- Traumatic Brain Injury Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Injury Epidemiology and Prevention
- Cardiac Arrest and Resuscitation
- Emergency and Acute Care Studies
- Suicide and Self-Harm Studies
- Kawasaki Disease and Coronary Complications
- Mechanical Circulatory Support Devices
- Spinal Fractures and Fixation Techniques
- Poisoning and overdose treatments
- Physical Education and Training Studies
- Trauma and Emergency Care Studies
- Coronary Artery Anomalies
- Meta-analysis and systematic reviews
- Child Abuse and Related Trauma
- Sports Performance and Training
- Cerebral Palsy and Movement Disorders
- Radiation Dose and Imaging
- Vestibular and auditory disorders
- Gun Ownership and Violence Research
- Nausea and vomiting management
- Delphi Technique in Research
- Adenosine and Purinergic Signaling
- Resilience and Mental Health
- Pediatric Pain Management Techniques
Children's Hospital of Philadelphia
2016-2025
University of Pennsylvania
2017-2025
The University of Texas Southwestern Medical Center
2024
Medical College of Wisconsin
2024
Boston Children's Hospital
2024
National Center for Injury Prevention and Control
2023
California University of Pennsylvania
2023
Pennsylvania Department of Health
2022
National Institute of Neurological Disorders and Stroke
2022
Pfeiffer University
2022
Up to one-third of children with concussion have persistent postconcussion symptoms lasting beyond 4 weeks. Females been shown prolonged recovery compared males. This study examined characteristics in pediatric athletes investigate the underlying factors that may contribute this difference and their relation trajectories females males.A retrospective cohort patients sports-related (SRC).A subspecialty program.One hundred ninety-two records were reviewed, 75 117 males, ages 7 18 years old.Sex...
ObjectiveTo describe the similarities and differences in evaluation treatment of multisystem inflammatory syndrome children (MIS-C) at hospitals US.Study designWe conducted a cross-sectional survey from June 16 to July 16, 2020, US children's regarding protocols for management patients with MIS-C. Elements included characteristics hospital, clinical definition MIS-C, evaluation, treatment, follow-up. We summarized key findings compared results centers which >5 had been treated vs those ≤5...
Fatal poisoning is a preventable cause of death among young children. Understanding factors surrounding these deaths will inform future prevention efforts. Our objective was to describe the characteristics fatal pediatric poisonings using child review data.We acquired data from 40 states participating in National Fatality Review-Case Reporting System on attributed children aged ≤5 years 2005 2018. We analyzed select demographic, supervisor, investigation, and substance-related variables...
Concussion is a common injury in the adolescent and young adult populations. While branched chain amino acid (BCAA) supplementation has shown improvements neurocognitive sleep function pre-clinical animal models of mild to moderate traumatic brain (TBI), date, no studies have been performed evaluating efficacy BCAAs concussed adolescents adults. The goal this pilot trial was determine efficacy, tolerability, safety varied doses oral group study conducted as pilot, double-blind, randomized...
ABSTRACT Purpose Evaluate the discriminatory ability of two clinical measures and one device-based measure gait balance for concussed youth. Methods We enrolled 81 cases 90 controls age 14–18 yr old from August 2017 to June 2018. Controls were recruited a suburban high school, concussion program an academic pediatric tertiary care center. Tests included measures: 1) complex tandem gait, scored as sway/errors walking forward backward eyes open closed; 2) Modified Balance Error Scoring System...
Objective: To characterize the relationship of sociodemographic factors to adherence provider recommendations for pediatric concussion. Setting: Primary care (PC) practices within Children's Hospital Philadelphia network. Participants: Patients aged 5 18 years old who presented any PC site concussion from September 26, 2019, December 31, 2019. Design: Retrospective medical record review. Main measures: The primary outcome was follow-up as defined by (1) continued until clearance return full...
Background: Pre-existing mental health diagnoses may contribute to greater emotional symptom burden and prolonged recovery after concussion. Hypothesis: Youth with pre-existing will have burden, risk for delayed return exercise, more from concussion than those without diagnoses. Study Design: Prospective cohort. Level of Evidence: 3. Methods: A prospective registry youth was examined differences in injury develop a predictive model recovery. The impact individual total number (0, 1, 2, 3+)...
The objective of this study was to measure the impact a structured intervention on pain management in pediatric emergency department (ED).Data were prospectively collected from children presenting an urban tertiary care ED before and after intervention. Data rate timeliness analgesic administration, assessment reassessment pain, periprocedural anesthesia, patient satisfaction. developed by multidisciplinary committee composed physicians, nurses, child life specialists focused correcting...
To determine the proportion of non-concussed, neurologically normal children with failures on a vestibular and oculomotor examination for concussion performed in an acute setting.
Background Three sources used for poisoning surveillance—child fatality reviews (CFRs), poison centre (PC) calls and death certificates—employ disparate data methodologies. Our study objectives were to (1) characterise the number of fatalities captured by CFRs PC compared with certificates age (2) compare demographic substance characteristics three sources. Methods We acquired CFR from National Fatality Review-Case Reporting System (NFR-CRS), Poison Data (NPDS) certificate Centers Disease...
ABSTRACT Aim The study aim was to develop an age‐appropriate definition of sport and exercise in children adolescents for use concussion research management. Methods A modified Delphi methodology, with three rounds consensus defined a priori as ≥ 80% agreement. Results Thirty‐one participants (13 male, 18 female) from 13 countries, including clinical psychologists, epidemiologists, implementation scientists, neurologists, neuropsychologists, neurosurgeons, paediatric emergency physicians,...
Introduction Concussion affects over 400 000 Canadians annually, with a range of causes and impacts on health-related quality life. Research to date has disproportionately focused athletes, military personnel level I trauma centre patients, may not be applicable the broader community. The TRANSCENDENT Program aims address patient- clinician-identified research priorities, through integration clinical data from patients all ages injury mechanisms, patient-reported outcomes objective...
The aim of the study was to compare presenting clinical and laboratory features among children meeting surveillance definition for multisystem inflammatory syndrome in (MIS-C) across a range illness severities.This is retrospective single-center patients younger than 21 years between March 1 May 15, 2020. Included met Centers Disease Control Prevention criteria MIS-C (inflammation, fever, involvement 2 organ systems, lack alternative diagnoses). We defined 3 subgroups by outcomes: (1)...
To evaluate the discriminatory ability of different repetition increments saccades and gaze stability testing for diagnosing concussion in adolescents.Cross-sectional.Suburban high school academic pediatric tertiary care center.Sixty-nine adolescent athletes within 28 days a sports- or recreation-related 69 without recent concussion.Symptom provocation with horizontal vertical performed up to 30 repetitions.Sensitivity specificity at 10-repetition (≤10, ≤20, ≤30) area under receiver...
To determine the relationship between patient characteristics and performance on visio-vestibular examination (VVE) in a cohort of healthy youth athletes explore potential association VVE other standardized concussion batteries.Cross-sectional.Suburban middle high school.One hundred ninety subjects age 11 to 18 enrolled before their respective scholastic sport season August 2017 March 2020.Patient age, sex, history, comorbidities, hours weekly exercise, Sport Concussion Assessment Tool, 5th...