Bo Jia

ORCID: 0000-0003-2378-5499
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About
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Research Areas
  • Pharmacological Effects of Natural Compounds
  • Inflammatory Bowel Disease
  • Gut microbiota and health
  • Chronic Kidney Disease and Diabetes
  • Mycobacterium research and diagnosis
  • Helicobacter pylori-related gastroenterology studies
  • Traditional Chinese Medicine Studies
  • Phytochemistry and Biological Activities
  • Rheumatoid Arthritis Research and Therapies
  • NF-κB Signaling Pathways
  • Polyoxometalates: Synthesis and Applications
  • Medicinal Plant Pharmacodynamics Research
  • Trace Elements in Health
  • Andrographolide Research and Applications
  • Traditional Chinese Medicine Analysis
  • Systemic Lupus Erythematosus Research
  • Ionic liquids properties and applications
  • Cancer Research and Treatments
  • Acute Kidney Injury Research
  • Renal Diseases and Glomerulopathies
  • Virus-based gene therapy research
  • Phytochemistry and biological activity of medicinal plants
  • Cardiac Structural Anomalies and Repair
  • RNA modifications and cancer
  • Pneumonia and Respiratory Infections

Chengdu University of Traditional Chinese Medicine
2005-2024

Robert Bosch (Germany)
2023

Fudan University
2011

Renal fibrosis (RF) is the end stage of several chronic kidney diseases. Its series changes include excessive accumulation extracellular matrix, epithelial-mesenchymal transition (EMT) renal tubular cells, fibroblast activation, immune cell infiltration, and apoptosis. RF can eventually lead to dysfunction or even failure. A large body evidence suggests that natural products in traditional Chinese medicine (TCM) have great potential for treating RF. In this article, we first describe recent...

10.1016/j.biopha.2023.116039 article EN Biomedicine & Pharmacotherapy 2023-12-28

Early detection and timely intervention are important for improving contrast-induced nephropathy (CIN) prognosis. Whether urinary N-acetyl-β-glucosaminidase (NAG) is a useful marker early of CIN was investigated in 590 patients undergoing diagnostic coronary angiography (CA) and/or therapeutic percutaneous (PCI) acute syndromes or stable angina, who received low-osmolality nonionic contrast agent. Urinary NAG, osmolality serum creatinine were measured before 1, 2 6 days after agent exposure....

10.1177/147323001103900234 article EN Journal of International Medical Research 2011-04-01

BackgroundIt has recently been determined that N6-methyladenosine (m6A) RNA methylation regulators have prominent effects on several cancers. However, the potential role of m6A modification in lung squamous cell carcinoma (LUSC) remains unclear.MethodsWe evaluated pattern and studied biological function LUSC. Then, we constructed m6Ascore to predict prognosis LUSC analyzed relationship between tumor mutation burden, immune infiltration, immunotherapy.ResultIn unsupervised consensus cluster...

10.1016/j.heliyon.2024.e26851 article EN cc-by-nc-nd Heliyon 2024-02-28

Tanreqing injection, as a kind of traditional Chinese medicine injection widely used in clinic, has the effects clearing heat, reducing phlegm and detoxifying, avoids problems slow effect complicated decocting medicine. Severe pneumonia is critical disease respiratory system, with symptoms such dyspnea, shortness breath, high fever, coma. Clinical studies have found that combined Western good treatment severe pneumonia. In order to explore efficacy safety antibiotics pneumonia, we plan...

10.1097/md.0000000000022010 article EN cc-by-nc Medicine 2020-08-26

Rheumatoid arthritis has the characteristics of slow progression, long course, and repeated attacks. At present, western medicine commonly used in clinical practice not only reduces pain improves symptoms, but also more adverse reactions, affecting health, life patients. In ancient China, Huangqi Guizhi Wuwu decoction was by doctors to treat rheumatoid arthritis, with remarkable effect. recent years, many studies have shown that reliable effect treating there is no evidence evidence-based...

10.1097/md.0000000000022011 article EN cc-by-nc Medicine 2020-09-01

Renshen Baidu Powder (RBP) is a famous classic compound of traditional Chinese medicine (TCM) and commonly used for treating ulcerative colitis (UC). However, the pharmacological mechanism RBP in UC remains unclear. This study investigates possible treatment by network analysis rat validation.First, main chemical constituents were identified using ultrahigh-performance liquid chromatography quadrupole Orbitrap high-resolution mass spectrometry (UHPLC-Q-Orbitrap-HRMS). Then, we obtained...

10.1155/2022/5234025 article EN Evidence-based Complementary and Alternative Medicine 2022-07-30

Ulcerative colitis (UC) is a chronic inflammatory disease that involves the rectum, colon and ileum. Gancao Xiexin decoction (GCXXD) classic herbal formula in Shanghanlun. More more research evidence shows GCXXD has certain therapeutic effect on UC. Therefore, we designed this study protocol aim to evaluate efficacy safety of combine with mesalazine for UC.We will systematically search 6 databases, including PubMed, Cochrane Library, EMBASE, CNKI, VIP, Wang-fang database up July 2020 obtain...

10.1097/md.0000000000023038 article EN cc-by-nc Medicine 2020-11-18

Pancreatic cancer ranks seventh in terms of cancer‑related mortality men and women worldwide, where the most common subtype is pancreatic ductal adenocarcinoma (PDAC). To date, pathogenesis PDAC remains incompletely understood prognosis poor. In present study, expression interleukin‑28 receptor α subunit (IL‑28RA) tissues was detected using immunofluorescence staining western blotting. IL‑28RA recombinant plasmids control pCMV6‑entrymammalian plasmid, short hairpin (sh)IL‑28RA pRS scrambled...

10.3892/ijo.2021.5235 article EN International Journal of Oncology 2021-06-22

…were employed for selective cationic dimerization of a-methylstyrene (aMS) derivatives to synthesize exo-olefin compounds and subsequent sulfur-free RAFT polymerization aMS isobutylene (IB) produce polymers with controlled structures,respectively,a sreported by Masami Kamigaito et al. in their Research Article (e202307791). Nitrogen FixationAn ovel molybdenum complex bearing aP NP-type pincer ligand is reported Kazunari Yoshizawa, Yoshiaki Nishibayashi (e202306631).Thec omplex worked as an...

10.1002/ange.202384311 article EN Angewandte Chemie 2023-10-16
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