A5074079505- Tuberculosis Research and Epidemiology
- HIV/AIDS Research and Interventions
- HIV, Drug Use, Sexual Risk
- Pneumonia and Respiratory Infections
- HIV/AIDS Impact and Responses
- Global Maternal and Child Health
- Diagnosis and treatment of tuberculosis
- Pneumocystis jirovecii pneumonia detection and treatment
- Mycobacterium research and diagnosis
- Diabetic Foot Ulcer Assessment and Management
- HIV Research and Treatment
- Adolescent Sexual and Reproductive Health
- Wound Healing and Treatments
- Viral Infections and Outbreaks Research
- Malaria Research and Control
- Vaccine Coverage and Hesitancy
- Pressure Ulcer Prevention and Management
- Zoonotic diseases and public health
- SARS-CoV-2 and COVID-19 Research
- Antibiotic Use and Resistance
- Data-Driven Disease Surveillance
- Health Policy Implementation Science
- Mosquito-borne diseases and control
- Occupational Health and Safety Research
- Bacillus and Francisella bacterial research
University of Zimbabwe
2004-2025
Parirenyatwa Hospital
2021
South African Medical Research Council
2019-2020
Stellenbosch University
2019-2020
Community Medical Center
2018-2020
University of Bahrain
2015
Botswana Vaccine Institute (Botswana)
2013
Abstract Background Previous studies have shown gender differences in tuberculosis (TB) incidence; however, disparity has not been well documented across granular categorizations of anatomic sites affected by TB and the presence human immunodeficiency virus (HIV) coinfection, largely due to small sample size for less common clinical presentations lack detailed data. Methods The study population included cases aged ≥15 years (n = 41, 266) diagnosed Harare, Zimbabwe. This cross-sectional...
local contexts in each of the respective countries.
To determine the incidence and major drivers of catastrophic costs among TB-affected households in Zimbabwe.We conducted a nationally representative health facility-based survey with random cluster sampling consecutively enrolled drug-susceptible (DS-TB) drug-resistant TB (DR-TB) patients. Costs incurred income lost due to illness were captured using an interviewer-administered standardised questionnaire. We used multivariable logistic regression risk factors for experiencing costs.A total...
Introduction Accurate mapping of spatial heterogeneity in tuberculosis (TB) cases is critical for achieving high impact control as well guide resource allocation most developing countries. The main aim this study was to explore the patterns TB occurrence at district level Zimbabwe from 2015 2018 using GIS and statistics a preamble identifying areas with elevated risk prioritisation intervention measures. Methods In Getis-Ord G i * together SaTscan were used characterise hotspots clusters...
Abstract Background Although effective treatment for malaria is now available, approximately half of the global population remain at risk disease particularly in developing countries. To design control strategies there need to understand pattern heterogeneity an area. Therefore, main objective this study was explore spatial and spatio-temporal cases Zimbabwe based on data aggregated district level from 2011 2016. Methods Geographical information system (GIS) scan statistic were applied...
Abstract Background Diabetic foot disease (DF) is a common diabetes-related complication; however, the prevalence and associated risk factors for DF are not well characterised among people living with diabetes (PLWD) in Zimbabwe. This may suggest unavailability of adequate strategies to diagnose treat country. study aimed determine PLWD Harare, Methods was cross-sectional study, employing quantitative approach. In total, 352 were recruited from 16 primary care clinics Harare....
Introduction Zimbabwe exclusively implemented targeted HIV testing until 2022 when Status-neutral was embraced. Whilst aims to expand access and uptake of among high-risk individuals, status-neutral emphasizes post-test linkage prevention treatment services. To address how the two concepts relate in practice, we explored correlate, developing a double-edged strategy for effective case identification treatment. Methods We conducted cross-sectional study on 36 multi-stage sampled sites across...
Rapid urbanisation in low- and middle-income countries (LMICs) has intensified the double burden of malnutrition, where undernutrition overnutrition coexist same populationAim: This study aimed to examine point prevalence rate risk factors malnutrition among adults urban Zimbabwe. The was conducted Zimbabwe's two metropolitan provinces (Harare Bulawayo). A cross-sectional 348 explored associations between dietary intake, socio-demographics anthropometrics using means, frequencies, logistic...
Introduction: The Kunda-Nqob’I TB program introduced the full package of Palliative Care to improve quality life and treatment results for patients with tuberculosis (TB). components care include adherence, physical, psychosocial support. physical support provides pain relief, while involves counselling cope stress associated TB. Treatment adherence included directly observed by a community-based volunteer. Among five districts in Midlands province implementing Care, Chirumhanzu had highest...
Although approximately 0.5 million cases of multidrug-resistant tuberculosis (MDR-TB) occur globally each year, surveillance data are limited. Botswana is one the few high TB burden countries to have carried out multiple anti-tuberculosis drug resistance surveys (in 1995-1996, 1999 and 2002).In 2007-2008, we conducted fourth national survey in assess resistance, including trends over time. In previous survey, 0.8% (95%CI 0.4-1.5) new patients 10.4% 5.6-17.3) previously treated had...
