Usman Aziz

ORCID: 0000-0003-2378-340X
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About
Contact & Profiles
Research Areas
  • Plant Molecular Biology Research
  • Plant nutrient uptake and metabolism
  • Molecular Biology Techniques and Applications
  • Plant Stress Responses and Tolerance
  • CRISPR and Genetic Engineering
  • Plant tissue culture and regeneration
  • Animal Genetics and Reproduction
  • Photosynthetic Processes and Mechanisms
  • Seed Germination and Physiology
  • Plant Genetic and Mutation Studies
  • Plant Parasitism and Resistance
  • Lipid metabolism and biosynthesis
  • Renal cell carcinoma treatment
  • Asymmetric Synthesis and Catalysis
  • Chemical Synthesis and Analysis
  • Cancer Immunotherapy and Biomarkers
  • Plant Gene Expression Analysis
  • Environmental DNA in Biodiversity Studies
  • Food composition and properties
  • Plant responses to water stress
  • Advanced Cellulose Research Studies
  • Soybean genetics and cultivation
  • Plant-Microbe Interactions and Immunity
  • Pancreatic and Hepatic Oncology Research
  • PI3K/AKT/mTOR signaling in cancer

Islamia University of Bahawalpur
2023-2024

Northwest A&F University
2018-2023

Northwestern Polytechnical University
2021-2022

Exelixis (United States)
2022

Robert Bosch (Germany)
2021

Micron (United States)
2021

Micron Biomedical (United States)
2021

Harm Reduction Services
2021

Agriculture and Forestry University
2020

University of Pennsylvania
2011

The present study was carried out to investigate the beneficial role of exogenous application salicylic acid (1 mM SA) and nitric oxide (100 μM NO) in preventing oxidative damage Vigna angularis triggered by salinity stress. Salinity NaCl) stress reduced growth, biomass accumulation, chlorophyll synthesis, photosynthesis, gas exchange parameters, photochemical efficiency (Fv/Fm) significantly. Exogenous SA NO affective enhancing these growth photosynthetic parameters. relative water content...

10.3390/biom10010042 article EN cc-by Biomolecules 2019-12-26

Pot experiments were conducted to investigate the probable beneficial role of individual as well combined application kinetin (50 μM Kn) and spermidine (200 Spd) on Vigna angularis under cadmium (Cd) stress. Cd treatment reduced growth by declining content chlorophylls carotenoids, photosynthesis, gas exchange parameters. Exogenously, Kn Spd enhanced photosynthetic parameters up-regulated antioxidant system improving activities enzymes non-enzymatic components. In addition, resulted in...

10.3390/biom10010147 article EN cc-by Biomolecules 2020-01-16

Cell cycle progression and the phytohormones auxin abscisic acid (ABA) play key roles in primary root growth, but how ABA mediates transcription of cell cycle-related genes mechanism crosstalk between requires further research. Here, we report that inhibits growth by regulating INSENSITIVE4 (ABI4)-CYCLIN-DEPENDENT KINASE B2;2 (CDKB2;2)/CYCLIN B1;1 (CYCB1;1) module-mediated as well biosynthesis Arabidopsis (Arabidopsis thaliana). induced ABI4 tip, abi4 mutant showed an ABA-insensitive...

10.1093/plphys/kiac407 article EN PLANT PHYSIOLOGY 2022-09-01

The rhizosphere and phyllosphere are the below- above-ground microbial ecosystems of plants. Interactions between shape plant-microbiome environment, which carries out functions from seedling development to reproductive growth. community germinating seeds associated soil is termed spermosphere. It represents numerous microorganisms that, by modulating seed exudates, may impact establishment phyllosphere. In this review, we first explore recent understanding plant-microbe interactions in...

10.1080/07352689.2022.2031728 article EN Critical Reviews in Plant Sciences 2021-11-02

Oat (Avena sativa L.), a hexaploid crop with unknown genome, has valuable nutritional, medicinal and pharmaceutical uses. However, no suitable RGs (reference genes) for qPCR (quantitative real-time PCR) been documented oat yet. Single-copy gene is often selected as RG, which challengeable or impactable in unexplored polyploids.In this study, eleven candidate RGs, including four duplicated genes, were from transcriptome. The stability the optimal combination of these assessed 18 samples by...

10.1186/s13007-020-00679-1 article EN cc-by Plant Methods 2020-10-15

Abstract In recent years, hydrocolloids have been used extensively as enhancers in dough products. However, studies on the effect of hydrophilic polymers wheat gluten (WG) within are scarce. present study, poly‐γ‐glutamic acid (γ‐PGA), a new and healthy food additive, was added to WG investigate its hydration, rheological properties, structures WG. Results showed that with addition γ‐PGA, water‐holding capacity (WHC) content bound water increased, whereas immobilized decreased. addition,...

