A5060159666- Multiple Sclerosis Research Studies
- Ultrasound and Hyperthermia Applications
- Advanced MRI Techniques and Applications
- Systemic Lupus Erythematosus Research
- RNA regulation and disease
- Ultrasound Imaging and Elastography
- COVID-19 diagnosis using AI
- Ultrasound in Clinical Applications
- Shoulder Injury and Treatment
- Peripheral Neuropathies and Disorders
- Hip and Femur Fractures
- Cerebrovascular and Carotid Artery Diseases
- Lower Extremity Biomechanics and Pathologies
- Bacterial Infections and Vaccines
- COVID-19 Clinical Research Studies
- Hip disorders and treatments
- Lanthanide and Transition Metal Complexes
- Shoulder and Clavicle Injuries
- Sepsis Diagnosis and Treatment
- Viral Infections and Immunology Research
- Gene expression and cancer classification
- Sports injuries and prevention
- Hemoglobinopathies and Related Disorders
- Radiation Dose and Imaging
- Neurogenetic and Muscular Disorders Research
OLVG
2017-2021
University College London
2018
Amsterdam UMC Location Vrije Universiteit Amsterdam
2011-2017
Amsterdam Neuroscience
2017
The relevance of cortical grey matter pathology in multiple sclerosis has become increasingly recognized over the past decade.Unfortunately, a large part lesions remain undetected on magnetic resonance imaging using standard field strength.In vivo studies have shown improved detection by higher strengths up to 7 T.So far, systematic histopathological verification ultra-high pulse sequences been lacking.The aim this study was determine sensitivity T versus 3 for directly comparing them...
Developmental dysplasia of the hip comprises a broad spectrum abnormalities in development, variable severity. Besides physical examination, ultrasound is preferred imaging modality for screening developmental children aged younger than six months. The Graf method most widely used technique infant hips; stepwise approach will be shown this article. Furthermore, process dynamic explained as well use transinguinal infants wearing spica cast. There no consensus on best way to screen hip, which...
<h3>BACKGROUND AND PURPOSE:</h3> 7T MR imaging has led to improved detection and classification of cortical MS lesions, mainly based on T2*-weighted gradient-echo sequences. Depiction GM by using the recommended protocol not yet been investigated at 7T. We aimed investigate prospectively which sequence for clinical use highest value 7T, in terms WM lesion detection. <h3>MATERIALS METHODS:</h3> Thirty-seven patients with (mean age, 43.8 years; 25 women) 7 healthy controls 40.4 5 underwent...
Background: Iron accumulation in deep grey matter (GM) structures is a consistent finding multiple sclerosis (MS) patients. This study focused on the identification of independent determinants iron using R 2 * mapping. Subjects and methods: Ninety-seven MS patients 81 healthy controls were included this multicentre study. mapping was performed 3T MRI systems. *in GM corrected for age related to disease duration, disability, T lesion load brain volume. Results: Compared controls, increased...
<h3>Objective</h3> In the work-up of patients presenting with a clinically isolated syndrome (CIS), 3T MRI might offer higher lesion detection than 1.5T, but it remains unclear whether this affects fulfilment diagnostic criteria for multiple sclerosis (MS). <h3>Methods</h3> We recruited 66 CIS within 6 months from symptom onset and 26 healthy controls in MS centers. All participants underwent 1.5T brain spinal cord at baseline according to local optimized protocols MAGNIMS guidelines....
Background: Compared to 1.5 T, 3 T magnetic resonance imaging (MRI) increases signal-to-noise ratio leading improved image quality. However, its clinical relevance in clinically isolated syndrome suggestive of multiple sclerosis remains uncertain. Objectives: The purpose this study was investigate how MRI affects the agreement between raters on lesion detection and diagnosis. Methods: We selected 30 patients 10 healthy controls from our ongoing prospective multicentre cohort. All subjects...
Purpose The relaxation rate constant has been suggested as a sensitive measure for iron accumulation. aim of this multi‐center study was to assess the inter‐scanner and inter‐subject variability mapping investigate relationship between brain volume in specific structures. Methods performed 81 healthy subjects seven centers using different 3 T systems. calculated from dual‐echo gradient echo sequence assessed several deep gray matter by means coefficient variation before after correcting age....
In the coronavirus disease 2019 (COVID-19) pandemic, rapid clinical triage is crucial to determine which patients need hospitalisation. We hypothesised that chest computed tomography (CT) and alveolar-arterial oxygen tension ratio (A-a) gradient may be useful these patients, since they reflect severity of pneumonia-associated ventilation/perfusion abnormalities.A retrospective analysis was performed in 235 consecutive suspected for COVID-19. The diagnostic protocol included low-dose CT...
Background: Rockwood I and II acromioclavicular joint injuries are generally treated nonoperatively. The long-term outcome is considered to be good but has not yet been properly investigated. Purpose: To assess the after nonoperative therapy for regarding functional radiologic outcome. Study Design: Cohort study; Level of evidence, 3. Methods: Eligible patients visited emergency department between January 2003 December 2015 were ≥16 years old at time presentation. main study parameters...
To determine the prevalence and spectrum of incidental findings (IFs) identified in patients undergoing chest CT as a primary triage tool for COVID-19.In this study 232 were triaged our COVID-19 Screening Unit by means (March 25-April 23, 2020). Original radiology reports evaluated retrospectively description IFs, which defined any finding report not related to purpose scan. Documented IFs categorized according clinical relevance into minor potentially significant anatomical location...
BackgroundStandardized consensus-based radiological reports for shoulder instability may improve clinical quality, reduce heterogeneity and workload. Therefore, the aim of this study was to determine important elements x-ray, MRA CT report, extent variability MRI views settings.MethodsAn expert panel musculoskeletal radiologists orthopedic surgeons recruited in a three-round Delphi design. Important were identified report setting. These rated on 0-9 Likert scale. High defined as at least one...
Fazit Im Vergleich zu bisherigen MRT-Techniken konnte in dieser Studie mit dem kombinierten T2-gewichteten 7-T-FLAIR*-MRT, das ohne Kontrastmittel auskommt, die Differenzierung zwischen multipler Sklerose und Gefäßläsionen verbessert werden, so Autoren. Zur der Läsionen trugen Lokalisation, unregelmäßige Randbezirke sowie Zentralgefäße MS-Läsionen bei, hoher Auflösung dargestellt werden konnten.