A5074159008- Power Systems Fault Detection
- HVDC Systems and Fault Protection
- High-Voltage Power Transmission Systems
- Islanding Detection in Power Systems
- Energy, Environment, and Transportation Policies
- Electric Vehicles and Infrastructure
- Magnetic Properties and Applications
- Cancer Treatment and Pharmacology
- Cancer Immunotherapy and Biomarkers
- HER2/EGFR in Cancer Research
- Immunotherapy and Immune Responses
- Carbohydrate Chemistry and Synthesis
- Shape Memory Alloy Transformations
- Fluorine in Organic Chemistry
- Cancer, Hypoxia, and Metabolism
- Synthetic Organic Chemistry Methods
- RNA modifications and cancer
- Magnetic Properties of Alloys
- Colorectal Cancer Treatments and Studies
- Laser-Plasma Interactions and Diagnostics
- Gamma-ray bursts and supernovae
- Biochemical and Molecular Research
- Full-Duplex Wireless Communications
- Nuclear physics research studies
- Magnetic properties of thin films
National University of Defense Technology
2022-2024
Cornell University
2021-2024
China Southern Power Grid (China)
2023-2024
SC Johnson (United States)
2024
Xuzhou University of Technology
2023-2024
ShanghaiTech University
2019-2023
University of Chinese Academy of Sciences
2020-2023
Chinese Academy of Sciences
2007-2023
Shanghai Advanced Research Institute
2012-2023
Sichuan University
2012-2023
Background Increasing infiltration of CD8 + T cells within tumor tissue predicts a better prognosis and is essential for response to checkpoint blocking therapy. Furthermore, current clinical protocols use unfractioned cell populations as the starting point transduction chimeric antigen receptors (CARs)-modified cells, but optimal subtype CAR-modified remains unclear. Thus, accurately identifying group cytotoxic lymphocytes with high antitumor efficacy imperative. Inspired by theory yin...
Background The loss of tumor antigens and depletion CD8 T cells caused by the PD-1/PD-L1 pathway are important factors for immune escape. In recent years, there has been increasing research on traditional Chinese medicine in treatment. Cycloastragenol (CAG), an effective active molecule Astragalus membranaceus , found to have antiviral, anti-aging, anti-inflammatory, other functions. However, its antitumor effect mechanism not clear. Methods CAG was investigated MC38 CT26 mouse transplanted...
This article presents a novel phasor domain approach to determine the location of faults in non-homogeneous transmission lines. Best implementation requires synchronized voltage and current measurements at all terminals line. The overall line model with fault is established by systematically combining generalized compact models homogeneous sections. introduced as an additional state model. derivation procedure without further assumptions, resulting full consideration three phase asymmetry...
Identification of effective therapies for colorectal cancer (CRC) remains an urgent medical need, especially the microsatellite-stable (MSS) phenotype. In current study, a combination fruquintinib plus anti-PD-1 MSS CRC therapy was investigated. First, case advanced reported. After failure multiline therapy, patient finally achieved rapid response after receiving treatment. Then effect verified using murine syngeneic model CT26 cells (MSS). The results showed that cotreatment significantly...
This paper proposes a new fault location method for transmission lines in MMC-HVDC grids based on dynamic state estimation (DSE) and gradient descent. The only requires short data window of 5 ms after the occurrence therefore is applicable with high-speed tripping techniques. first builds high-fidelity linear model DC line, which accurately describes physical laws line during fault. Afterwards, consistency between measurements evaluated through DSE algorithm. Finally, actual corresponds to...
Hydroenergy is developed due to its low-cost and near-zero pollution emission properties; therefore, the efficient management of hydroenergy an important goal sustainable development for any nation, especially China, since it owns most abundant water resources around world. Developing not only effective response energy crisis but also a positive way cope with climate change in China. Nevertheless, research on China still comprehensive. This study reviews by combining geographical...
Accurate fault location reduces operating cost and outage time. This paper proposes a time-domain method to accurately locate faults in transmission lines, which only requires very short data window (several milli-seconds) during faults. First, the voltage distribution through line is obtained by solving matrix form partial differential equations using proposed numerical scheme. The scheme mathematically validated for problem, with optimal selection of time distance intervals ensure...
