A5101842525- Neuroinflammation and Neurodegeneration Mechanisms
- Gut microbiota and health
- Neurological Disease Mechanisms and Treatments
- Anesthesia and Pain Management
- Spine and Intervertebral Disc Pathology
- Spinal Fractures and Fixation Techniques
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Protist diversity and phylogeny
- Vascular Malformations and Hemangiomas
- Lymphatic Disorders and Treatments
- Genetic and Kidney Cyst Diseases
- Bacteriophages and microbial interactions
- Cancer, Hypoxia, and Metabolism
- Clostridium difficile and Clostridium perfringens research
- Thyroid Cancer Diagnosis and Treatment
- Pancreatitis Pathology and Treatment
- Hepatitis B Virus Studies
- Glycosylation and Glycoproteins Research
- High Altitude and Hypoxia
- Probiotics and Fermented Foods
- Infectious Diseases and Tuberculosis
- Intracerebral and Subarachnoid Hemorrhage Research
- Flavonoids in Medical Research
- Insect symbiosis and bacterial influences
- Medicinal Plants and Bioactive Compounds
Northwest A&F University
2025
Northwest Normal University
2025
Soochow University
2025
First Affiliated Hospital of Soochow University
2025
Chongqing Medical University
2024
Children's Hospital of Chongqing Medical University
2024
Ningxia Medical University General Hospital
2024
Ningxia Medical University
2018-2024
Quzhou City People's Hospital
2023
Second Affiliated Hospital of Zhejiang University
2006-2022
Bilophila wadsworthia is a major member of sulfidogenic bacteria in human gut, it was originally recovered from different clinical specimens intra-abdominal infections and recently reported potentially linked to chronic metabolic disorders. However, there still insufficient understanding on its detailed function mechanism date.A B. strain isolated fresh feces latent autoimmune diabetes adults patient we investigated pathogenicity by oral administration specific-pathogen-free mice. Tissue...
Over the past ten years, more papillary thyroid microcarcinoma (PTMC) has been diagnosed frequently due to development of imaging technology, and incidence PTMC increased significantly. Ultrasound-guided percutaneous laser ablation (PLA) is mainly used for benign nodules, few studies have published on use PLA PTMC. In present study, a retrospective analysis was performed explore efficacy PTMC.A total 37 patients with who underwent were included in this study. Measurement lesion volume serum...
Abstract Di‐(2‐ethylhexyl) phthalate (DEHP) is one of the most commonly used plasticizers, and it widely applied in various plastic products. DEHP an endocrine‐disrupting chemical (EDC) that has been shown to disrupt function reproductive system females. Although many studies have potentially causes female toxicity, including depletion primordial follicle decreased sex hormone production, specific mechanisms by which affects reproduction remain unknown. In recent years, research focused on...
Astrocytes are proving to be critical for the development of cognitive functions. In addition, astrocytic activation contributes impairment induced by chronic cerebral hypoperfusion. Minocycline has been shown exhibit long-term neuroprotective effects in vascular rat models through inhibition astrogliosis, and demonstrated potential prevention treatment postoperative decline elderly patients. This study aimed examine effect minocycline on hippocampal astrocytes dysfunction aged mice. Mice...
Abstract The same prebiotics have produced inconsistent effects on microbiota when evaluated in different batch fermentation studies. To understand the reasons behind these discrepancies, we compared impact of one prebiotic formula inoculated fecal two frequently used systems: phosphate-buffered saline (PBS, oligotrophic) and basal culture medium (BCM, eutrophic). was monitored using 454 pyrosequencing. Negative controls (no prebiotic) both systems showed significant shifts during...
Introduction: Although non-contrast enhanced CT (NCCT) is commonly used in emergency rooms and may be utilized to determine the extent of ischemic changes, its limited agreement between different raters prevents widespread use NCCT deciding whether provide reperfusion therapies patients with suspected acute stroke (AIS). Therefore, this study aimed develop an automated approach for evaluating infarction AIS using NCCT. Methods: This multi-center retrospective included who presented within 24...
Bumblebees play crucial roles as pollinators in both natural agricultural and ecological systems. Their health overall fitness are significantly affected by the gut microbiota, which can maintain intestinal homeostasis hosts regulating their nutritional metabolism. However, information about diversity of microbiota related functional changes during artificial rearing native species is currently limited. This study investigated dynamic remodeling Chinese bumblebee Bombus lantschouensis under...
