- Food Quality and Safety Studies
- Seaweed-derived Bioactive Compounds
- Microbial Metabolic Engineering and Bioproduction
- Algal biology and biofuel production
- Radiation Effects and Dosimetry
- biodegradable polymer synthesis and properties
- Enzyme Catalysis and Immobilization
- Biofuel production and bioconversion
- Photosynthetic Processes and Mechanisms
- Marine and coastal plant biology
- Protein Hydrolysis and Bioactive Peptides
- Phytochemicals and Antioxidant Activities
- Meat and Animal Product Quality
- Nutrition, Health and Food Behavior
- Agriculture, Soil, Plant Science
- Food Industry and Aquatic Biology
- Carbon dioxide utilization in catalysis
- Microbial Metabolites in Food Biotechnology
- Microbial Metabolism and Applications
- RNA and protein synthesis mechanisms
- GABA and Rice Research
- Viral Infectious Diseases and Gene Expression in Insects
- Redox biology and oxidative stress
- Enzyme Production and Characterization
- Polysaccharides and Plant Cell Walls
Chonnam National University
2016-2025
Chonnam National University Hospital
2015-2021
National Academy of Agricultural Science
2013
Korea Atomic Energy Research Institute
2008-2012
Korea Advanced Institute of Science and Technology
1992-2005
University of California, Berkeley
1983
University of California, San Diego
1983
Objectives We investigated whether systemic lupus erythematosus (SLE) patients could be distinguished based on the time of disease onset and, if so, groups differed in their clinical and laboratory features ethnically homogeneous Korean patients. Methods enrolled 201 SLE with available data at from cohort Chonnam National University Hospital. Sociodemographic, clinical, data, including autoantibodies, concomitant diseases were found diagnosis by reviewing patient charts. divided according to...
Sargassum fusiforme alginate (SF-Alg) possess many pharmacological activities, including hypoglycemic and hypolipidemic. However, the mechanisms of SF-Alg remain unclear due to its low bioavailability. In this study, we evaluated therapeutic effect on high-fat diet (HFD)/streptozotocin (STZ)-induced type 2 diabetes (T2D) mice. intervention was found significantly reduce fasting blood glucose (FBG), triglycerides (TG), total cholesterol (TC), while increasing high-density lipoprotein (HDL-c)...
Fermentation strategies for production of high concentrations poly(3-hydroxybutyrate-co-3-hydroxyvalerate) [P(3HB-co-3HV)] with different 3-hydroxyvalerate (3HV) fractions by recombinant Escherichia coli harboring the Alcaligenes latus polyhydroxyalkanoate biosynthesis genes were developed. Fed-batch cultures E. pH-stat feeding strategy facilitated and contents P(3HB-co-3HV) in a chemically defined medium. When solution was added order to increase glucose propionic acid 20 g/liter mM,...
ABSTRACT Poly(3-hydroxybutyrate) (PHB) was produced by cultivating several gram-negative bacteria, including Ralstonia eutropha , Alcaligenes latus and recombinant Escherichia coli . PHB recovered from these bacteria two different methods, the endotoxin levels were determined. When chloroform extraction method, level less than 10 units (EU) per g of irrespective bacterial strains employed content in cell. The NaOH digestion which particularly effective for recovery E. also examined removal....
Abstract BACKGROUND Pyropia yezoensis , rich in porphyran, is a medicine‐edible red alga. In the present study, physicochemical characteristics, conformational states and antitumor activities of novel porphyran extracted from high‐yield algal strain Chonsoo2 its two degraded derivatives by gamma irradiation were investigated. RESULTS water‐soluble, triple‐helical sulfated hetero‐galactopyranose, named PYP. PYP was at 20 kGy 50 kGy, giving low molecular weight comprising PYP‐20 PYP‐50,...
Lignocellulosic biomass has long been recognized as a potential sustainable source of sugars for biofuels. However, many physicochemical structural and compositional factors inhibit the enzymatic digestibility lignocellulosic biomass. In this study, efficient pretreatment method rice straw (RS) was developed RS hydrolysate applied in cultivation microalgae lipid production.Gamma ray irradiation (GRI) alkali solution were used pretreatment, saccharification carried out with lignocellulolytic...
Abstract The fermentative production of platform chemicals in biorefineries is a sustainable alternative to current petroleum‐refining processes. Industrial microorganisms, such as Escherichia coli , Saccharomyces cerevisiae and Corynebacterium glutamicum, have been engineered microbial cell factories that are able utilize biomass for the value‐added polymers. Compared E. S. C. glutamicum displays weak carbon catabolite repression can co‐utilize mixed sugars sources, without any significant...
Biocontainment systems have been developed to mitigate the concerns regarding biosafety and environmental risk because of possible escape genetically modified organisms into environment following large-scale outdoor cultivation. Here, we present a biocontainment system entailing Synechococcus elongatus PCC 7942, also engineered for α-farnesene production using de-evolutionary strategy. In this approach, gene cluster encoding β-carboxysome associated carbon concentrating mechanism (CCM) were...