- Chemical Synthesis and Analysis
- Language and Culture
- Glycosylation and Glycoproteins Research
- Machine Learning in Bioinformatics
- Monoclonal and Polyclonal Antibodies Research
- Origins and Evolution of Life
- Advanced Proteomics Techniques and Applications
- Photosynthetic Processes and Mechanisms
- Metabolomics and Mass Spectrometry Studies
- Evolution and Genetic Dynamics
- Metabolism and Genetic Disorders
- vaccines and immunoinformatics approaches
- RNA and protein synthesis mechanisms
- Mass Spectrometry Techniques and Applications
- Genomics and Chromatin Dynamics
- Influenza Virus Research Studies
Poznań University of Technology
2005-2021
Chronic kidney disease (CKD) is characterized by the progressive loss of functional nephrons. Although cardiovascular (CVD) complications and atherosclerosis are leading causes morbidity mortality in CKD, mechanism which progression CVD accelerates remains unclear. To reveal molecular mechanisms associated with linked to we applied a shotgun lipidomics approach fortified standard laboratory analytical methods gas chromatography-mass spectrometry technique on selected lipid components...
Despite years of study, it is still not clear how life emerged from inanimate matter and evolved into the complex forms that we observe today. One most recognized hypotheses for origins life, RNA World hypothesis, assumes was sparked by prebiotic replicating chains. In this paper, address problems caused interplay between hypothetical replicases parasitic species. We consider coexistence parasite RNAs as well impact parasites on further evolution replicases. For these purposes, used...
Abstract Background The lack of a uniform way for qualitative and quantitative evaluation vaccine candidates under development led us to set up standardized scheme efficacy safety evaluation. We developed implemented molecular immunology methods, designed support tools immunization data storage analyses. Such collection can create unique opportunity immunologists analyse delivered from their laboratories. Results GeVaDSs (Genetic Vaccine Decision Support system) an interactive system...
Determining amino acid sequences of protein molecules is one the most important issues in molecular biology. These determine structure and functionality. Unfortunately, direct biochemical methods for reading can be used short only. This reason, which makes peptide assembly algorithms an complement these methods. In this paper, a genetic algorithm solving problem sequence presented. The has been tested computational experiment compared with existing tabu search method same problem. results...