A5085182312- Gestational Diabetes Research and Management
- Birth, Development, and Health
- Pregnancy and preeclampsia studies
- Epigenetics and DNA Methylation
- Neonatal Respiratory Health Research
- Biochemical Analysis and Sensing Techniques
- Eating Disorders and Behaviors
- Circadian rhythm and melatonin
- Infant Nutrition and Health
- Dietary Effects on Health
- Diet, Metabolism, and Disease
- Liver Disease Diagnosis and Treatment
- Fatty Acid Research and Health
- Iron Metabolism and Disorders
- Heart Rate Variability and Autonomic Control
- Sleep and Work-Related Fatigue
- Regulation of Appetite and Obesity
- Psychological and Temporal Perspectives Research
- Sleep and related disorders
- Advanced Chemical Sensor Technologies
- Ovarian function and disorders
- Diet and metabolism studies
- Maternal and fetal healthcare
- Olfactory and Sensory Function Studies
Kyoto Medical Center
2019-2025
Clinical Research Institute
2025
Kyoto Kacho University
2023-2025
Food & Nutrition
2025
University of Hyogo
2015-2020
Kyoto University
2020
Omega-3 polyunsaturated fatty acids (n-3 PUFAs) have unique properties that benefit female athletes. No study has examined the association between dietary inflammatory index (DII) and omega-3 index. Therefore, we investigated DII This cross-sectional included university athletes age- sex-matched controls. Data were collected from anthropometric assessments, a food frequency questionnaire (FFQ), blood tests for lipidomics. The energy-adjusted was calculated using FFQ. Seventy-four (mean...
Polycystic ovary syndrome (PCOS) is a common endocrine disorder among reproductive-aged women. While PCOS associated with an increased risk of obesity and insulin resistance, little known regarding the prevalence factors for nonalcoholic fatty liver disease (NAFLD) Japanese women PCOS. We estimated elevated enzymes, as index NAFLD, in PCOS.We retrospectively reviewed 102 who visited Department Gynecology, Kyoto Medical Center Japan from January 2000 to September 2016. Inclusion criterion was...
There is evidence to support that mastication may contribute the prevention of weight gain via reduction appetite sensations and subsequent energy intake. However, metabolic effect after consumption a daily meal, composed staple food (rice), soup, main side dishes, limited. Therefore, thorough on greater satiety thermic meal (TEM) was investigated in young women. In study 1, expenditure (EE) derived from masticatory muscle activity for 20 min measured while chewing hard, tasteless,...
Small-for-gestational-age (SGA) status has negative health consequences in neonates and later life. Low socioeconomic (SES) is a reported risk factor for adverse birth outcomes, such as SGA preterm (PTB). The present study investigated whether maternal SES associated with outcomes Japanese pregnant women.Retrospective data were collected 1970 women singleton pregnancies who delivered between January 2007 December 2011 at single center: low group (n = 197); controls 1773). was defined...
Abstract Objective Low birth weight (LBW) is a major public health issue as it increases the risk of noncommunicable diseases throughout life. However, genome-wide DNA methylation patterns full-term LBW infants (FT-LBWs) are still unclear. This exploratory study aimed to analyze differences in FT-LBWs compared with those normal (FT-NBWs) whose mothers were nonsmokers and had no complications. Initially, 702 Japanese women singleton pregnancies recruited. Of these, four five FT-NBWs selected...
生体リズム位相には個人差があり, 日中に活動しやすい朝型と夕方から夜間に活動しやすい夜型があることが知られている。そこで, "朝型と夜型では体内時計支配下にある自律神経活動や胃運動・食欲感覚の日中の変動が異なる"という仮説を立て, 実験による検証を行った。前夜22時より絶食した若年女性34名の胃電図, 心電図 (心臓自律神経活動) , 食欲感覚, 眠気, 深部体温 (耳内温) を8-20時まで1時間毎に測定した。食事と間食は定時に供した。全測定後に朝型-夜型を質問紙によりスコア化し, 中央値以上を朝型傾向群, 未満を夜型傾向群として結果を比較した。夜型傾向群は朝型傾向群と比べて, 終日, 交感神経活動優位の自律神経活動と高い心拍数, 眠気スコアが示された。また, 午前中の空腹感スコアが低く, 食後胃運動の周波数シフトに有意な上昇を認めなかった。本結果より, 午前中の食欲や活動が減弱しやすい夜型傾向群の特徴が示唆された。
Being born with large birthweight is considered as a risk of non-communicable diseases later in life. However, it not fully understood what kind maternal dietary intake during pregnancy affect birthweight. Therefore, we examined the association intakes and its changes large-for-gestational-age (LGA) births Japanese pregnant women. In prospective study, 245 women who visited Kyoto Medical Center were enrolled. Nutrition survey using brief-type self-administered diet history questionnaire...
