- Circular RNAs in diseases
- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- Enhanced Recovery After Surgery
- Ubiquitin and proteasome pathways
- RNA Research and Splicing
- Lung Cancer Diagnosis and Treatment
- Nausea and vomiting management
- Cancer, Hypoxia, and Metabolism
- Cholesterol and Lipid Metabolism
- Extracellular vesicles in disease
- Ferroptosis and cancer prognosis
- Inflammasome and immune disorders
- RNA modifications and cancer
- Histone Deacetylase Inhibitors Research
- Luminescence Properties of Advanced Materials
- Nanoplatforms for cancer theranostics
- Intraperitoneal and Appendiceal Malignancies
- Protein Degradation and Inhibitors
- Hippo pathway signaling and YAP/TAZ
- Sphingolipid Metabolism and Signaling
Sun Yat-sen University
2025
Xiangya Hospital Central South University
2019-2023
Central South University
2019-2023
National Clinical Research Center for Digestive Diseases
2023
West China Medical Center of Sichuan University
2020
Sichuan University
2018
MicroRNAs have been reported to play critical roles in the regulation of non-small-cell cancer (NSCLC) development, but role microRNA (miR)-331-3p NSCLC is still unclear. In this study, expression levels miR-331-3p tumor tissues and adjacent normal were examined by quantitative RT-PCR, relationship between patient clinicopathological characteristics was analyzed. The effects on epithelial-mesenchymal transition (EMT), migration, metastasis cells determined vitro vivo. Direct functional...
BACKGROUND:Colorectal cancer (CRC) is an extremely common gastrointestinal malignancy. MATERIAL AND METHODS:Three mRNA and 2 microRNA microarray datasets were downloaded from the Gene Expression Omnibus (GEO) database. Differentially expressed genes (DEGs) microRNAs (DEMs) obtained. The Database for Annotation, Visualization, Integrated Discovery (DAVID) program was utilized to perform gene ontology (GO) enrichment analysis Kyoto Encyclopedia of Genes Genomes (KEGG) pathway analysis....
Abstract CIB1 is a homolog of calmodulin that regulates cell adhesion, migration, and differentiation. It has been considered as an oncogene in many tumor cells; however, its role lung adenocarcinoma (LAC) not studied. In this study, the expression levels LAC tissues adjacent normal were examined by immunohistochemistry, relationship between patient clinicopathological characteristics was analyzed. The effects on epithelial–mesenchymal transition (EMT), metastasis cells determined vitro...
Colorectal cancer (CRC) is one of the most common malignancies worldwide. The aim present study was to investigate expression microRNA-144 (miR-144) and C-X-C motif chemokine ligand 11 (CXCL11) in CRC their association. Data from Gene Expression Omnibus (GEO) DataSets were analyzed obtain profile CXCL11 CRC. Subsequently, serum samples collected 65 subjects, including 39 patients with 26 controls; adjacent normal tissues all measured these specimens. After searching for potential regulator...
Accumulating evidence has demonstrated that long non‑coding RNAs (lncRNAs) are frequently overexpressed in colorectal cancer (CRC). However, few related lncRNA signatures have been established for predicting CRC metastasis. The purpose of the present study was to identify lncRNAs serve key roles metastasis human CRC, and their potential downstream targets. A total 31 biopsy samples were collected, expression intergenic non‑protein coding RNA‑467 (linc00467) its association with clinical...
Abstract Background: Day surgery has been widely carried out in medical developed countries such as Europe and the United States with high efficiency, safety economy. The development of thoracic day started late, currently only a few top three hospitals carry surgery. In recent years, continuous in-depth application concept accelerated rehabilitation (ERAS) field surgery, ERAS also entered clinical practice remarkable results. At present, is still its infancy, robot-assisted brought new...