10.1111/1750-3841.15400 article EN Journal of Food Science 2020-08-28

Hydroxysteroid dehydrogenase (HSDs) is an oil-body sterol protein (steroleosin) with NADP(H) binding domain that belongs to the short-chain dehydrogenase/reductase (SDR) superfamily. There are numerous studies on characterization of HSDs in plants. However, thus far, evolutionary differentiation and divergence analysis these genes remain be explored. The current study used integrated method elucidate sequential evolution 64 sequenced plant genomes. Analyses were conducted their origins,...

10.3389/fpls.2023.1159394 article EN cc-by Frontiers in Plant Science 2023-06-15

Abstract Adventitious root (AR) formation is critical for cutting survival and nutrient absorption re-establishment. This complex genetic trait involves the interplay of nitrogen, endogenous hormones, several key genes. In this study, we treated GL-3 apple ( Malus domestica ) in vitro shoots with nitrate ammonium to determine their impact on AR formation, hormonal content, gene expression patterns. Nitrate treatment significantly promotes adventitious rooting by increasing cell division,...

10.1007/s44281-023-00020-5 article EN cc-by Horticulture Advances 2023-12-29

Potassium nitrate (KNO3) promotes adventitious root (AR) formation in apple stem cuttings. However, evidence for the possible involvement of cytokinin (CK) KNO3-mediated AR apples is still lacking. In this study, we used GL-3 microshoots and cultured them different treatment combinations. T1 (KNO3 9.4 mmol L-1 + 6-benzyl adenine, 6-BA 2.22 μmol L-1) T3 (6-BA treatments completely inhibited formation. control, T2 L-1), T4 lovastatin, Lov 1.24 developed ARs. But fewer shorter ARs, indicating...

10.1016/j.jia.2024.07.045 article EN cc-by-nc-nd Journal of Integrative Agriculture 2024-08-01

Despite having growing evidence discussing the role of steroleosins in crop plants, their systemic analysis has not been worked extensively.Therefore, bioinformatics tools were employed to study Arabidopsis (Arabidopsis thaliana) steroleosin comparison with reported Brassica napus and pine steroleosins.Based on molecular weight, eight divided into two groups, L-steroleosin (alkalescence) H-steroleosin (acidity except At5g50770).Phylogeny suggested that H-steroleosins are primitive.Moreover,...

10.36899/japs.2020.1.0016 article EN The Journal of Animal and Plant Sciences 2020-01-01

Abstract Introduction: Rap1 and Rap2, both small GTPases of the Ras family, serve as crucial regulators in cell polarity, adhesion, migration, lumen formation via crosstalk with cytoskeletal proteins. GTPase activating protein (Rap1GAP), which negatively regulates Rap2 activity, has found to be downregulated multiple cancers, including oropharyngeal squamous carcinoma, melanoma, papillary follicular thyroid colorectal carcinoma but not yet been studied breast cancer. In order determine if...

10.1158/1538-7445.am2011-3840 article EN Cancer Research 2011-04-01

Abstract Background: Oat ( Avena sativa L.), a hexaploid crop with unknown genome, has valuable nutritional, medicinal and pharmaceutical uses. However, no suitable RGs (reference genes) for qPCR (quantitative real-time PCR) been documented oat yet. Single-copy gene is often selected as RG, which challengeable or impactable in unexplored polyploids. Results: In this study, eleven candidate RGs, including four duplicated genes, were from transcriptome. The stability the optimal combination of...

10.21203/rs.3.rs-20962/v2 preprint EN cc-by Research Square (Research Square) 2020-07-31

Abstract Background: Oat ( Avena sativa L.), a hexaploid crop with unknown genome, has valuable nutritional, medicinal and pharmaceutical uses. However, no suitable RGs (reference genes) for qPCR (quantitative real-time PCR) been documented oat yet. Single-copy gene is often selected as RG, which challengeable or impactable in unexplored polyploids. Results: In this study, eleven candidate RGs, including four duplicated genes, were from transcriptome. The stability the optimal combination of...

10.21203/rs.3.rs-20962/v3 preprint EN cc-by Research Square (Research Square) 2020-09-22

<h3>Background</h3> XL092 is a novel, oral inhibitor of multiple receptor tyrosine kinases including MET, VEGFR2, AXL, and MER, which are implicated in tumor growth, metastasis, angiogenesis, immune modulation. has half-life ~21h, convenient for daily dosing managing tolerability. Preclinical studies plus an checkpoint (ICI) showed antitumor activity models. STELLAR-002 will evaluate the safety clinical alone combination with nivolumab ± ipilimumab patients advanced solid tumors. Presented...

10.1136/jitc-2022-sitc2022.0742 article EN Regular and Young Investigator Award Abstracts 2022-11-01

CycloparaphenylenesIn their Communication on page 13529, Michal Juríc ˇek et al. describe a neutral open-shell carbon nanoring and show that its reactivity is result of steric electronic effects the cycloparaphenylene framework.

10.1002/anie.202182411 article EN Angewandte Chemie International Edition 2021-06-01
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