A5033838577- Cannabis and Cannabinoid Research
- Cerebrovascular and Carotid Artery Diseases
- Tryptophan and brain disorders
- Sleep and related disorders
- Traumatic Brain Injury and Neurovascular Disturbances
- Sleep and Wakefulness Research
- Diet, Metabolism, and Disease
- Circadian rhythm and melatonin
- Gut microbiota and health
- Treatment of Major Depression
- Neuroendocrine regulation and behavior
- Autism Spectrum Disorder Research
- Forensic Toxicology and Drug Analysis
- Reservoir Engineering and Simulation Methods
- Dementia and Cognitive Impairment Research
- Advanced MRI Techniques and Applications
- Neurological Disorders and Treatments
- Moyamoya disease diagnosis and treatment
- Tea Polyphenols and Effects
- Neurological Disease Mechanisms and Treatments
- Stress Responses and Cortisol
- Health, psychology, and well-being
- Family and Disability Support Research
- Machine Learning in Healthcare
- Maternal Mental Health During Pregnancy and Postpartum
Eastern Health
2023-2024
Monash University
2023-2024
Swinburne University of Technology
2011-2024
Background Understanding how vascular and metabolic factors impact on cognitive function is essential to develop efficient therapies prevent treat losses in older age. Cerebral rate of oxygen (CMRO2), cerebral blood flow (CBF) venous oxygenation (Yv) comprise key physiologic processes that maintain optimum functioning neural activity. Changes these parameters across the lifespan may precede neurodegeneration contribute age-related decline. This study examined differences metabolism between...
Cerebrovascular reactivity (CVR) reflects the response of brain blood vessels to vasoactive stimuli, such as neural activity. The current research assessed age-related changes in regional CVR 5% CO2 inhalation younger (n = 30, range: 21-45 years) and older 29, 55-75 adults, contribution cognitive performance using blood-oxygen-level dependent contrast imaging (BOLD) functional magnetic resonance (fMRI) at 3T field strength. was measured by inducing hypercapnia a block-design paradigm under...
As cannabinoid-based medications gain popularity in the treatment of refractory medical conditions, it is crucial to examine neurocognitive effects commonly prescribed products ensure associated safety profiles. The present study aims investigate acute a standard 1 mL sublingual dose CannEpil®, medicinal cannabis oil containing 100 mg cannabidiol (CBD) and 5 Δ9-tetrahydrocannabinol (THC) on neurocognition, attention, mood. A randomised, double-blind, placebo-controlled, within-subjects...
Background: Medicinal cannabis products containing Δ9-tetrahydrocannabinol (THC) are increasingly accessible. Yet, policy guidelines regarding fitness to drive lacking, and cannabinoid-specific indexations of impairment underdeveloped. Aims: To determine the impact a standardised 1 mL sublingual dose CannEpil ® , medicinal oil 100 mg cannabidiol (CBD) 5 THC on simulated driving performance, relative placebo whether variations in vehicle control can be indexed by ocular activity. Methods: A...
Abstract Cannabidiol (CBD), a non-intoxicating compound derived from the cannabis plant, has garnered increasing attention as potential pharmacological therapeutic for autistic children. We conducted randomised, double-blind, placebo-controlled, crossover trial to understand whether oral CBD oil can improve outcomes this population, with primary focus on social relating outcomes, along anxiety and parental stress. A total of 29 children (18 male), aged 5 12 years (M = 9.62 years, SD 2.05),...
<title>Abstract</title> <bold>Background</bold> Methamphetamine Use Disorder (MAUD) is associated with major public heath burden worldwide, yet medication treatment options are lacking. For many patients, the first step in a episode admission to residential detoxification or rehabilitation unit for withdrawal, however unplanned early discharge common, and evidence suggests benefits may be short-lived. Pharmacotherapy candidates methamphetamine withdrawal have thus far failed show sufficient...