Chunhui Li

ORCID: 0000-0003-2186-5137
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About
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Research Areas
  • Optical Coherence Tomography Applications
  • Photoacoustic and Ultrasonic Imaging
  • Ultrasound Imaging and Elastography
  • Coronary Interventions and Diagnostics
  • Ultrasound and Hyperthermia Applications
  • Corneal surgery and disorders
  • Ultrasonics and Acoustic Wave Propagation
  • Radiomics and Machine Learning in Medical Imaging
  • Nanoplatforms for cancer theranostics
  • Prostate Cancer Diagnosis and Treatment
  • Retinal Imaging and Analysis
  • Corneal Surgery and Treatments
  • Clostridium difficile and Clostridium perfringens research
  • Esophageal Cancer Research and Treatment
  • Blood Pressure and Hypertension Studies
  • Nanoparticle-Based Drug Delivery
  • Cardiovascular Health and Disease Prevention
  • Advanced Fluorescence Microscopy Techniques
  • Urinary and Genital Oncology Studies
  • Bladder and Urothelial Cancer Treatments
  • Ocular Surface and Contact Lens
  • Neural and Behavioral Psychology Studies
  • Prostate Cancer Treatment and Research
  • Liver Disease Diagnosis and Treatment
  • Advanced Nanomaterials in Catalysis

University of Dundee
2016-2025

Wuhan Institute of Technology
2025

South China University of Technology
2024-2025

Affiliated Hospital of Hebei University
2023-2025

Second Hospital of Hebei Medical University
2006-2024

First Hospital of Qinhuangdao
2024

Hebei Medical University
2006-2024

Dalian University
2021-2024

Zhujiang Hospital
2022-2024

Southern Medical University
2022-2024

The mechanical properties of skin are important tissue parameters that useful for understanding patho-physiology, which can aid disease diagnosis and treatment. This paper presents an innovative method employs phase-sensitive spectral-domain optical coherence tomography (PhS-OCT) to characterize the biomechanical by measuring surface waves induced short impulses from a home-made shaker. Experiments carried out on single double-layer agar–agar phantoms, different concentrations thickness, in...

10.1098/rsif.2011.0583 article EN Journal of The Royal Society Interface 2011-11-02

We report on a noninvasive and noncontact all-optical method to measure the elasticity of cornea. use pulsed laser excite surface acoustic waves (SAW) that propagate corneal surface, then phase-sensitive optical coherence tomography system remotely record SAWs from which is estimated. In addition, able provide real-time tomographic images cornea being examined, an important consideration for clinical studies. While precisely maintaining range intraocular pressures (IOP), series measurements...

10.1364/ol.37.001625 article EN Optics Letters 2012-05-07

We report on a quantitative elastography technique achieved by combining phase-sensitive optical coherence tomography (PhS-OCT) with the surface acoustic wave (SAW) method. Different from traditional elastography, is impulse-stimulated SAW, rather than shear waves. PhS-OCT serves not only as detector to measure SAW signals but also means provide cross-sectional image of sample. The experimental results indicate that combination feasible heterogeneous tissue samples.

10.1364/ol.37.000722 article EN Optics Letters 2012-02-15

Granular hydrogel matrices have shown significant advantages in mesenchymal stem cell (MSC) delivery and tissue ingrowth due to their minimally invasive injection capabilities porous structures. However, creating granular hydrogels that simultaneously mimic the nanofilamentous architecture of natural extracellular matrix (ECM) enhance retention vivo immunoregulation a diabetic microenvironment remains challenging. In this study, we present nanoengineered supramolecular with nanofibrillar...

10.1021/acsnano.4c11414 article EN ACS Nano 2025-02-11

We report on a noncontact photoacoustic imaging (PAI) technique in which low-coherence interferometer [(LCI), optical coherence tomography (OCT) hardware] is utilized as the acoustic detector. A synchronization approach used to lock LCI system at its highly sensitive region for detection. The experimentally verified by of scattering phantom embedded with hairs and blood vessels within mouse ear vitro. system's axial lateral resolutions are evaluated 60 30 μm, respectively. experimental...

10.1364/ol.36.003975 article EN Optics Letters 2011-10-05

Advances in the field of laser ultrasonics have opened up new possibilities medical applications. This paper evaluates this technique as a method that would allow for rapid characterization elastic properties soft biological tissue. In doing so, we propose novel approach utilizes low coherence interferometer to detect laser-induced surface acoustic waves (SAW) from tissue-mimicking phantoms. A Nd:YAG focused line-source is applied one- and two-layer agar-agar phantoms, generated SAW signals...

