About
Contact & Profiles
A5039991170
Research Areas
- Ubiquitin and proteasome pathways
- Endoplasmic Reticulum Stress and Disease
- Pancreatic function and diabetes
- Diabetes Management and Research
- Toxoplasma gondii Research Studies
- Diabetes and associated disorders
University of Florida
2020-2024
Abstract During type 1 diabetes (T1D) progression, beta cells become dysfunctional and exhibit reduced first-phase insulin release. While this period of cell dysfunction is well established, its cause underlying mechanism remain unknown. To address knowledge gap, live human pancreas tissue slices were prepared from autoantibody- negative organ donors without (ND), positive for one or more islet autoantibodies (AAb+), with T1D within 0-4 years diagnosis (T1D+). Dynamic imaging physiological...
10.1101/2024.12.29.630665
preprint
EN
cc-by-nc-nd
bioRxiv (Cold Spring Harbor Laboratory)
2024-12-29
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