J.-X. Gu

ORCID: 0000-0003-2251-7062
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About
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Research Areas
  • Liver Disease Diagnosis and Treatment
  • Liver physiology and pathology
  • Liver Disease and Transplantation
  • RNA modifications and cancer
  • Organ Transplantation Techniques and Outcomes
  • Natural Compounds in Disease Treatment
  • Pancreatic and Hepatic Oncology Research
  • MicroRNA in disease regulation
  • Autophagy in Disease and Therapy
  • Abdominal Surgery and Complications
  • RNA Research and Splicing
  • Pancreatitis Pathology and Treatment
  • COVID-19 Clinical Research Studies
  • Folate and B Vitamins Research

Second People’s Hospital of Huai’an
2016-2024

Xuzhou Medical College
2016-2024

Nanjing University of Chinese Medicine
2024

Nanjing Drum Tower Hospital
2014-2024

The purpose of this study was to further clarify the role and underlying mechanism miR-324-5p in gastric cancer.The expressions TSPAN8 as determined by qRT-PCR or Western blot were compared between cancer tissues normal tissues. Human cell line SGC-7901 cultured transfected with mimic/inhibitor pcDNA-TSPAN8. survival assessed viability apoptosis. Luciferase reporter gene assays performed explore interaction cells.MiR-324-5p decreased human carcinoma (n = 33), but protein expression increased...

10.1111/jphp.12995 article EN Journal of Pharmacy and Pharmacology 2018-08-29

The objective of this study was to compare effects octreotide and continuous hemofiltration versus alone in the treatment severe acute pancreatitis (SAP) complicated with respiratory distress syndrome (ARDS). It an experimental carried out from April 2016 2018. A total 86 cases SAP ARDS were randomly divided into group B, 43 each group. Group given alone, B combined octreotide. research findings showed that serum tumor necrosis factor (TNF-α), interleukin-1 (IL-1), IL-6, IL-8, diamine...

10.29271/jcpsp.2019.08.785 article EN Journal of College of Physicians And Surgeons Pakistan 2019-07-30

In this study the effects of S-adenosylmethionine (SAM) on experimental hepatic fibrotic rats induced by carbon tetrachloride (CCl(4)) and ethanol relevant potential mechanisms were explored. Hepatic rat models established with CCl(4) diluted in olive oil being drunk 10% water. SAM was used both for prevention treatment. Histological evaluation carried out hematoxylin-eosin (HE) Masson staining samples. Serum biochemical assays showed that alanine aminotransferase (ALT) increased albumin...

10.7868/s0026898416020270 article EN Молекулярная биология 2016-01-01
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