Istoni da Luz Sant’Ana

ORCID: 0000-0003-2407-6854
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About
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Research Areas
  • Cardiac Valve Diseases and Treatments
  • Statistical Methods in Clinical Trials
  • Disaster Response and Management
  • Cardiac, Anesthesia and Surgical Outcomes
  • Computational Drug Discovery Methods
  • Cardiac Imaging and Diagnostics
  • Health and Conflict Studies
  • Climate Change and Health Impacts
  • Infective Endocarditis Diagnosis and Management
  • Market Dynamics and Volatility
  • Acute Myocardial Infarction Research
  • Amyotrophic Lateral Sclerosis Research
  • Pharmacogenetics and Drug Metabolism
  • Hydrocarbon exploration and reservoir analysis
  • Global Energy and Sustainability Research

University of Puerto Rico, Medical Sciences Campus
2018-2023

University of Puerto Rico System
2020

Despite some previous examples of successful application to the field pharmacogenomics, utility machine learning (ML) techniques for warfarin dose predictions in Caribbean Hispanic patients has yet be fully evaluated. This study compares seven ML methods predict dosing Hispanics. is a secondary analysis genetic and non-genetic clinical data from 190 cardiovascular patients. Seven algorithms were applied data. Data was divided into 80 20% used as training test sets. trained with set obtain...

10.3389/fphar.2019.01550 article EN cc-by Frontiers in Pharmacology 2020-01-21

This study investigated the impact of cancer diagnosis status, individual feelings preparedness, and other covariates on objective emergency preparedness among women diagnosed with gynecological cancers before or after 2017 Hurricanes Irma Maria in Puerto Rico. included 240 who were interviewed by telephone from 9/2019–11/2020. Objective was assessed using a list six items. Subjective asking how prepared they felt (well, somewhat, not at all) to face an emergency. Crude multivariable...

10.1016/j.jcpo.2023.100415 article EN cc-by Journal of Cancer Policy 2023-02-23

Accurately charting the progress of oil production is a problem great current interest. Oil widely known to be cyclical: in any given system, after it reaches its peak, decline will begin. With this mind, Marion King Hubbert developed his peak theory 1956 based on bell-shaped curve that bears name. In present work, we consider stochasticmodel diffusion processes and associated with curve. The maximum likelihood estimation parameters for process also considered. Since complex system equations...

10.1002/asmb.2306 article EN Applied Stochastic Models in Business and Industry 2018-01-24

Describe the clinical and sociodemographic characteristics of ALS cases in unique multidisciplinary clinic Puerto Rico (PR).

10.1212/wnl.0000000000206508 article EN Neurology 2024-04-09
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