- Respiratory Support and Mechanisms
- Sepsis Diagnosis and Treatment
- Neonatal Respiratory Health Research
- Wound Healing and Treatments
- Acute Kidney Injury Research
- Cardiac, Anesthesia and Surgical Outcomes
- Nosocomial Infections in ICU
- Inflammasome and immune disorders
- Infant Development and Preterm Care
- Burn Injury Management and Outcomes
- Kawasaki Disease and Coronary Complications
- Mechanical Circulatory Support Devices
- Respiratory viral infections research
- Cardiovascular Issues in Pregnancy
- Cardiac Arrest and Resuscitation
- Rabies epidemiology and control
- Hemodynamic Monitoring and Therapy
University of Cape Town
2023
Red Cross War Memorial Children's Hospital
2023
Chris Hani Baragwanath Hospital
2015-2020
University of the Witwatersrand
2019-2020
Limited data exist about the international burden of severe sepsis in critically ill children.To characterize global prevalence, therapies, and outcomes pediatric intensive care units to better inform interventional trials.A point prevalence study was conducted on 5 days throughout 2013-2014 at 128 sites 26 countries. Patients younger than 18 years age with as defined by consensus criteria were included. Outcomes therapies used, new or progressive multiorgan dysfunction, ventilator-...
High-flow humidified oxygen (HFHO) therapy has demonstrated benefit in infants with bronchiolitis.To investigate the efficacy of HFHO moderate to severe viral bronchiolitis, when used outside paediatric intensive care unit (PICU), a hospital limited PICU resources.A randomised controlled trial, which enrolled 28 between 1 month and 2 years age, clinical diagnosis acute bronchiolitis respiratory distress. Participants were receive 2L/kg/min or by nasal cannula/ face mask. Respiratory rate,...
To describe the prevalence of pediatric acute respiratory distress syndrome (pARDS) and characteristics children with pARDS in South African PICUs.Observational multicenter, cross-sectional point-prevalence study.Eight PICUs four provinces.All beyond neonatal period under 18 years age admitted to participating PICUs.None.Clinical demographic data were prospectively collected on a single day each month, from February July 2022, using centralized database. Cases or at risk identified 2015...
Multisystem inflammatory syndrome in children (MIS-C) is a relatively new clinical entity that has been described during the SARS-CoV-2 pandemic.[3][4] These studies were supported by later reports showed as number of COVID-19 infections declined, so did MIS-C cases. [5]The Western Cape, being initial epicentre within South Africa, had their first cases at beginning June 2020. [6]aediatric multisystem temporally associated with (PIMS-TS) and are synonymous names given to this syndrome....
Herpes simplex virus has been reported in the literature to commonly complicate burn wounds. However, there is paucity of such data South African setting.Eight paediatric burns patients with ages ranging between 10 months and 5 years presented a febrile maculopapular rash illness ward large tertiary hospital. The became vesicular three cases, involving limbs face. Varicella was suspected.Medical records suspected cases were reviewed. Blood, fluid scab samples collected. Electron microscopy...