A5058871007- Neuroscience and Neuropharmacology Research
- Parkinson's Disease Mechanisms and Treatments
- Neurological disorders and treatments
- Electrochemical Analysis and Applications
- Receptor Mechanisms and Signaling
- Ion Channels and Receptors
- Advanced biosensing and bioanalysis techniques
- Olfactory and Sensory Function Studies
- Nicotinic Acetylcholine Receptors Study
- Mitochondrial Function and Pathology
- Sleep and Wakefulness Research
- Nematode management and characterization studies
- Biochemical Analysis and Sensing Techniques
- Multicomponent Synthesis of Heterocycles
- Cannabis and Cannabinoid Research
- GABA and Rice Research
- Sirtuins and Resveratrol in Medicine
- RNA and protein synthesis mechanisms
- Mast cells and histamine
- Organoboron and organosilicon chemistry
- Phenothiazines and Benzothiazines Synthesis and Activities
- Psychedelics and Drug Studies
- Photoreceptor and optogenetics research
- Insect and Pesticide Research
- Medicinal Plants and Neuroprotection
Instituto Politécnico Nacional
2011-2024
Eli Lilly (United States)
2018
Some vegetable oils show beneficial effects in modulating neurodegeneration; this work, we evaluated the therapeutic potential of corn and olive against neurodegenerative processes using acute parkinsonism murine model induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) C57BL6 mice. The were quantified performance mice open field rotarod, grasp strength tests neuronal survival substantia nigra striatum determined immunohistochemistry. Extra-virgin oil decreased toxicity MPTP...
Flavonoids are natural substances obtained from plants. Most flavonoids cross the blood-brain barrier and exert a wide range of effects on central nervous system. These actions have been attributed to modulation GABA-A receptors. Although motor systems in system express high density receptors, physiological studies about nuclei scarce. Among basal ganglia, globus pallidus is potentially important for processing information related movement. The electrical activity neurons depends GABAergic...
The globus pallidus (GP) plays a key role in the overall basal ganglia (BG) activity. Despite evidence of cholinergic inputs to GP, their spiking activity GP neurons has not received attention. We examine effect local activation and blockade muscarinic receptors (MRs) spontaneous firing both normal ipsilateral striatum-lesioned rats. found that MRs produces heterogeneous responses rats: rats response evoked by depends on predrug rate; inhibition is higher than rats; number undergo lower Our...