A5017220768- Mosquito-borne diseases and control
- Forensic Entomology and Diptera Studies
- Dengue and Mosquito Control Research
- Malaria Research and Control
- Insect and Pesticide Research
- Diptera species taxonomy and behavior
- Insect behavior and control techniques
- Insect Pest Control Strategies
- Insect symbiosis and bacterial influences
- Insect Resistance and Genetics
- Yersinia bacterium, plague, ectoparasites research
- Insects and Parasite Interactions
- Insect Utilization and Effects
- Forensic and Genetic Research
- Viral Infections and Vectors
- Insect and Arachnid Ecology and Behavior
- COVID-19 epidemiological studies
- Paleopathology and ancient diseases
- Blood Pressure and Hypertension Studies
- HIV Research and Treatment
- Essential Oils and Antimicrobial Activity
- Animal Ecology and Behavior Studies
- Medical Device Sterilization and Disinfection
- Vector-borne infectious diseases
- Mathematical and Theoretical Epidemiology and Ecology Models
Ministry of Health
2015-2025
Institute for Medical Research
2014-2025
University of Malaya
2011-2017
Dengue has enormous health impacts globally. A novel approach to decrease dengue incidence involves the introduction of Wolbachia endosymbionts that block virus transmission into populations primary vector mosquito, Aedes aegypti. The wMel strain previously been trialed in open releases Ae. aegypti; however, wAlbB shown maintain higher density than at high larval rearing temperatures. Releases aegypti mosquitoes carrying were carried out 6 diverse sites greater Kuala Lumpur, Malaysia, with...
Antimicrobial resistance is currently a major global issue. As the rate of emergence antimicrobial has superseded discovery and introduction new effective drugs, medical arsenal now experiencing shortage drugs to combat diseases, particularly against diseases caused by dreadful multidrug-resistant strains, such as methicillin-resistant Staphylococcus aureus (MRSA). The ability fly larvae thrive in septic habitats prompted us determine antibacterial activity minimum inhibitory concentrations...
Wolbachia are maternally inherited endosymbiotic bacteria found within many insect species. Aedes mosquitoes experimentally infected with being released into the field for Aedes-borne disease control. These infections induce cytoplasmic incompatibility which is used to suppress populations through incompatible matings or replace reproductive advantage provided by this mechanism. However, presence of naturally occurring in target could interfere both population replacement and suppression...
Aedes aegypti mosquitoes carrying the w AlbB Wolbachia strain show a reduced capacity to transmit dengue virus. has been introduced into wild Ae. populations in several field sites Kuala Lumpur, Malaysia, where it persisted at high frequency for more than 2 years and significantly incidence. Although these encouraging results indicate that releases can be an effective control strategy, long-term success depends on maintaining population frequencies virus transmission inhibition, both could...
The Sterile insect technique (SIT) has been successfully used in agricultural pest control, leading to interest its application for public health, particularly controlling Aedes mosquitoes the USA, Italy, Cuba, and Greece. Malaysia conducted a small-scale SIT pilot trial since 2019 dengue control. This study evaluates mosquito populations treated untreated sites through three objectives: (1) comparing mean larvae per trap (MLT) cases Ae. aegypti albopictus; (2) estimating survival rates wild...
Abstract The emergence of multidrug‐resistant bacterial strains has prompted the reintroduction maggot therapy in treatment chronic, infected wounds. Many previous studies have demonstrated potent antibacterial activity larval excretions/secretions blowfly Lucilia sericata ( M eigen) (Diptera:Calliphoridae) against bacteria. However, its sibling species, cuprina W iedemann) a wide range pathogenic bacteria never been determined. aim this study was to develop new procedure produce whole body...
The health-enhancing benefits of physical activity (PA) on hypertension and diabetes have been well documented for decades. This study aimed to determine the association PA with systolic diastolic blood pressure as glucose in Malaysian adult population. Data were extracted from 2011 National Health Morbidity Survey (NHMS), a nationally representative, cross-sectional study. A two-stage stratified sampling method was used select representative sample 18,231 adults aged 18 years above. levels...
Dengue is endemic in Malaysia, and vector control strategies are vital to reduce dengue transmission. The Wolbachia strain wAlbB carried by both sexes of Ae. aegypti was released Mentari Court, a high-rise residential site, October 2017 stopped after 20 weeks. frequencies still being monitored at multiple traps across this providing an opportunity examine the spatiotemporal distribution mosquito density with respect year, block, floor, using spatial interpolation ArcGIS, GLMs, contingency...
Wolbachia-based vector control strategies have been proposed as a mean to augment the existing measures for controlling dengue vector. Prior utilizing Wolbachia in novel strategies, it is crucial understand Wolbachia-mosquito interactions. Many studies only focused on prevalence of female Aedes albopictus with lack attention infection male Ae. which also affects effective expression induced- cytoplasmic incompatibility (CI). In this study, field surveys were conducted screen status and from...
Extensive usage and heavy reliance on insecticides have led to the development of insecticide resistance in German cockroach, Blattella germanica (L.). Six field-collected strains B. from Singapore were used investigate fipronil dieldrin. The three (Boat Quay, Cavenagh Road, Ghimmoh Road) with greatest subjected selection bait up F5 generation. Synergism assay molecular detection a target site mutation elucidate mechanism these strains. With exception Road strain, all parental susceptible...