Abstract The present study aimed to investigate the protective effects of salidroside (SAL) on 1‐methyl‐4‐phenylpyridinium (MPP + )‐induced PC12 cell model for Parkinson's disease. cells were pretreated with SAL in different concentrations and then exposed MPP . To evaluate cytotoxicity, survival rate was tested by 3‐(4,5‐dimethylthiazol‐2‐yl)‐2,5‐dimethyltetrazolium bromide (MTT) assay apoptosis via flow cytometry Western blot. Reactive oxygen species (ROS), glutathione (GSH),...
Quantification of potential consequences associated with the use epidural analgesia during labor could help to improve safety and quality delivery care for parturient women.To evaluate association between neonatal infection in a large cohort women.This propensity score-matched study was conducted at university-affiliated hospital Shanghai, China. Women full-term pregnancy undergoing vaginal January 2013 October 2018 were included study. Parturient women who parous, experiencing premature...
Ischemic stroke is a destructive cerebrovascular disorder related to oxidative stress; NOX2 major source for ROS production; and miR-126a-5p involved in several diseases, such as abdominal aortic aneurysm. We investigated the role of regulating ischemic stroke. MiR-126a-5p were examined brains rats subjected cerebral ischemia/reperfusion (I/R) by RT-PCR Western blot. agomir was delivered examine effects on I/R injury. The neurological deficit, infarct volume, brain water content evaluated....
Human breast milk is recognized as one of multiple important sources commensal bacteria for infant gut. Previous studies searched the bacterial strains shared between and feces by isolating performing strain-level genotyping, but only limited number were identified to colonize gut, including from Bifidobacterium, Staphylococcus, Lactobacillus, Escherichia/Shigella. Here, identify capable colonizing gut without interference origins other than or necessity analyze feces, normal chow-fed...
Primary objective: Edaravone, a potent scavenger of hydroxyl radicals, has been used to treat acute cerebral ischemia, but its effects on intracerebral haemorrhage (ICH) are unknown. The present study tried understand the edaravone ICH in mice.Research design: Mice and control group were injected with collagenase induce ICH. given at 30 minutes, 24 hours 48 after induction ICH.Methods procedures: At 72 surgery, mice scored neurologically by 28-point neurological scoring system. haematoma...
Abstract Gastrointestinal dysfunction is the main nonmotor characteristic of Parkinson disease (PD), manipulation gastrointestinal function by altering gut-brain axis a potentially novel entry point for treatment PD. Acupuncture has been reported to confer beneficial effects in diseases. Therefore, this study aimed explore and mechanism acupuncture on pathophysiology A PD mouse model was established rotenone, electroacupuncture used regulate function. Rotenone found induce types brain...
We assessed neurological outcomes, infarct volume, and the expression of nestin caspase-3 in hippocampal dentate gyrus following middle cerebral artery occlusion (MCAO) followed by reperfusion, with mild hypothermia (MH) treatment at onset ischemia a MCAO rat model. Reperfusion began 2 hours after model was set-up. MH maintained for 4 hours. evaluated deficit score, brain volumes, along immunohistochemical staining sub-granular zone injured hemisphere on 1st, 3rd, 7th, 14th day ischemia....
Abstract Background Traumatic lymphatic leakage is a rare but potentially life-threatening complication. The purpose of this study was to introduce ultrasound-guided intranodal lymphangiography and embolisation techniques for postoperative in patients with cancer. Methods From January 2018 through June 2020, seven cancer (three males, four females, aged 59–75 years [mean 67.57 ± 6.11 years]) developed after abdominal or pelvic surgery, drainage volumes ranging from 550 1200 mL per day....
Objective: To compare chronic obstructive pulmonary disease (COPD) mouse models established by two different methods-cigarette smoke (CS) exposure alone and CS combined with airway instillation of bacterial LPS. Methods: Male C57 mice were randomly divided into control group(CTL group), group (CS group) intra-tracheal LPS (LPS+CS according to the random number table, 8 rats in each group. After established, we measured lung function collected bronchoalveolar lavage fluid (BALF) detect...