A5080595847- Child and Adolescent Psychosocial and Emotional Development
- Mental Health Treatment and Access
- Health Systems, Economic Evaluations, Quality of Life
- Maternal Mental Health During Pregnancy and Postpartum
- Health disparities and outcomes
- Obesity, Physical Activity, Diet
- Health Policy Implementation Science
- Eating Disorders and Behaviors
- Global Health Care Issues
- Digital Mental Health Interventions
- Obesity and Health Practices
- Substance Abuse Treatment and Outcomes
- Primary Care and Health Outcomes
- Family Caregiving in Mental Illness
- Mental Health Research Topics
- Intergenerational Family Dynamics and Caregiving
- Nutritional Studies and Diet
- Global Public Health Policies and Epidemiology
- Adolescent and Pediatric Healthcare
- Bipolar Disorder and Treatment
- Behavioral Health and Interventions
- Healthcare innovation and challenges
- Dermatology and Skin Diseases
- Treatment of Major Depression
- demographic modeling and climate adaptation
Monash University
2022-2025
Queensland Centre for Mental Health Research
2015-2024
The University of Queensland
2015-2024
Brown University
2024
Sungshin Women's University
2024
Curtin University
2023
Deakin University
2018-2022
University of California, San Francisco
2021-2022
HTG Molecular Diagnostics (United States)
2022
Mayo Clinic in Arizona
2011-2020
MUC1 is overexpressed and aberrantly glycosylated in more than 60% of pancreatic ductal adenocarcinomas. The functional role cancer has yet to be fully elucidated due a dearth appropriate models. In this study, we have generated mouse models that spontaneously develop adenocarcinoma (KC), which are either Muc1-null (KCKO) or express human (KCM). We show KCKO mice significantly slower tumor progression rates secondary metastasis, compared with both KC KCM. Cell lines derived from tumors less...
School-based psychological interventions encompass: universal targeting youth in the general population; and indicated with subthreshold depression. This study aimed to: (1) examine population cost-effectiveness of delivering prevention to aged 11-17 years via primary secondary schools Australia; (2) compare comparative these using face-to-face internet-based delivery mechanisms.We reviewed literature on depression identify all that would be suitable for implementation Australia had evidence...
BackgroundReducing suicides is a key Sustainable Development Goal target for improving global health. Highly hazardous pesticides are among the leading causes of death by suicide in low-income and middle-income countries. National bans acutely toxic highly have led to substantial reductions pesticide-attributable across several This study evaluated cost-effectiveness implementing national reduce burden pesticide suicides.MethodsA Markov model was developed examine costs health effects ban...
<h3>Importance</h3> Research has highlighted associations between atopic dermatitis (AD) and mental health conditions in adults. However, literature on the development of comorbidities children is limited despite large burden pediatric AD worldwide. <h3>Objective</h3> To examine association internalizing behaviors symptoms depression at multiple points across childhood adolescence to explore potential mediating factors, including asthma/rhinitis, sleep, inflammation. <h3>Design, Setting,...
Public health guidelines recommend delaying the initiation age for alcohol. However, causal link between age-at-first-drink (AFD) and future alcohol use in young adulthood is uncertain. This study examined association AFD alcohol-related outcomes at 20 years using an Australian sample.
Interventions targeting portion size and energy density of food beverage products have been identified as a promising approach for obesity prevention. This study modelled the potential cost-effectiveness of: package cap on single-serve sugar sweetened beverages (SSBs) >375 mL (package cap), product reformulation to reduce content packaged SSBs (energy reduction). The each intervention was 2010 Australia population using multi-state life table Markov model with lifetime time horizon....
The Health Star Rating (HSR) system is a voluntary front-of-pack labelling (FoPL) initiative endorsed by the Australian government in 2014. This study examines impact of HSR on pre-packaged food reformulation measured changes energy density between products with and without HSR. cost-effectiveness was modelled using proportional multi-state life table Markov model for 2010 population. We evaluated scenarios which implemented mandatory basis (i.e., uptake across 6.7% 100% applicable products,...
Failure of drainage systems leads to urban flooding; therefore, structural measures such as the installation additional facilities, including pump stations and detention reservoirs, have been adopted in past prevent mitigate flooding. These measures, however, are costly time consuming. To maximize flood mitigation efficiency, it is essential also implement non-structural effective operation facilities. In this study, we propose a new cooperative scheme for that involves linking centralized...
Parenting programmes are the recommended treatments of conduct disorders (CD) in children, but little is known about their longer term cost-effectiveness. This study aimed to evaluate population cost-effectiveness one most researched evidence-based parenting programmes, Triple P-Positive Programme, delivered a group and individual format, for treatment CD children. A population-based multiple cohort decision analytic model was developed estimate cost per disability-adjusted life year (DALY)...
Introduction: Despite recent clinical and research interest, medical use of psychedelics has not been legalised in most jurisdictions. The Australian Therapeutic Goods Administration rescheduled methylenedioxymethamphetamine (MDMA) July 2023 to permit authorised prescribing MDMA for Post-traumatic Stress Disorder (PTSD) outside the trial setting. Objective: This manuscript describes development Clinical Practice Guideline on MDMA-assisted psychotherapy (MDMA-AP) PTSD. Methods: will be...
A detention reservoir is one of the most effective engineered solutions for flood damage mitigation in urban areas. Detention facilities are constructed to temporarily store storm water and then slowly drain when peak period has passed. This delayed drainage may coincide with upstream floods aggravate risk downstream. Optimal operation design needed improve performance reservoirs reduction. study couples hydrologic simulation software (EPA-SWMM) an evolutional optimizer (extraordinary...
Background Mental health treatment rates are increasing, but the burden of disease has not reduced. Tools to support efficient resource distribution required. Aim To investigate whether a person-centred e-health (Target-D) platform matching depression care symptom severity prognosis can improve depressive symptoms relative usual care. Design and setting Stratified individually randomised controlled trial in 14 general practices Melbourne, Australia, from April 2016 February 2019. In total,...
Suicide is the leading cause of death among young Australians, accounting for one-third all deaths in those under 25. Schools are a logical setting youth suicide prevention activities, with universal, selective and indicated approaches demonstrating efficacy. Given that international best practice recommends programmes combine these approaches, to date this has not been done school settings, study aims evaluate programme incorporating components schools.
Preventing the occurrence of depression/anxiety and suicide during adolescence can lead to substantive health gains over course an individual person's life. This study set out identify expected population-level costs impacts implementing universal indicated school-based socio-emotional learning (SEL) programs in different country contexts.A Markov model was developed examine effectiveness delivering SEL prevent onset deaths among adolescents. Intervention were measured healthy life years...
Planning mental health carer services requires information about the number of carers, their characteristics, service use and unmet support needs. Available Australian estimates vary widely due to different definitions illness types carers included. This study aimed provide a detailed profile using nationally representative household survey.The characteristics care recipients, caring hours tasks provided, needs were derived from national 2012 Survey Disability, Ageing Carers. Co-resident...