A5072579717- Geriatric Care and Nursing Homes
- Emergency and Acute Care Studies
- Nursing Roles and Practices
- Nursing education and management
- Workplace Health and Well-being
- Global Health Workforce Issues
- Healthcare Policy and Management
- Primary Care and Health Outcomes
- Cardiomyopathy and Myosin Studies
- Hospital Admissions and Outcomes
- Family and Patient Care in Intensive Care Units
- Health Systems, Economic Evaluations, Quality of Life
- Healthcare professionals’ stress and burnout
- Patient Satisfaction in Healthcare
- Sleep and Work-Related Fatigue
- Palliative Care and End-of-Life Issues
- Interprofessional Education and Collaboration
- Healthcare Quality and Management
- Frailty in Older Adults
- Patient Safety and Medication Errors
- Muscle Physiology and Disorders
- Global Health Care Issues
- Intensive Care Unit Cognitive Disorders
- Nursing Diagnosis and Documentation
- Health Sciences Research and Education
University of Southampton
2016-2025
King's College London
2005-2025
National Institute for Health Research
2016-2025
Portsmouth Hospitals NHS Trust
2018-2024
NIHR Applied Research Collaboration West
2023-2024
NIHR Clinical Research Network
2024
University Hospital Southampton NHS Foundation Trust
2023
Microtest (United Kingdom)
2023
University of Pennsylvania
2014-2022
Karolinska Institutet
2018-2021
<b>Objective</b> To determine whether hospitals with a good organisation of care (such as improved nurse staffing and work environments) can affect patient workforce stability in European countries. <b>Design</b> Cross sectional surveys patients nurses. <b>Setting</b> Nurses were surveyed general acute (488 12 countries; 617 the United States); 210 430 US hospitals. <b>Participants</b> 33 659 nurses 11 318 Europe; 27 509 more than 120 000 US. <b>Main outcome measures</b> Nurse outcomes...
To determine the association of hospital nursing skill mix with patient mortality, ratings their care and indicators quality care.Cross-sectional discharge data, characteristics nurse survey data were merged analysed using generalised estimating equations (GEE) logistic regression models.Adult acute hospitals in Belgium, England, Finland, Ireland, Spain Switzerland.Survey collected from 13 077 nurses 243 hospitals, 18 828 patients 182 same six countries. Discharge obtained for 275 519...
There is strong evidence to show that lower nurse staffing levels in hospitals are associated with worse patient outcomes. One hypothesised mechanism the omission of necessary nursing care caused by time pressure-'missed care'.To examine nature and prevalence left undone nurses English National Health Service assess whether number missed episodes ratings quality safety environment.Cross-sectional survey 2917 registered working 401 general medical/surgical wards 46 acute England.Most (86%)...
Glutathione peroxidases have been thought to function in cellular antioxidant defense. However, some recent studies on <i>Gpx1</i> knockout (−/−) mice failed show a role for Gpx1 under conditions of oxidative stress such as hyperbaric oxygen and the exposure eye lenses high levels H<sub>2</sub>O<sub>2</sub>. These findings have, unexpectedly, raised issue Gpx1, especially stress. Here we demonstrate protection against by showing that are highly sensitive oxidant paraquat. Lethality was...
Variation in post-operative mortality rates has been associated with differences registered nurse staffing levels. When levels are lower there is also a higher incidence of necessary but missed nursing care. Missed care may be significant predictor patient following surgery. Examine if mediates the observed association between and mortality. Data from RN4CAST study (2009–2011) combined routinely collected data on 422,730 surgical patients 300 general acute hospitals 9 countries, survey...
Abstract Background Current human resources planning models in nursing are unreliable and ineffective as they consider volumes, but ignore effects on quality patient care. The project RN4CAST aims innovative forecasting methods by addressing not only of staff well Methods/Design A multi-country, multilevel cross-sectional design is used to obtain important unmeasured factors including how features hospital work environments impact nurse recruitment, retention outcomes. In each the 12...
12 h shifts are becoming increasingly common for hospital nurses but there is concern that long adversely affect nurses' well-being, job satisfaction and intention to leave their job. The aim of this study examine the association between working burnout, dissatisfaction, dissatisfaction with work schedule flexibility current among nurses.Cross-sectional survey 31,627 registered in 2170 general medical/surgical units within 488 hospitals across European countries.Nurses ≥12 were more likely...
World-wide, shortages of primary care physicians and an increased demand for services have provided the impetus delivering team-based care. The diversity workforce is increasing to include a wider range health professionals such as nurse practitioners, registered nurses other clinical staff members. Although this development observed internationally, skill mix in team speed progress deliver differs across countries. This work aims provide overview education, tasks remuneration members six...
To determine the association between daily levels of registered nurse (RN) and nursing assistant staffing hospital mortality.This is a retrospective longitudinal observational study using routinely collected data. We used multilevel/hierarchical mixed-effects regression models to explore patient outcomes variation in RN staffing, measured as hours per day relative ward mean. Analyses were controlled for risk.138 133 adult patients spending >1 days on general wards 1 April 2012 31 March...
To inform healthcare workforce policy decisions by showing how patient perceptions of hospital care are associated with confidence in nurses and doctors, nurse staffing levels work environments.
Background: Despite concerns as to whether nurses can perform reliably and effectively when working longer shifts, a pattern of two 12- 13-hour shifts per day is becoming common in many hospitals reduce shift handovers, staffing overlap, hence costs. Objectives: To describe patterns European investigate length beyond contracted hours (overtime) associated with nurse-reported care quality, safety, left undone. Methods: Cross-sectional survey 31,627 registered general medical/surgical units...
The importance of nurse staffing levels in acute hospital wards is widely recognised but evidence for tools to determine requirements although extensive, has been reported be weak. Building on a review reviews undertaken 2014, we set out give an overview the major approaches assessing and identify recent order address unanswered questions including accuracy effectiveness tools. We undertook systematic scoping review. Searches Medline, Cochrane Library CINAHL were used primary research, which...
Abstract The methodological issues surrounding the use of a privileged access interviewer team to generate network sample drug users are examined. Traditionally samples have tended be used by qualitative researchers. Privileged interviewing provides mechanism for application structured instrument sampling model. In doing so some problematic in this area methodology overcome, reduced or standardized. method is appraised terms meeting requirements Drug Transitions study. practical experiences...
Dilated cardiomyopathy and hypertrophic (HCM) can be caused by mutations in thin filament regulatory proteins of the contractile apparatus. In vitro functional assays show that, general, presence dilated decreases Ca 2+ sensitivity contractility, whereas HCM increase it. To assess whether this phenomenon was a direct result altered affinity or troponin–tropomyosin switching, we assessed binding site cardiac troponin C wild-type mutant complex filaments using fluorescent probe...