10.1364/oe.19.010153 article EN cc-by Optics Express 2011-05-09

Breast cancer is one of the rapidly increasing cancers among women and a significant cause cancer-related morbidity mortality worldwide. Therefore, current study was designed to examine compare trends breast incidence (BCI) during observed period (1990-2015) in specific age groups investigate age-specific, time period, birth cohort-related effects on BCI China, India, Pakistan, Thailand.Data related were retrieved from Institute for Health Metrics Evaluation. Age-period-cohort model joint...

10.2147/cmar.s208323 article EN cc-by-nc Cancer Management and Research 2019-09-01

Objectives: Upper tract urothelial carcinoma is a rare, aggressive lesion, with early detection key to its management. This study aimed utilise computed tomographic urogram data develop machine learning models for predicting tumour grading and staging in upper patients compare these predictions histopathological diagnosis used as reference standards. Methods: Protocol-based from 106 were obtained visualised 3D. Digital segmentation of the tumours was conducted by extracting textural...

10.1097/js9.0000000000001483 article EN cc-by-nc-nd International Journal of Surgery 2024-05-03

A series of ordered photoanodic architectures (including TiO2 nanotube arrays (TNT), ZnO nanorods, ZnO/TiO2 core/shell nanostructures) for CdS/CdSe sensitized solar cells (QDSCs), were fabricated directly on transparent conductive oxide glasses by a facile sol–gel assisted template process. The morphologies, optical and electrical properties TNTs co-sensitized have been demonstrated. effect CdSe deposition time the cell performance was clarified, growth mechanism quantum dots surface has...

10.1039/c2cp40568g article EN Physical Chemistry Chemical Physics 2012-01-01

Dynamic optical coherence elastography (OCE) tracks elastic wave propagation speed within tissue, enabling quantitative three-dimensional imaging of the modulus. We show that propagating mechanical waves are mode converted at interfaces, creating a finite region on order an acoustic wavelength where there is not simple one-to-one correspondence between and Depending details boundary’s geometry elasticity contrast, highly complex fields produced near boundary can substantially affect both...

10.1117/1.jbo.24.9.096006 article EN cc-by Journal of Biomedical Optics 2019-09-18

Metal-organic frameworks (MOFs) have been proven promising in addressing many critical issues related to gas separation and purification. However, it remains a great challenge optimize the pore environment of MOFs for purification specific mixtures. Herein, we report rational construction three isostructural microporous with 4,4',4"-tricarboxyltriphenylamine (H3TCA) ligand, unusual hexaprismane Ni6O6 cluster, functionalized pyrazine pillars [PYZ-x, x = -H (DZU-10), -NH2 (DZU-11), -OH...

10.1021/acsami.2c19779 article EN ACS Applied Materials & Interfaces 2023-01-10

Traditional high-quality OCTA images require multi-repeated scans (e.g., 4-8 repeats) in the same position, which may cause patient to be uncomfortable. We propose a deep-learning-based pipeline that can extract from only two-repeat OCT scans. The performance of proposed image reconstruction U-Net (IRU-Net) outperforms state-of-the-art UNet vision transformer and signal. results demonstrated mean peak-signal-to-noise ratio increased 15.7 24.2; structural similarity index measure improved...

10.1364/boe.486933 article EN cc-by Biomedical Optics Express 2023-04-21

Mechanical properties are important parameters that can be used to assess the physiologic conditions of biologic tissue. Measurements and mapping tissue mechanical aid in diagnosis, characterisation treatment diseases. As a non-invasive, non-destructive non-contact method, laser induced surface acoustic waves (SAWs) have potential accurately characterise elastic properties. However, challenge still exists when is directly applied because heat generation due energy deposition. This paper...

10.1364/boe.5.001403 article EN cc-by Biomedical Optics Express 2014-04-03

The maintenance of urinary bladder elasticity is essential to its functions, including the storage and voiding phases micturition cycle.The stiffness can be changed by various pathophysiological conditions.Quantitative measurement an step toward understanding disease processes improving patient care.As a nondestructive, noncontact method, laserinduced surface acoustic waves (SAWs) accurately characterize elastic properties different layers organs such as bladder.This initial investigation...

10.1364/boe.5.004313 article EN cc-by Biomedical Optics Express 2014-11-17

We tested the diagnostic accuracy of shear wave elastography to detect and phenotypically characterize prostate cancer compared with whole mount radical prostatectomy histopathology.In this prospective, protocol driven, study 212 consecutive men undergoing laparoscopic for clinically localized were recruited. Quantitative stiffness data on gland obtained in each patient using an endocavitary transrectal transducer before prostatectomy. Those a detailed histopathological examination specimen...

10.1016/j.juro.2018.03.116 article EN The Journal of Urology 2018-03-30
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