A5047223822- Genetic Mapping and Diversity in Plants and Animals
- Genetic Associations and Epidemiology
- Forensic and Genetic Research
- Genetic diversity and population structure
- Genetic and phenotypic traits in livestock
- Pleistocene-Era Hominins and Archaeology
- Race, Genetics, and Society
- Climate change impacts on agriculture
- Chemical Synthesis and Analysis
- Archaeology and ancient environmental studies
- Paleontology and Stratigraphy of Fossils
- Maritime and Coastal Archaeology
- Click Chemistry and Applications
- Synthetic Organic Chemistry Methods
- Forensic Anthropology and Bioarchaeology Studies
- Geomagnetism and Paleomagnetism Studies
- Morphological variations and asymmetry
- Calcium Carbonate Crystallization and Inhibition
- Cancer-related molecular mechanisms research
- Geological Formations and Processes Exploration
- Aeolian processes and effects
- Species Distribution and Climate Change
- Evolution and Paleontology Studies
- Bone and Dental Protein Studies
- Remote Sensing in Agriculture
University of Toronto
2017-2025
Canada Research Chairs
2017
University of Copenhagen
2017
University of Pittsburgh
2005
University of South Carolina
1994
Founder effects in modern populations The genomes of ancient humans can reveal patterns early human migration (see the Perspective by Achilli et al. ). Iceland has a genetically distinct population, despite relatively recent settlement (∼1100 years ago). Ebenesersdóttir examined Icelandic people, dating to near colonization Iceland, and compared them with modernday populations. DNA revealed that founders had Gaelic Norse origins. Genetic drift since initial left Icelanders allele frequencies...
<title>Abstract</title> Modern humans and archaic hominins, namely Denisovans Neanderthals, have been demonstrated to a long history of admixture. Specifically, some these admixture events adaptive allowed modern adapt their new environments outside Africa. Little research has done on the impact introgression genes associated with reproduction. In this study we report evidence putative 118 within that previously reproduction in mice or humans. From identified 11 core haplotypes, three...
Cascade reactions of internal and terminal alkynes, zirconocene hydrochloride, dimethylzinc, phosphinoyl imines (prepared in one step from aldehydes diphenylphosphinoyl amide) lead to allylic amides after aqueous workup. Microwave acceleration allows the completion this one-pot reaction sequence 10 min. These can be converted into a variety derivatives, including carbamates sulfonamides, or reacted prior workup with diiodomethane give novel C-cyclopropylalkylamides. A solution-phase...
The increasing awareness that hybridization, and resultant gene flow, plays a major role in animal diversification has led to growing number of studies have focused on assessing the morphological consequences this process. Analyses mammalian hybrids identified skeletal effects including suite anomalous dental sutural traits skull are present at high frequencies hybrid populations. These also detected consistent patterns shape size differences between parental taxa across wide variety...
Abstract Interbreeding between modern humans and archaic hominins, including Neanderthals Denisovans, occurred as migrated outside of Africa. Here, we report on evidence introgression from hominins within genomic regions associated with circadian rhythm chronotype using 76 worldwide human populations the Human Genome Diversity Project 1000 Genomes Project. We calculated extent indicative adaptive across autosomes identified that are suggested to be under positive selection. tested for a...
Abstract Modern humans and archaic hominins, namely Denisovans Neanderthals, have been demonstrated to a long history of admixture. Specifically, some these admixture events adaptive allowed modern adapt their new environments outside Africa. Little research has done on the impact introgression genes associated with reproduction. In this study we report evidence putative 118 within that previously reproduction in mice or humans. From identified 11 core haplotypes, three positively selected....
The last couple of decades have highlighted the importance studying hybridization, particularly among primate species, as it allows us to better understand our own evolutionary trajectory. Here, we report on genetic ancestry estimates using dense, full genome data from 881 olive ( Papio anubus ), yellow cynocephalus or olive-yellow crossed captive baboons Southwest National Primate Research Center. We calculated global and local information, imputed low coverage genomes (n = 830) improve...
In this study, we present the results of a genome-wide scan for signatures positive selection using data from four tribal groups (Kokana, Warli, Bhil, and Pawara) two caste (Deshastha Brahmin Kunbi Maratha) West Maharashtra State India, as well samples South Asian ancestry 1KG project (Gujarati Indian Houston, Texas Telugu UK). We used an outlier approach based on different statistics, including PBS, xpEHH, iHS, CLR, Tajima's D, recently developed methods: Graph-aware Retrieval Selective...