A5078741108- Judicial and Constitutional Studies
- American Constitutional Law and Politics
- Law in Society and Culture
- Legal Systems and Judicial Processes
- Law, Rights, and Freedoms
- Legal Education and Practice Innovations
- Legal Language and Interpretation
- Pregnancy and preeclampsia studies
- Global Maternal and Child Health
- European and International Law Studies
- Intellectual Property Law
- Legal and Constitutional Studies
- Political Systems and Governance
- Comparative and International Law Studies
- Lexicography and Language Studies
- CRISPR and Genetic Engineering
- Hong Kong and Taiwan Politics
- Freedom of Expression and Defamation
- Birth, Development, and Health
- Ombudsman and Human Rights
- Commonwealth, Australian Politics and Federalism
- Hate Speech and Cyberbullying Detection
- International Law and Human Rights
- linguistics and terminology studies
- Mathematical and Theoretical Epidemiology and Ecology Models
National University of Science and Technology
2010-2023
University of Liverpool
2023
University of Sheffield
2013-2022
University of Dundee
2016-2018
Brown University
2013-2017
Liverpool Hope University
2016-2017
Academia Sinica
2012-2014
Pennsylvania State University
2013
University of Stirling
2011-2012
Emory University
2011
Significance Most eukaryotic genomes contain abundant transposable elements (TEs), mobile DNA that can replicate and move within the genome. Because of deleterious nature active TEs, cells have mechanisms to suppress prevent TE activation, including formation repressive heterochromatin. In this report, we show many TEs become activated with age in Drosophila , activation is prevented by dietary restriction, an intervention known extend life span. We also blocked genetic manipulations...
Abstract In gonadal tissues, the Piwi-interacting (piRNA) pathway preserves genomic integrity by employing 23–29 nucleotide (nt) small RNAs complexed with argonaute proteins to suppress parasitic mobile sequences of DNA called transposable elements (TEs). Although recent evidence suggests that piRNA may be present in select somatic cells outside gonads, role a non-gonadal is not well characterized. Here we report functional adult Drosophila fat body including presence effector protein Piwi...
Abstract Generations of citizens have successfully used civil disobedience to enact positive lasting change in their societies. In some places, such as the UK and elsewhere, it is considered a ‘tradition’. But recent instances disobedience—especially relation climate campaigners—have brought forward numerous challenges, which lie awkwardly with liberal values. particular, lack fidelity existing political system, attempts at evading punishment robust challenges court authority can make...
Journalists and commentators have dismissed acronym-titled laws like the SAFE Act (Secure Access to Firearms Enhancement Act) slogan-based political action committee (“PAC”) names Americans for America as window dressing concocted by uncreative operatives. Beyond fact that law titles PAC become punching bags in press, they share another quality: both appear with frequency ads about ballot initiatives sometimes on ballots themselves. Because of their salience election voting scenarios, been...
Abstract The growing threat to liberal democracy worldwide is, in many ways, a political party threat. Recent years have witnessed the rise of range authoritarian populist, illiberal, far-right, nativist, and extremist parties. Some entered government countries including Hungary, Poland, Austria, Italy. Germany’s Alternativ für Deutschland (AfD) is now main parliamentary opposition. Beyond Europe we see democratic structures threatened or incrementally dismantled through subversion an...
This paper presents a methodology which has been used to address two ubiquitous problems of practising digital forensics in law enforcement, the ever increasing data volume and staff exposure disturbing material. It discusses how New South Wales Police Force, State Electronic Evidence Branch (SEEB) implemented "Discovery Process". Using random sampling files applying statistical estimation results, branch able reduce backlogs from three months 24 h. The process added advantage reducing child...
Severe preeclampsia and eclampsia have dire consequences for both maternal neonatal health. The objective of this study was to identify determinants adverse perinatal outcomes in severe eclampsia. Binary logistic regression showed the following were significantly associated with outcomes; mothers who had a baby born at 27–29+6 weeks gestation 8 times more likely be compared gave birth 37–39+6 weeks' (OR 8.187, 95% CI 1.680–39.911, p = 0.02), holding other variables constant. Platelet count...
Glucocorticoids influence cell proliferation and differentiation in the lung. We examined expression of glucocorticoid receptor (GR) gene urethan-induced mouse lung tumors transformed lines to determine whether any altered responsiveness these steroids is involved neoplastic development some tumors. find that a GR mRNA similar size amount expressed both normal The K-ras activated adenomas lines. Both alveolar papillary express slightly elevated levels ofH-ras mRNA, but variable c-myc mRNA....
Background Strains from a collection of Drosophila GFP protein trap lines express in the normal tissues where endogenous is present. This can be used to screen for proteins distributed nucleus non-uniform pattern. Methodology/Principal Findings We analyzed four that show peripheral or punctate nuclear staining. One these affects an uncharacterized gene named CG11138. The CG11138 shows distribution periphery similar insulator but does not co-localize with known insulators. Interestingly,...
A new method is described for the numerical solution of Timoshenko integral equation impulsive constant force between two elastic impacting bodies. The computationally fast and gives very accurate results. Its use illustrated by treating case central impact a steel sphere onto simply supported circular plate.
Double Reading of Barium Enemas: Is It Necessary?Cheri L. Canon1, J. Kevin Smith1, Desiree E. Morgan1, Brian C. Jones1, Sean Fell1, Philip Kenney1, Dino Ferrante2, Mark Lockhart1, Andrew O. Westfall3 and Robert Koehler1Audio Available | Share
Hypertensive disorders in pregnancy are a leading cause of maternal and perinatal morbidity mortality, especially low-resource settings. Identifying mothers babies at greatest risk complications would enable intervention to be targeted those most likely benefit from them. However, current prediction models have wide range sensitivity (42-81%) specificity (87-92%) indicating that improvements needed. Furthermore, no predictive been developed or evaluated Zimbabwe. This proposal describes...
Abstract Objectives Stillbirth remains a global public health issue; in low-resource settings stillbirth rates remain high (>12 per 1,000 births target of Every Newborn Action Plan). Preeclampsia is major risk factor for stillbirths. This study aimed to determine the prevalence and factors amongst women with severe preeclampsia at Mpilo Central Hospital. Methods A retrospective cross-sectional was conducted from 01/01/2016 31/12/2018 Hospital, Bulawayo, Zimbabwe. Multivariable logistic...
A hybrid matheuristic algorithm is formulated by combining Grotschel–Holland and Max–Min Ant System algorithms to solve design network engineering problems. In the majority of our examples, seems promising. The has ability increase exploration it maximizes exploitation various solutions certainty exact methods find a solution. Further, recommended study direction improve higher-order polynomial type problems efficiently.