- Climate Change and Health Impacts
- Heavy Metal Exposure and Toxicity
- Air Quality and Health Impacts
- Trace Elements in Health
- Sepsis Diagnosis and Treatment
- Inflammatory Biomarkers in Disease Prognosis
- Acute Ischemic Stroke Management
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Heavy metals in environment
- Cardiac, Anesthesia and Surgical Outcomes
- Heart Failure Treatment and Management
- Cancer, Lipids, and Metabolism
- Renal function and acid-base balance
- Intensive Care Unit Cognitive Disorders
- Cardiovascular Health and Disease Prevention
- Cancer Risks and Factors
- Blood Pressure and Hypertension Studies
- Luminescence and Fluorescent Materials
- Lipoproteins and Cardiovascular Health
- Adipokines, Inflammation, and Metabolic Diseases
- Acute Myocardial Infarction Research
- Acute Kidney Injury Research
- Anesthesia and Sedative Agents
- Chronic Kidney Disease and Diabetes
- Cholangiocarcinoma and Gallbladder Cancer Studies
Chinese Academy of Medical Sciences & Peking Union Medical College
2020-2025
Central South University
2012-2025
Xiangya Hospital Central South University
2025
Second Affiliated Hospital of Zhejiang University
2025
The First People's Hospital of Changde
2015-2024
Huazhong University of Science and Technology
2024
Soochow University
2021-2024
University of Shanghai for Science and Technology
2024
Weatherford College
2020-2024
Sichuan University
2023
This paper proposed a natural gelatin capped mesoporous silica nanoparticles (MSN@Gelatin) based pH-responsive delivery system for intracellular anticancer drug controlled release. In this system, the gelatin, proteinaceous biopolymer derived from processing of animal collagen, was grafted onto MSN to form capping layer via temperature-induced gelation and subsequent glutaraldehyde mediated cross-linking, resulting in coated MSN. At neutral pH, could effectively prohibit release loaded...
This study targeted elucidating the intricate correlation of blood urea nitrogen (BUN)-to-albumin (BUN/Alb) ratio with adverse outcomes (AOs) at 3-month in acute ischemic stroke (AIS) cases within a Korean cohort.
The anion gap (AG) has been linked to the prognosis of many cardiovascular disorders. However, correlation between albumin-corrected (ACAG) and 30 d all-cause mortality intensive care patients with acute myocardial infarction (AMI) is unclear. Furthermore, owing lack studies, it also unknown whether ACAG more accurate than AG in predicting AMI.
Diminished insulin action in the vasculature may contribute to development of cardiovascular diseases diabetes. We have studied insulin's effects on phosphatidylinositol (PI) 3-kinase pathway arterial smooth muscle cells (SMCs) and its inhibition by endothelin (ET)-1, a potent vasoactive hormone reported be elevated resistance other vascular diseases. ET-1 increased level serine phosphorylation receptor beta subunit but both tyrosine substrate (IRS)-2. Pretreatment with (10 nmol/l) inhibited...
We aimed to investigate whether urinary metal mixtures are associated with the homeostasis of inflammatory mediators in middle-aged and older adults. A four-visit repeated-measures study was conducted 98 adults from five communities Beijing, China. Only one person lost follow-up at third visit. Ultimately, 391 observations were included analysis. The concentrations 10 metals measured each visit using inductively coupled plasma mass spectrometry (ICP-MS) a limit detection (LOD) ranging 0.002...
Red cell distribution width (RDW) and albumin level are linked to adverse outcomes in patients with acute myocardial infarction (AMI). Nonetheless, it remains unknown whether the RDW/albumin ratio (RAR) is associated short-term prognosis of AMI. Using a large cohort, we aimed explore association between RAR in-hospital all-cause mortality intensive care unit (ICU) AMI.The patients' data analyzed this retrospective cohort investigation were obtained from eICU Collaborative Research Data...
We aimed to investigate the relationship between serum anion gap (AG) and all-cause mortality in patients with acute pancreatitis (AP) intensive care units (ICUs).In this retrospective cohort analysis, data of AP were extracted from Medical Information Mart for Intensive Care database (version III). collected maximum AG value within first 24 hours ICU admission. The main outcome was 90-day mortality. A multivariate Cox proportional hazard regression model used examine association restricted...