【目的】我々は，夕方から夜にかけて活動しやすい夜型指向の女子大学生で，朝に低調な心臓自律神経活動を示すとともに，その胃の動きが食事時刻のばらつきに影響されることを報告している。そこで，同じ食事時刻で寮生活を送る女子高校生を対象に，朝型－夜型指向と朝の胃運動および体温，血圧，心拍数等のバイタル指標との関連を調べた。【方法】2014年5月にＡ高校寮内に設けた測定室で，女子生徒41名の血圧，耳内温，心電図，胃電図を朝食前の時間帯に10分間測定した。心電図から平均心拍数と心臓自律神経活動を求めた。胃運動，すなわち1分間に約3回生じる空腹期胃運動の評価のために，腹壁表面の電極から胃の活動電位を導出し，その胃電図波形をスペクトル解析する方法でパワー（強さ）とピーク周波数（出現頻度）を求めた。生活習慣と朝型－夜型指向は質問紙で調査し，10項目の質問への回答を1～5点で採点した合計点を朝型－夜型スコアとした。本研究では，平均点（28.5点）以上を朝型傾向群，未満を夜型傾向群として各項目を比較した。【結果】夜型傾向群は，朝型傾向群と比べて1）平日と休日の起床時刻が有意に遅く，2）心拍数が有意に高く...
Purpose of Investigation: The purpose is to identify factors related postpartum hemorrhage (PPH) that are evaluated during regular prenatal check-ups. Materials and Methods: Obstetric neonatal data were collected retrospectively for 1,922 women with singleton pregnancies who delivered vaginally. Results: Overweight exhibited more severe PPH cases compared normal (p = 0.04). Of pre-pregnancy body mass index (BMI), gestational weight gain (GWG), week delivery, weight, showed a significantly...
【目的】特別な支援が必要な児童生徒への食育では，学習者の保有する感覚を活用した教具の選択が重要とされるが，その有効性を検証した研究は少ない。我々は特別支援教育において立体識別感覚を重視した教具が広く活用されている現状に着目し，「障害の種類や程度が様々で特別な支援を必要とする児童生徒への食育において，立体教具は平面教具と比べて児童生徒のより高い関心と反応を引き出す」との仮説を立てた。この仮説の検証を目的として以下の研究を行った。【方法】学習者は肢体不自由を主とした障害を有するＳ養護学校小学～高等部の45名（参加率54.2％）であり，2013年9月に疑似収穫体験を主活動とする食育を行った。教具は，給食や栽培体験でなじみがある野菜8種類とした。B1...
エネルギーを有さない人工甘味料のスクラロースが食欲感覚や胃運動に及ぼす影響を, スクロースとの比較により明らかにすることを目的とした。15℃で150 mLのスクラロース溶液 (SR) , 等温・等量・同程度の甘さのスクロース溶液 (S) コントロール (軟水, W) を, 異なる日の朝9時に前夜22時より絶食した若年女性に負荷した。30 mLずつ分注したサンプルを口に含み口腔内に十分に行き渡らせてから飲み込む方法で甘味刺激を5回繰り返し, 0・1・5杯目の甘味の感じ方を調べた。胃電図, 心電図 (心拍数) 体温は, サンプル摂取20分前から摂取65分後まで測定し食欲感覚は15分毎に評価した。SとSRともに摂取直後の食欲を一過性に抑制しSRで低下が顕著だった。その後の食欲は溶液の甘味を強く感じるほど高まった。胃電図の応答はSとSRで異なり, 心拍数増加はSでのみ認められた。本結果よりSRは心拍数や体温は上昇させないが, 一過性に食欲を抑制し異なる胃運動を示すことがSとの比較において示唆された。
Abstract Objective: Low birth weight (LBW) is a major public health issue as it results in higher risk of non-communicable diseases throughout life. However, the genome-wide DNA methylation patterns LBW full-term infants (FT-LBWs) are still unclear. The aim this exploratory study was to compare differences between FT-LBWs and normal (FT-NBWs) whose mothers were non-smokers non-complication. Results: A total 702 Japanese singleton pregnancies recruited. prevalence preterm FT-LBW 3.4% 6.1%,...
Abstract Objective: Low birth weight (LBW) is a major public health issue as it increases the risk of noncommunicable diseases throughout life. However, genome-wide DNA methylation patterns full-term LBW infants (FT-LBWs) are still unclear. This exploratory study aimed to analyze differences in FT-LBWs compared with those normal (FT-NBWs) whose mothers were nonsmokers and had no complications. Initially, 702 Japanese women singleton pregnancies recruited. Of these, four five FT-NBWs selected...