A5087818957- Cancer Cells and Metastasis
- Neuroendocrine Tumor Research Advances
- Lung Cancer Research Studies
- Cancer Genomics and Diagnostics
- Virus-based gene therapy research
- Cell Image Analysis Techniques
- Pancreatic and Hepatic Oncology Research
- Quantum Dots Synthesis And Properties
- Advanced biosensing and bioanalysis techniques
- Advanced Nanomaterials in Catalysis
- Neuroblastoma Research and Treatments
- Viral gastroenteritis research and epidemiology
- Viral Infections and Outbreaks Research
- Glioma Diagnosis and Treatment
Luxembourg Institute of Health
2022
Institut Pasteur Korea
2018
An obstacle to effective uniform treatment of glioblastoma, especially at recurrence, is genetic and cellular intertumoral heterogeneity. Hence, personalized strategies are necessary, as means stratify potential targeted therapies in a clinically relevant timeframe. Functional profiling drug candidates against patient-derived glioblastoma organoids (PD-GBO) holds promise an empirical method preclinically discover potentially treatments individual tumors. Here, we describe our establishment...
Imaging of specific intracellular target proteins in living cells has been great challenge and importance for understanding events elucidating various biological phenomena. Highly photoluminescent water-soluble semiconductor nanocrystal quantum dots (QDs) have extensively applied to cellular imaging applications due the long-term photostability tunable narrow emission spectra with broad excitation. Despite success bioimaging diagnostic applications, visualization targets live still...
The massive epidemic of Ebola virus disease (EVD) in West Africa, followed recent months by two outbreaks the Democratic Republic Congo, underline importance this severe disease. Because (EBOV) must be manipulated under biosafety level 4 (BSL4) containment, discovery and development virus-specific therapies have been hampered. Recently, a transient transfection-based transcription- replication competent virus-like particle (trVLP) system was described, enabling modeling entire EBOV life...
Lung carcinoids are neuroendocrine tumors representing 1 to 2% of lung cancers. This study outlines the case a patient with metastatic atypical carcinoid who presented pleural effusion and progression liver metastases after developing resistance conventional treatments. Personalized functional profiling (PFP), i.e. drug screening, was performed in ex-vivo spheroids obtained from patient’s metastasis identify potential therapeutic options. The screening results revealed cediranib, an...