a change in nutrition protocol at major tertiary intensive care unit intended increase ophthalmic and visual development school‐age children born very preterm. Methods cohort comprised ( n = 128) with birthweight <1500 g or gestational age < 30 weeks Auckland City Hospital before (OldPro group, 55) after...

The macular pigment (MP) in the radially-oriented Henle fibers that surround foveola enables ability to perceive orientation of polarized blue light through an entoptic phenomena known as Haidinger's brush. MP has been linked eye diseases and central field dysfunctions, most notably age-related degeneration (AMD), a globally leading cause irreversible blindness. Recent integration structured techniques into vision science allowed for development more selective versatile probes health provide...

The dichroic macular pigment in the eye acts as a natural radial polarization filter and enables humans to directly perceive polarization-related entoptic phenomena. Linearly polarized blue light induces subtle bowtie-like pattern known Haidinger’s brush central point of vision. clarity shape this perceived are linked health macula, rendering potential diagnostic marker research on early-stage age-related degeneration (AMD) field visual dysfunction. However, due faint nature signal,...

Psychophysical discrimination of structured light (SL) stimuli may be useful in screening for various macular disorders, including degenerative diseases. The circularly-oriented pigment optical density (coMPOD), calculated from the performance SL-induced entoptic phenomena, reveal a novel functional biomarker health. In this study, we investigated potential influence eye dominance and testing order effects on SL-based stimulus perception, factors that potentially sensitivity tests based SL...

Background: There is a lack of research on the clinical characteristics vitreomacular traction (VMT) in Central Asian population, which evaluates visual recovery and macular hole closure outcomes pars plana vitrectomy (PPV) with membrane peel this population. Methods: This long-term prospective cohort study, conducted at Kazakh Eye Research Institute from June 2015 to December 2021 follow-up period until 2022, included 1574 patients (1784 eyes) VMT syndrome. Among eyes, 724 (40.58%) had VMT,...

Abstract Purpose Analysis of the organizational issues diagnosis glaucoma in Kazakhstan and State programs for health care system: “Salamatty Kazakhstan” “Densaulyk”. Methods The state screening was included increased intraocular pressure (IOP) measurement pachymetry, which used corneal thickness examination. Although IOP can be or normal ranges, thin central cornea generally ignored by ophthalmologists. In this regard, indications examination with systemic hypotension during were expanded,...

We investigated texture analysis of optical coherence tomography (OCT) phantom images. Semi-automated classifier, based on principal component (PCA) and support vector machines (SVM), enables classification phantoms with various content medium scatterers.

Macular pigment is thought to underlie entoptic percepts that enable human discrimination of polarized light. Therefore, polarization sensitivity may be a useful probe macular density and the risk future disease. Structured light beams formed through spin coupled orbital angular momentum states exhibit spatially dependent are therefore ideally suited quantify sensitivity. When fixating at center these beams, polarization-defined percept resembling radial spokes observed. Using such...

Целью данной статьи является обзор литературы по оптимизации администрирования диагностики, лечения и профилактики пациентов с катарактой. Для подробного полноценного обзора разнообразными типами исследований их методологиями была использована технология эволюционирующих стандартов синтеза реалистических метанарративных доказательств, или иначе RAMSES. Были проанализированы более 2 000 публикации, из которых 52 манускриптов были добавлены для окончательного анализа в работе. Из-за растущей...