A5061420706- Pharmaceutical studies and practices
- Mobile Health and mHealth Applications
- Pharmaceutical Practices and Patient Outcomes
- Health Systems, Economic Evaluations, Quality of Life
- Allergic Rhinitis and Sensitization
- COVID-19 Clinical Research Studies
- Poisoning and overdose treatments
- Patient Satisfaction in Healthcare
- Technology Adoption and User Behaviour
- Health Literacy and Information Accessibility
- Electronic Health Records Systems
- Drug-Induced Adverse Reactions
- Pharmacovigilance and Adverse Drug Reactions
- Pharmaceutical Economics and Policy
- Pharmacological Receptor Mechanisms and Effects
- Dermatology and Skin Diseases
- Asthma and respiratory diseases
- Antimicrobial Resistance in Staphylococcus
- Long-Term Effects of COVID-19
- Cardiac Arrest and Resuscitation
- Food Allergy and Anaphylaxis Research
- Renal function and acid-base balance
- Respiratory and Cough-Related Research
- Pharmaceutical industry and healthcare
- Antibiotics Pharmacokinetics and Efficacy
King Saud bin Abdulaziz University for Health Sciences
2018-2025
National Guard Health Affairs
2018-2025
King Abdullah International Medical Research Center
2020-2025
King Abdulaziz Medical City
2018-2025
King Fahad Hospital Jeddah
2023
Cardiff University
2020
Ibuprofen disappeared from the pharmacy shelves during 2019 coronavirus (COVID-19) pandemic. However, a while later, information circulated that ibuprofen should be avoided as it could worsen COVID-19 symptoms. The aim of our study was to assess association acute and chronic use nonsteroidal anti-inflammatory drugs (NSAIDs) with worse outcomes. We did prospective cohort between April 12 June 1, 2020. Adults consecutively diagnosed were included. Information on NSAID collected through...
Abstract Background Acute methanol intoxication, whether unintentional or deliberate, necessitates prompt intervention to prevent severe morbidity and mortality. Homemade alcoholic beverages are a frequent source of such poisoning. This retrospective analysis examined two outbreaks intoxication in Saudi Arabia. It investigated the clinical presentation, implemented management strategies, any lasting complications (sequelae) associated with these cases. The aim was assess potential impact...
Personal health records (PHRs) are eHealth tools designed to support patient engagement, empowerment, and patient- person-centered care. Endorsement of a PHR by care providers (HCPs) facilitates acceptance. As organizations in the Kingdom Saudi Arabia begin adopt PHRs, understanding perspectives HCPs is important because it can influence adoption. However, no studies evaluated HCPs' acceptance PHRs Arabia.The aim this study was identify predictors using behavioral intention recommend as...
Objectives: Several cases of unusual thrombotic events with thrombocytopenia were reported in several countries, association AstraZeneca's COVID-19 vaccine. The European medicines agency conducted a detailed review and concluded that there was no evidence to suggest an the use vaccine AstraZeneca.Methods: King Abdulaziz Medical City is 1500 bed tertiary care hospital Riyadh, Saudi Arabia; this study describes spontaneously adverse effects received through hospital's internal electronic...
As health care organizations strive to improve access, quality, and costs, they have implemented patient-facing eHealth technologies such as personal records better engage patients in the management of their health. In Kingdom Saudi Arabia, is also growing accordance with Vision 2030 its National Transformation Program framework, creating a roadmap for increased quality efficiency system supporting goal patient-centered care.
Biosimilars have the potential to offer cost savings with comparable efficacy and safety innovator products and, thus, increase access treatment for more patients. However, there were significant challenges in acceptance of oncology biosimilars our organization beginning which we addressed by implementing practical strategies described paper. While much published literature places an emphasis on pharmacoeconomic impact biosimilars, this paper is a novel addition because it provides...
Managed entry agreements (MEAs) between manufacturers and healthcare payers allow health systems to maximize patients' access treatments while maintaining financial sustainability. However, work efficiently, MEAs need be integrated into a country's formal pricing, reimbursement, market processes. This study proposes country-specific MEA framework for pharmaceutical products sheds light on the key enablers of optimal implementation in Saudi Arabia. mixed-methods was conducted through...
Background With the rise in use of information and communication technologies health care, patients have been encouraged to eHealth tools such as personal records (PHRs) for better well-being services. PHRs support patient-centered care patient engagement. To achievement Kingdom Saudi Arabia’s Vision 2030 ambitions, National Transformation program provides a framework meeting 3-fold aim care—increased access, reduced cost, improved quality care—and provide patient- person-centered care....
