A5007180104- Enzyme Catalysis and Immobilization
- Microbial Metabolic Engineering and Bioproduction
- Fungal and yeast genetics research
- Chemical Synthesis and Analysis
- Organic Chemistry Cycloaddition Reactions
- Inorganic and Organometallic Chemistry
- Carbohydrate Chemistry and Synthesis
- Asymmetric Synthesis and Catalysis
- Crystallization and Solubility Studies
- Chemical Synthesis and Reactions
- Analytical Chemistry and Chromatography
- X-ray Diffraction in Crystallography
- Biofuel production and bioconversion
- Transgenic Plants and Applications
- Molecular Sensors and Ion Detection
- Chemical Reaction Mechanisms
- Synthesis and Catalytic Reactions
- Antimicrobial Peptides and Activities
- Oxidative Organic Chemistry Reactions
- Catalysis for Biomass Conversion
- Analytical Chemistry and Sensors
- Click Chemistry and Applications
- Glycosylation and Glycoproteins Research
- Crystal structures of chemical compounds
- Antimicrobial agents and applications
Universitat de València
2013-2024
Brown University
1999
Massachusetts Institute of Technology
1993
Laboratoire de Chimie Moléculaire et Thioorganique
1978
Abstract The specific interaction of a variety modified hevein domains to chitooligosaccharides has been studied by NMR spectroscopy in order assess the importance aromatic–carbohydrate interactions for molecular recognition neutral sugars. These mutant AcAMP2‐like peptides, which have 4‐fluoro‐phenylalanine, tryptophan, or 2‐naphthylalanine at key interacting positions, prepared solid‐phase synthesis. Their three‐dimensional structures, when bound chitin‐derived trisaccharide, deduced...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTransport of Adenine Mono- and Dinucleoside Monophosphates across Liquid Membranes Extraction Oligonucleotides with Synthetic CarriersCecilia Andreu, Amalia Galan, Kazuya Kobiro, Javier de Mendoza, Tae Kyo Park, Julius Jr. Rebek, Armando Salmeron, Nassim UsmanCite this: J. Am. Chem. Soc. 1994, 116, 12, 5501–5502Publication Date (Print):June 1, 1994Publication History Published online1 May 2002Published inissue 1 June...
Biocatalysis is a green and sustainable technology based on the use of natural substances to catalyze chemical reactions. Humans have been unconsciously using biocatalysis for thousands years produce food alcoholic beverages, but it only since 19th century that we begun understand its fundamentals enormous potential. In fact, advances in our knowledge enzymes metabolic pathways and, recent decades, introduction tools such as bioinformatics, DNA sequencing protein engineering made key...
The oxidation of iodomethane with dimethyldioxirane allows the generation stable neutral solutions hypoiodous acid in absence any trapping agent for iodide anion. Hypoiodous is trapped situ by addition to representative olefins give iodohydrines good yields. stereochemical study products shows anti-stereospecific nature iodohydroxylation reaction.
The reactivity of individual C--H bonds in the methyl(trifluoromethyl)dioxirane TFDO oxygenation stereogenic methylene groups conformationally homogeneous monosubstituted cyclohexanes (2) has been determined. unexpectedly high occurrence O-atom insertion into C--H(ax) suggests an plane trajectory attack while diastereoselectivity reaction is qualitatively interpreted on basis distinct hyperconjugative stabilization by substituent diastereomeric transition states due to long-range through...
Abstract The application of green chemistry concepts in catalysis has considerably increased recent years, and the interest using sustainable solvents chemical industry is growing. One proposals to fall line with this employ seawater as a solvent biocatalytic processes. This involves selecting halotolerant strains capable carrying out conversions presence salt concentrations found solution. Recent studies by our group have revealed belonging Debaryomyces Schwanniomyces for catalytic...
Antibiotic resistance is now a first-order health problem, which makes the development of new families antimicrobials an imperative. These compounds should ideally be inexpensive, readily available, highly active and non-toxic. Here we present results on antimicrobial activity series natural synthetic polyamines with different architectures (linear, tripodal macrocyclic) their derivatives containing oxygen aromatic functional groups 1,3-benzodioxol, ortho/para phenol or...
The epoxidation rate constants for the reaction of allylic and homoallylic primary quaternary ammonium salts with DMDO (1b) m-CPBA (2), as well stereochemical outcome these reactions, were determined. presence an ionic functional group in substrate complicates kinetic study reaction. However, k(0) can be determined from k(obs) values measured solutions different strengths. order magnitude is same salts, while react more than 10 times faster their counterparts. High syn-diastereoselectivity...
Tandem cycloaddition–enzymatic transesterification with pancreatic pig upase or the lipase from Candida ciclindracea carried out in ethyl, vinyl, isopropenyl acetate gives rise to optically active Diels–Alder type derivatives symmetrical precursors both high enantioselectivity and chemical yield.
Abstract The catalytic activity of complexes involving organic ligands and Lewis acids can be modulated by changing any their components. In this work we have studied the influence on stereoselectivity exerted counterion zinc salts employed as cocatalysts L ‐prolinamide in aldol condensations. structures been determined both solution solid state.
Antibiotic resistance is now a first-order health problem, which makes the development of new families antimicrobials imperative. These compounds should ideally be inexpensive, readily available, highly active, and non-toxic. Here, we present results our investigation regarding antimicrobial activity series natural synthetic polyamines with different architectures (linear, tripodal, macrocyclic) their derivatives oxygen-containing aromatic functional groups 1,3-benzodioxol, ortho/para...
The oxidation of 2-substituted adamantanes (2) with TFDO (1) is reported. data show a stereodifferentiation the chemical environments induced by remote electron-withdrawing substituents which produces remarkable Z/E diastereoselectivity in tertiary C(5)-H and C(7)-H bonds. results bell-shaped correlation between stereoselectivity substituent constant sigma(I), interpreted terms hyperconjugative stabilization diastereomeric transition states.