We investigate the pass-through of electric vehicle (EV) subsidies in 13 countries that account for 95 percent global EV sales from 2013 to 2020. Our results indicate high rates 70-80 on average. Pass-through is highest firms sell same models across multiple countries, consistent with uniform pricing by these firms, as well avoidance third-party arbitrage. find suggestive evidence higher tax incentives than direct consumer subsidies.
This paper proposes an improved noniterative fault location method on untransposed transmission lines without utilizing line parameters. Two-end three phase voltage and current phasor measurements before during the are typically required. First, parameter-free problem is formulated through multi-section models, necessary condition of solutions carefully investigated to determine maximum possible section number model. Afterwards, with determined number, analytical solution derived full...
Accurate fault location for underground cables in MMC-HVDC grids reduces the time finding faults as well system operational costs. For grids, data window during is usually short. During such severe transients, frequency dependent line parameters of have strong influence on accuracy. In this paper, a novel algorithm proposed. First, multi-layer model cable using partial differential equations proposed, which considers distributed and domain. Afterwards, numerical finite difference solution...
This paper proposes a novel phasor domain fault location method for two or three terminal double-circuit transmission lines sharing the same tower without requiring line parameters. First, models of and with faults are derived. The fully consider mutual coupling between circuits, distributed parameters, asymmetry structures, extensive types. Through modeling procedure, location, unsynchronized phase angle, resistance other internal states introduced as unknown variables, resulting in highly...
Immunotherapy emerges as an effective avenue for tumor elimination and has many advantages compared with traditional surgery, radiotherapy, chemotherapy. Tumor vaccines play important role in cancer immunotherapy, while the application of clinical usage is limited because only response can be induced by primary antigens. Accordingly, it a key point to activate T-cell some novel vaccines. Here, we applied phage display biopanning screened peptide (TY) that could combine...
In this paper, an improved dynamic state estimation (DSE) based protection (DSEBP) scheme is proposed for transmission lines in MMC-HVDC grids. Firstly, a model of the zone (DC line interest) constructed using differential and algebraic equations. The impact frequency dependent parameters mitigated through utilization "line mode" model. Then, novel Runge-Kutta (RK) discretization to consider dynamics control variables during electromagnetic transients, yielding reduced error as compared...
An efficient and general strategy to gem-difluoromethylenated α,β-unsaturated δ-lactones in high yields from various aldehydes (including aliphatic, aromatic, α,β-unsaturated, sterically hindered aldehydes) has been developed. This methodology was successfully applied for the preparation of two enantiomers goniothalamins (S)-1 (R)-1. gem-Difluoropropargylation cinnamaldehyde followed by resolution resulting homopropargylic alcohols mediated lipase Pseudomonas (AK) gave (R)-6 (S)-6. Selective...
Anti-epidermal growth factor receptor (EGFR) treatment has been successfully applied in clinical cancer therapy. However, the efficacy of first-generation reversible EGFR inhibitors, such as gefitinib and erlotinib, is limited by development drug-resistant mutations, including gatekeeper T790M mutation upregulation alternative signaling pathways. Second-generation irreversible inhibitors that were designed to overcome drug resistance due have thus far had success. Here, we report a novel...
Abstract An improved natural frequency based method is proposed to accurately locate faults in transmission lines. The only requires three phase instantaneous current measurements at the local terminal of line and compatible with protective relays using high‐speed tripping techniques. First, theoretical peak frequencies along entire spectrum measured currents are derived, for different fault types, locations resistances. Next, location determined by finding minimum average distance between...
Line parameters of underground cables (UGCs) in MMC-HVDC grids experience severe frequency dependent characteristics. For fault location UGCs grids, existing methods usually neglect the line parameters, which limits accuracy. To overcome this issue, a dynamic state estimation based (DSEFL) method for grid is proposed paper. Firstly, model UGC on multi-section multi-layer formulated to consider both and distributed characteristics parameters. Next, DSE algorithm used solve consistency...