Limitations of clinical trials in determining all safety concerns related to a drug are well recognized. Monitoring spontaneous adverse reaction (ADR) reports remains an easy and relatively inexpensive method for overseeing that safe effective option patients.To characterize describe ADR at one the largest healthcare institutions region share measures implemented by team.We conducted retrospective analysis ADRs submitted providers tertiary system Saudi Arabia between January 2016 December...
ABSTRACT Introduction Lomitapide is approved for lowering low-density lipoprotein cholesterol (LDL-C) in homozygous familial hypercholesterolemia, which a rare genetic disorder. The evidence regarding its safety and efficacy from small clinical trial requires further validation effectiveness the real world. This study aimed to use institutional data on of lomitapide assist formulating perspective adding it formulary. Methods was retrospective review patients who were actively prescribed at...
Linezolid and vancomycin have an important place among therapeutic antimicrobial options for multidrug-resistant gram-positive infections. Thrombocytopenia is adverse effect reported with both can lead to treatment interruption. Our objective was compare the incidence of thrombocytopenia in patients receiving linezolid or identify risk factors associated thrombocytopenia.This a retrospective observational cohort study that involved who received (intravenously orally) (intravenously) at...
Fixed-dose combinations (FDCs) are marketed with the promise of optimum patient adherence, improvement in disease management and lower cost. P&T decision makers commonly overlook some factors that may render a FDC poor choice. A working group utilizing three-step modified Delphi method to develop consensus checklist factor consider when evaluating product for formulary inclusion. The developed comprehensive list be considered addition included point related to: evidence improved outcomes,...
Background. Vancomycin and piperacillin-tazobactam (PTZ) are commonly used as empirical therapy for patients with health care associated infections. has been recognized a nephrotoxic agent in few cases the literature PTZ interstitial nephritis nevertheless; combination of these agents routinely many years. However, there have some observational studies that showed high rates acute kidney injury (AKI) receiving vancomycin concomitant treatment compared to alone. The incidence AKI adult was...
Abstract Administering medications to patients with documented drug hypersensitivity reactions (DHR) poses a significant risk for adverse events, ranging from mild life-threatening incidents. Electronic healthcare systems have revolutionized the modern clinical decision-making process, built in warnings. However, as these alerts become routine part of provider’s workflow, alert fatigue becomes challenge. This study was conducted within Ministry National Guard Health Affairs (MNGHA),...
Personal health records (PHRs) can facilitate patient-centered communication through the secure messaging feature. As care organizations in Kingdom of Saudi Arabia implement PHRs and begin to feature, studies are needed evaluate providers' acceptance.
Aims: Atopic dermatitis (AD) is a chronic skin disease that creates significant burden to patients and society. There scarcity in local data about the of AD Kingdom Saudi Arabia (KSA). We aimed fill this gap quantify humanistic economic among adults adolescents KSA.Materials methods: A literature search expert interviews were conducted assess burden. Prevalence values estimated through literature. International health-related quality life lost owing was adjusted age prevalence KSA. Direct...
Background: In a series of cases that came to be recognized as national methanol outbreak, an incident delay in allocation and treatment with the antidote fomepizole is described aim sharing learning experience. Method: A team 16 members was formed conduct Root Cause Analysis (RCA), which included multiple individual interviews stakeholders inspection visits area. Results: causes: The restocking process unclear inconsistent specifically lacked policy for antidotes, inappropriate labeling...
Antimicrobial-associated anaphylaxis occurs at different rates and can lead to worsening infection-related outcomes, we sought describe the incidence complications of such episodes a tertiary care hospital.A retrospective cohort study was conducted between January 2016 December 2019. Cases antimicrobial-associated were identifiedusing hospital's electronic healthcare records. Outcomes included: mortality related anaphylaxis, mortality, hospitalization impact on antimicrobial prescribing.The...
The COVID-19 pandemic presented many psychological stressors which affected healthcare worker wellbeing. aim of this study was to understand the factors that affect wellbeing professionals in Kingdom Saudi Arabia using Job-Demand and Resource (JD-R) Model. proposal model consisted demand (Work load—job demand, loneliness—personal demand), support (organizational support—job resource, resilience—personal resource), mediators (burnout work engagement), outcome (wellbeing) A cross-sectional,...