A5001323567- Surface Treatment and Residual Stress
- RNA and protein synthesis mechanisms
- Metal Alloys Wear and Properties
- X-ray Diffraction in Crystallography
- Advanced Optical Imaging Technologies
- Protein Structure and Dynamics
- Gallbladder and Bile Duct Disorders
- semigroups and automata theory
- Chemical Synthesis and Analysis
- Crystallization and Solubility Studies
- Enzyme Structure and Function
- Collagen: Extraction and Characterization
- DNA and Nucleic Acid Chemistry
- Pediatric Hepatobiliary Diseases and Treatments
- Photosynthetic Processes and Mechanisms
- RNA modifications and cancer
- Urban and spatial planning
- Bacterial Genetics and Biotechnology
- Photorefractive and Nonlinear Optics
- Receptor Mechanisms and Signaling
- Optical Polarization and Ellipsometry
- Sports Performance and Training
- Semiconductor Lasers and Optical Devices
- Protein Hydrolysis and Bioactive Peptides
- Liquid Crystal Research Advancements
Tokyo University of Agriculture and Technology
2025
Osaka University
2012-2024
Sinto (Japan)
2012-2024
Aichi Medical University
2012-2023
Saiseikai Niigata Daini Hospital
2023
National Center for Global Health and Medicine
2023
Okayama University
2017-2022
SMC Corporation (Japan)
2020-2021
The University of Tokyo
1998-2020
Zen-Noh (Japan)
2020
An optically addressed parallel-aligned nematic-liquid-crystal spatial light modulator is developed for applications in optical information processing and interferometry. Its performance, including diffraction efficiency, measured, a theoretical analysis of efficiency performed. A comparison between the experimental results shows good agreement. The near-sinusoidal gratings written on device order 30%, which close to maximum.
Aim Several studies on the efficacy of ezetimibe, a potent inhibitor cholesterol absorption, in treating non‐alcoholic fatty liver disease (NAFLD) and steatohepatitis (NASH) have been published; however, results are inconsistent. We undertook meta‐analysis to evaluate ezetimibe NAFLD NASH. Methods PubMed, Medline, Cochrane Library Full Text Database were searched until June 2016. The main inclusion criteria included original investigating use for treatment Identification published work data...
The isolation of minor isomers [84]fullerene (C84), five in total, and their characterization by 13C NMR spectroscopy, have been reported for the first time. vis−near-infrared absorption spectra these are also reported. results indicate that isolated C84 have, order decreasing abundance, C2, Cs(a), Cs(b), D2d(I), D2(II) molecular point group symmetry. In addition, we found another isomer adjacent to Cs(b)-C84 HPLC chromatogram.
Abstract Neurotoxic peptides from venoms of scorpions and honey bees exhibit a consensus pattern in the two disulfide bridgings related to sequence portions Cys‐X‐Cys Cys‐X‐X‐X‐Cys. A revised three‐dimensional structure charybdotoxin, as determined by two‐dimensional nmr spectroscopy, confirms that cystine dislocation generates all these toxins common structural element, i.e., cystine‐stabilized α‐helical (CSH) motif, which may be correlated with their ion channel blocking activity.
To understand the DNA recognition mechanism of zinc finger motifs transcription factor Sp1, we have determined solution structure DNA-binding domain Sp1 by NMR techniques. The consists three Cys2His2-type motifs. They typical ββα folds and relatively random orientations. From analysis performed comparison between structures here previously reported other fingers, it was assumed that modes fingers 2 3 would be similar to those Zif268, in which each recognizes four base pairs strictly using...
The imidazole (15)N signals of histidine 64 (His(64)), involved in the catalytic function human carbonic anhydrase II (hCAII), were assigned unambiguously. This was accomplished by incorporating labeled as probes for solution NMR analysis, with at ring-N(delta1) and N(epsilon2), (13)Cat ring-Cepsilon1, (13)C all carbon nitrogen, or amide nitrogen glycine carbonyl carbon. Using pH dependence ring-(15)N a comparison between experimental simulated curves, we determined that tautomeric...
We developed a liquid-crystal-on-silicon (LCOS) spatial light modulator (SLM) for phase-only modulation. The SLM was designed mainly wavefront control in adaptive optics, optical manipulation, laser processing, etc. A dielectric multilayer mirror incorporated into the device to enhance reflectivity. number of pixels 792 x 612 and their size 20 microns square. range phase modulation exceeded one wavelength, light-utilization efficiency monochromatic approximately 90%. silicon backplane...
The aims of the study were to investigate differences in kinematics and kinetics between dominant nondominant leg during single-leg jumps without arm swing, determine relationship bilateral asymmetry isokinetic knee strength jump. Isokinetic jump measured 11 male participants. index was calculated for each parameter. For strength, there no significant legs. Significant correlations observed at 180 degrees per second indexes maximum flexion angle mean joint torque jumps. In conclusion,...
A heterologous overexpression system for mesophilic Pseudomonas aeruginosa holocytochrome c(551) (PA c(551)) was established using Escherichia coli as a host organism. Amino acid residues were systematically substituted in three regions of PA with the corresponding from thermophilic Hydrogenobacter thermophilus cytochrome c(552) (HT c(552)), which has similar main chain folding to c(551), but is more stable heat. Thermodynamic properties one single mutations (Phe-7 Ala, Phe-34 Tyr, or Val-78...
Differential scanning calorimetry (DSC) analyses of a series collagen model peptides suggest that 4-hydroxyproline (Hyp) and 4-fluoroproline (fPro) have different effects on the stability triple helices according to sequence amino acids stereochemistry at 4 positions these imino acids. The thermodynamic parameters indicate enhanced stabilities are classified into two types: enthalpy term is primarily responsible for helix (Pro-HypR-Gly)10, whereas entropy dominates (Pro-fProR-Gly)10....
Background and Aim Immunohistological evaluations are essential for diagnosing subepithelial tumors ( SET ). However, endoscopic ultrasound‐guided sampling using fine‐needle aspiration FNA ) needles is limited in its ability to procure core tissue immunostaining. Fine‐needle biopsy FNB may mitigate this limitation. The present study aimed examine the efficacy of procuring samples that enable diagnosis . Methods One hundred sixty patients were included separated into those whose obtained...
ABSTRACT Splice variants of certain genes impact on genetic biodiversity in mammals. The tumor suppressor TP53 gene (encoding p53) plays an important role the regulation tumorigenesis hepatocellular carcinoma (HCC). Δ40p53α is a naturally occurring p53 isoform that lacks N-terminal transactivation domain, yet little known about development HCC. Here, we first report HCC cell lines. In TP53+/Δ40 clones, clonogenic activity and survival dramatically decreased, whereas percentage...
Collagen model peptide (Pro-Pro-Gly)10 has a triple helical structure and undergoes thermal transition to single random coil structure. The temperature of the analogous peptides depends largely on amino acid substitution. Substitution Pro by 4-hydroxyproline (Hyp) or 4-fluoroproline (fPro) especially attracted attention because position substitution chirality hydroxyl group fluorine atom affect temperatures. Here, we demonstrated that (4(S)-fPro-Pro-Gly)10 takes structure, but...