A5101823237- NF-κB Signaling Pathways
- Circular RNAs in diseases
- Cytokine Signaling Pathways and Interactions
- Glutathione Transferases and Polymorphisms
- Intensive Care Unit Cognitive Disorders
- Anesthesia and Neurotoxicity Research
- Brain Metastases and Treatment
- MicroRNA in disease regulation
- Cardiovascular Function and Risk Factors
- Melanoma and MAPK Pathways
- Lung Cancer Treatments and Mutations
- Anesthesia and Sedative Agents
- Signaling Pathways in Disease
- Immune Response and Inflammation
- Cancer-related molecular mechanisms research
- interferon and immune responses
- Cardiac Ischemia and Reperfusion
- Heat shock proteins research
- Hepatocellular Carcinoma Treatment and Prognosis
- Electromagnetic Fields and Biological Effects
- Biofuel production and bioconversion
- Sirtuins and Resveratrol in Medicine
- Management of metastatic bone disease
- Ear and Head Tumors
- Genetics, Aging, and Longevity in Model Organisms
Northwest A&F University
2022-2025
Gansu Provincial Hospital
2023-2024
Yantai Laiyang Central Hospital
2021
Shanghai Chest Hospital
2021
Shanghai Jiao Tong University
2021
Jingzhou Maternal and Child Health Hospital
2017-2019
Lanzhou Army General Hospital
2014-2018
Southern Medical University
2004
Nanfang Hospital
2004
University of California, San Diego
1997-2001
Atrial interstitial fibrosis plays a dual role in inducing and maintaining atrial fibrillation (AF). Hypoxia‑inducible factor‑1α (HIF‑1α) has been reported as closely associated with renal, liver pulmonary diseases. However, whether HIF‑1α is involved myocardial fibrosis, the associations between HIF‑1α, transforming growth factor‑β1 (TGF‑β1) matrix metalloproteinase‑9 (MMP‑9) remain unknown. Therefore, this area warrants studying for significance of AF diagnosis treatment. The present study...
To investigate the clinical utility of serum microRNA levels (miR-9-5p and miR-128-3p) in diagnosis prognosis early-stage acute ischemic stroke (AIS).We compared differences miR-9-5p miR-128-3p between patients with AIS healthy individuals (controls). The were quantified using quantitative real-time PCR, association each miRNA was determined receiver operator characteristic curve analysis. predictive value these indices evaluated conjunction that computed tomography findings neuron-specific...
Aged myocardium is more susceptible to ischemia/reperfusion (I/R) injury. Autophagy and apoptosis play important roles in cardiac I/R However, whether resveratrol can reduce the vulnerability of aged by regulating autophagy remains unclear. The present study aimed investigate effect on tolerance injury male mice determine contribution autophagy. We used C57 as our research subjects. hearts were isolated after 6 weeks intragastric administration with subsequently perfused Krebs-Henseleit...
Abstract Oxidative stress plays a pivotal role in the development of diabetic cardiomyopathy (DCM). Previous studies have revealed that inhibition mitochondrial fission suppressed oxidative and alleviated dysfunction cardiac mice. However, no research has confirmed whether mitochondria accentuates hyperglycemia‐induced cardiomyoblast through regulating fatty acid oxidation (FAO). We used H9c2 cardiomyoblasts exposed to high glucose (HG) 33 mM simulate DCM vitro. Excessive fission, poor cell...
To study the expression of Rho kinase (Rho associated coil forming protein kinase-1, ROCK-1) and its substrate myosin phosphatase target subunit 1 (myosin subunit-1, MYPT-1), connexin 40 (Cx40) 43 (Cx43) in left atrial appendage patients with fibrillation, explore role ROCK signaling pathway fibrillation underlying mechanism. Methods: undergoing open heart surgery were divided into two groups; group (AF group) sinus rhythm (SR group). About 100 mg tissue was taken during quickly frozen...
This work organically integrates a systematic and individualized nursing plan with big data technology applies it to the care of patients chronic obstructive pulmonary disease (COPD) respiratory failure (RF) explores continuous model based on modern technologies improve COPD RF. It aims relieve symptoms RF, reduce number acute episodes RF hospitalizations, quality life patients. One hundred hospitalized in medicine department tertiary hospital were selected categorized into control...
ObjectiveTo study the neurobehavioral impairment caused by extremely low frequency electromagnetic field (ELF EMF) with high-intensity in population occupational exposure and provide evidence for prevention of disease health risk assessment. MethodsOccupational survey was conducted two thermal power plants, which intensity levels at 7 key working posts were detected examination, questionnaire interview test 88 workers 57 without exposure. ResultsThe average electric level 0.001–10.363 kV/m...