The contribution of high tuberculosis (TB) transmission pockets in propagating area-wide has not been adequately described Zimbabwe. This study aimed to describe the presence hotspot TB cases Harare city from 2011 2012 using geospatial techniques.
ObjectiveTo determine the prevalence of resistance to rifampicin alone; and isoniazid, second-line anti-TB drugs among sputum smear-positive tuberculosis patients in Zimbabwe.DesignA health facility-based cross-sectional survey.ResultsIn total, 1114 (87.6%) new 158 (12.4%) retreatment TB were enrolled. MTB was confirmed by Xpert MTB/RIF 1184 (93%) samples. There 64 samples with MTB/RIF-determined resistance. However, two susceptible on phenotypic drug susceptibility testing. The RR-TB [4.0%...
Malaria burden has considerably declined in the last 15 years mainly due to large-scale vector control. The continued decline can be sustained through malaria risk stratification. stratification is classification of geographical areas according risk. In this study, ecological niche modelling using maximum entropy algorithm was applied predict habitat suitability terms bioclimatic and topographic variables. output map integrated with prevalence data a GIS stratify Zimbabwe into different...
To determine the association between HIV infection and progression of Plasmodium falciparum malaria illness in Hurungwe district, Zimbabwe.Prospective cohort.Hurungwe Rural Hospital Mashonaland West Province, Zimbabwe.Blood slide positive P. patients.Development severe complicated malaria.A total 659 clinical cases were investigated 237 (36.0%) confirmed entered study. The patients 82 (34.6%) or 12.4% cases. case fatality rate was 5.9% (14 deaths) 11 these deaths positive. commonly reported...
Failure to thrive (FTT) is a sign of tuberculosis (TB) and human immunodeficiency virus (HIV) infection. We assessed TB HIV prevalence in children with FTT at one clinic Botswana.In July 2010, we screened all attending 'Well Child' for FTT. Children were referred paediatrician who: (i) causes FTT, (ii) evaluated (iii) reviewed the patient chart evaluations HIV.Of 919 screened, 176 (19%) had One hundred eighteen (67%) saw paediatrician, these, 95 (81%) completed evaluation. was newly...
To determine behaviour factors for contracting human cutaneous anthrax among residents of Musadzi area.We conducted a matched case-control study age, sex, and village.A rural community in area Gokwe North district.We interviewed 35 cases controls. A case was defined as any resident/visitor Musadzi, diagnosed with between 9 September 10 November 2004. control resident who had not been no lesions suggestive ofanthrax on day the interview.Behaviour associated anthrax.In 2004, cattle were...
Country-specific interventions targeting high-risk groups are necessary for a global reduction in Tuberculosis (TB)/HIV burden. We analyzed the data of 13,802 TB cases diagnosed Harare, Zimbabwe, during 2013-2017. Pearson's chi-square tests and multivariate logistic regression models were used to identify patient characteristics significantly associated with TB/HIV coinfection. Of analyzed, 9,725 (70.5%) HIV positive. A higher odds having coinfection diagnosis was found among females,...
To examine the prevalence, patterns and reasons for disclosure of HIV status among people living with HIV/AIDS.Adescriptive cross sectional survey.FamilyAIDS Support Organisation (FASO), Mutare, Zimbabwe.A random selection members FASO attending clinic or meetings.Disclosure seropositivity to sexual partner, one more family members, health care workers wider public.There was 79%, 72% 70% family, partners respectively. While public 23%, wanted disclose but did not get an opportunity. Main...
In Botswana, where one quarter of the adult population is infected with human immunodeficiency virus and annual tuberculosis (TB) incidence among highest globally, intensified TB case finding needed in health care facilities to detect treat cases early prevent transmission. During August-December 2009, screening was implemented adults at patient intake five clinics Francistown. Among 11 779 screenings intake, 926 were positive. Nineteen patients diagnosed TB. Routine operationally feasible,...
A baseline assessment was conducted to describe the current landscape and opportunities for operationalising One Health (OH) in Zimbabwe. desktop review, focus group discussion key informant interviews were used collect data. predetermined analysis reporting format including sections on research innovation, governance, education implementation Zimbabwe used. Key informants discussants selected from senior experts government, academia, parastatals private organisations. The study revealed...
(2020). Perspectives of healthcare workers on factors influencing diabetes management and diabetic foot problems in Zimbabwe. Journal Endocrinology, Metabolism Diabetes South Africa: Vol. 25, No. 3, pp. 57-62.
Tuberculosis (TB) has remained one of the major public health problems in Zimbabwe with an estimated incidence rate 552 per 100,000 persons 2013. The aim this study was to describe trends acid-fast bacilli (AFB) sputum-smear positive (SSP) TB overall and within subpopulations for period during 2008–2011 Zimbabwe. Results will contribute towards evaluation implementation targeted control interventions. A cross-sectional design used analyze 40, 110 SSP patient records routinely collected...