A5064828982- Acute Lymphoblastic Leukemia research
- Childhood Cancer Survivors' Quality of Life
- Lymphoma Diagnosis and Treatment
- Neutropenia and Cancer Infections
- Viral-associated cancers and disorders
- Acute Myeloid Leukemia Research
- Tumors and Oncological Cases
- Neuroblastoma Research and Treatments
- Renal and related cancers
- Sarcoma Diagnosis and Treatment
- Chronic Lymphocytic Leukemia Research
- Sepsis Diagnosis and Treatment
- Cancer therapeutics and mechanisms
- Neonatal and Maternal Infections
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Adolescent and Pediatric Healthcare
- Lung Cancer Research Studies
- History of Education Research in Brazil
- Healthcare Regulation
- Science and Education Research
- Chronic Myeloid Leukemia Treatments
- Eosinophilic Disorders and Syndromes
- Cutaneous lymphoproliferative disorders research
- Parasitic Infections and Diagnostics
- Food, Nutrition, and Cultural Practices
Hospital São Rafael
1992-2023
Universidade Tiradentes
2019
Sociedade Brasileira de Oncologia Clínica
2003-2015
Centro Infantil Boldrini
2009
Hospital Santa Marcelina
2009
Brazilian Academy of Sciences
2007
Pathodiagnostik Berlin
1996
Freie Universität Berlin
1996
Fundação Bahiana de Infectologia
1994
In 1988, we formed a consortium of Brazilian institutions to develop uniform standards for the diagnostic assessment and multidisciplinary treatment children adolescents with germ cell tumors. We also implemented first childhood tumor protocol, GCT-91, evaluating two-agent chemotherapy cisplatin etoposide (PE). now report on clinical characteristics survival tumors treated this protocol.From May 1991 April 2000, 115 patients (106 assessable patients) were enrolled onto protocol diagnosis...
This study was to determine the prevalence and characteristics of osteoarticular manifestations on initial clinical presentation acute leukemias (ALs) childhood in state Bahia, Brazil.This retrospective assessed medical records 406 patients with AL from January 1995 December 2004.Acute lymphocytic leukemia (ALL) diagnosed 313 (77.1%) myeloid (AML), 93 (22.9%) patients, including 241 males (59.4%) 165 females (40.6%). Age ranged 9 months 15 years (average: 6.18 y). The most common presenting...
A 7-month-old boy had a giant pigmented lesion involving the trunk and thighs that exhibited many hyperpigmented hairy verrucous nevi. One of nevi ulcerated on histological examination consisted pleomorphic rhabdomyosarcoma cells stained for muscle-specific actin (HHF-35), desmin, myoglobin. Around tumor, in dermis, benign nevus were observed. The occurrence malignant tumors, other than melanoma, is rarely described.
SIL-TAL1 fusion gene and the ectopic expression of HOX11L2 are common molecular abnormalities in T-cell acute lymphoblastic leukemia (T-ALL). To verify their influence on outcome, we analyzed a Brazilian pediatric T-ALL series cases. One hundred ninety two children, age ranged 0–21 years old, were consecutively diagnosed treated. Reverse transcriptase-polymerase chain reaction (RT-PCR) technique was used to identify alterations. Kaplan–Meyer method applied estimate overall survival. The most...
Maintenance therapy is an important phase of the childhood ALL treatment, requiring 2-year long adherence patients and families. Weekly methotrexate with daily 6-mercaptopurine (6MP) constitutes backbone maintenance therapy. Reduction in could overweight problems related poverty children living limited-income countries (LIC).To compare, prospectively, EFS rates treated according to two regimens: 18 vs. 24 months duration.From October 1993 September 1999, 867 consecutive untreated <18 years...
<p class="MsoNormal" style="text-align: justify;"><strong>Introdução:</strong> Crianças constituem um dos principais grupos de risco infecções por <em>Giardia duodenalis</em> e outros enteroparasitos. A infecção é geralmente assintomática ou pode evoluir para diarreia aguda tornar-se crônica, resultando em perda peso retardo no crescimento. Em crianças com tumores malignos, a parasitária seguir curso severo mesmo resultar morte....
We describe the demographic and biological characteristics of 1,459 children with acute leukemia in Brazil to compare effect immunophenotypic differences environmental factors that might be involved etiology lymphoblastic (ALL). Combined morphological immunological classifications were available for 96% cases. Of these, 55% B cell precursor ALL comprising pro-B c-ALL, 15% T-ALL 1.6% mature B-ALL. The proportion Bp differed by race 59% whites being Bp-ALL 60.7% non-whites T-ALL. Further...
OBJETIVOS: Fornecer subsídios à abordagem diagnóstica, profilática e terapêutica da neutropenia febril sepse em criança com doença oncológica, dando especial atenção aos novos protocolos diretrizes. FONTES DE DADOS: Revisão de literatura científica utilizando uma busca bibliográfica eletrônica nas páginas do MEDLINE, Medscape, SciELO, Google, Cochrane PubMED as palavras-chave febrile, neutropenic, cancer, children, sepse, intensive, care. Foram selecionados artigos publicados entre 1987...
Abstract: An 8‐year‐old boy was seen with a cutaneous Ki‐1 anaplastic, large cell lymphoma multiple lesions. Some of the lesions showed spontaneous regression. During more than seven years disease no systemic Involvement observed, but recurrent, self‐healing did appear. Histopathologic examination five revealed variety findings, from an inflammatory infiltrate to highly anaplastic pattern. The neoplastic cells expressed and leukocyte common antigens. Ultrastructurally, those ruffled...
A case of a 6 year old child, with pleomorphic rhabdomyosarcoma involving simultaneously the leg muscles and kidney is reported. The renal tumor distorted pyelocalycial system Wilms' was clinical diagnosis. authors discuss on possible primary site tumor.
É apresentado um caso de tumor Wilms bilateral em criança ano. O primeiro tumor, rim direito, tinha o aspecto histopatológico clássico e apenas 10 % sua área era representada por fibras musculares estriadas tipo embrionário. do esquerdo manifestou-se quatro meses após diagnóstico constituído quase que exclusivamente tecido muscular estriado A está agora com anos vive normalmente dois terços rim.
O objetivo desta pesquisa foi investigar as características sócio-demográficas e clínico-patológicas dos linfomas não-Hodgkin (LNH) em crianças adolescentes no estado da Bahia. Do ponto de vista metodologia, trata-se estudo descritivo com dados secundários 111 pacientes LNH, procedentes dois centros referência. Critérios inclusão: idade <20 anos, residência na Bahia admissão período janeiro de2000 a dezembro 2005, diagnóstico anátomo-patológico LNH. Obtiveram-se os seguintes resultados:...