A5016248495- Molecular Sensors and Ion Detection
- Advanced Biosensing Techniques and Applications
- Advanced biosensing and bioanalysis techniques
- Biotin and Related Studies
- Biopolymer Synthesis and Applications
- Mass Spectrometry Techniques and Applications
- bioluminescence and chemiluminescence research
- Click Chemistry and Applications
- Neuroscience and Neuropharmacology Research
The University of Tokyo
2022-2024
We report the development of a chemigenetic fluorescent sodium ion indicator with an affinity optimized for imaging physiologically relevant concentrations in mammalian cells.
Fluorescent imaging sensors based on genetically-encoded and biocompatible proteins have become important tools in medical biological research due to their high spatiotemporal resolution ease of use. Protein engineering has led the development that visualize changes concentration various target molecules/ions, such as calcium ions. In addition, chemigenetic complexes synthetic molecules been gaining momentum recent years. this article, latest trends these are introduced, with focus developed...