- Vestibular and auditory disorders
- Head and Neck Surgical Oncology
- Head and Neck Cancer Studies
- Ophthalmology and Eye Disorders
- Bone Tumor Diagnosis and Treatments
- Glaucoma and retinal disorders
- Radiomics and Machine Learning in Medical Imaging
- Hearing, Cochlea, Tinnitus, Genetics
- Cerebral Venous Sinus Thrombosis
- Salivary Gland Tumors Diagnosis and Treatment
- Ear Surgery and Otitis Media
- Ocular Diseases and Behçet’s Syndrome
- Oral and Maxillofacial Pathology
- Multiple Sclerosis Research Studies
- Sarcoma Diagnosis and Treatment
- Advanced X-ray and CT Imaging
- Lung Cancer Research Studies
- Otolaryngology and Infectious Diseases
- Cancer and Skin Lesions
- Neuroendocrine Tumor Research Advances
- Soft tissue tumor case studies
- Vascular Tumors and Angiosarcomas
- Lymphoma Diagnosis and Treatment
- Ear and Head Tumors
- Craniofacial Disorders and Treatments
Eye & ENT Hospital of Fudan University
2019-2025
Fudan University
2024-2025
Yueyang Changling Equipment Research Institute (China)
2022
Creative Commons
2020
Shanghai Jiao Tong University
2014
Background To compare three different curve-fitting methods for intravoxel incoherent motion (IVIM) analysis in breast cancer. Methods Diffusion-weighted imaging was acquired 30 patients with cancer using seven b-values (0–800 s/mm2). Three were used biexponential IVIM analysis: a. Direct estimation of D (diffusion coefficient), D* (pseudodiffusion coefficient) and f (perfusion fraction) (Method 1), b. Estimation first then 2), c. 3). Goodness-of-fit, parameter precision (coefficient...
Nasopharyngeal carcinoma (NPC) patients often undergo radiotherapy and chemotherapy, which can lead to postoperative complications such as limited mouth opening joint stiffness, particularly in recurrent cases that require re-surgery. These affect airway function, making accurate risk assessment essential for managing patient care. Accurate segmentation of airway-related structures CT scans is crucial assessing these risks. This study introduces TopoWMamba (Topology-aware Wavelet Mamba), a...
To develop MRI-based deep learning (DL) models for distinguishing sinonasal squamous cell carcinoma (SCC), adenoid cystic (ACC) and olfactory neuroblastoma (ONB) to evaluate whether the DL could improve diagnostic performance of Senior radiologist (SR) Junior (JR). This retrospective analysis consisted 465 patients (229 SCCs, 128 ACCs 108 ONBs). The training validation cohorts included 325 47 independent external testing cohort 93 patients. MRI images T2-weighted image (T2WI),...
This study aimed to assess the diagnostic accuracy of combining MRI hand-crafted (HC) radiomics features with deep transfer learning (DTL) in identifying sinonasal squamous cell carcinoma (SCC), adenoid cystic (ACC), and non-Hodgkin's lymphoma (NHL) using various machine (ML) models. A retrospective analysis 132 patients (50 SCC, 42 NHL, 40 ACC) was conducted. The dataset split 80/20 into training testing cohorts. HC DTL were extracted from T2-weighted, ADC, contrast-enhanced T1-weighted...
Purpose Based on comparison of different machine learning (ML) models, we developed the model that integrates traditional hand-crafted (HC) features and ResNet50 network-based deep transfer (DTL) from multiparametric MRI to predict Ki-67 status in sinonasal squamous cell carcinoma (SNSCC). Methods Two hundred thirty-one SNSCC patients were retrospectively reviewed [training cohort (n = 185), test 46)]. Pathological grade, clinical, characteristics analyzed choose independent predictor. HC...
Abstract Background Mandibulofacial dysostosis with microcephaly (MFDM, OMIM# 610536) is a rare monogenic disease that caused by mutation in the elongation factor Tu GTP binding domain containing 2 gene ( EFTUD2, OMIM* 603892). It characterized mandibulofacial dysplasia, microcephaly, malformed ears, cleft palate, growth and intellectual disability. MFDM can be easily misdiagnosed due to its phenotypic overlap other craniofacial syndromes. The clinical presentation of highly variable among...
To develop and validate a nomogram model combining radiomic features clinical characteristics to preoperatively predict the risk of early relapse (ER) in advanced sinonasal squamous cell carcinomas (SNSCCs).A total 152 SNSCC patients (clinical stage III-IV) who underwent diffusion-weighted imaging (DWI) were included this study. The training cohort 106 assessed at headquarters our hospital using MR scanner 1. testing 46 branch 2. Least absolute shrinkage selection operator (LASSO) regression...
Purpose The purpose of this study was to explore the characteristic computed tomography (CT) and magnetic resonance (MR) features small cell neuroendocrine carcinoma (SNEC) paranasal sinuses. Materials Methods Computed (n = 8) MR 14) images clinical findings from 14 patients with SNEC sinuses were retrospectively reviewed. Results Eight lesions located in ethmoidal sinus, 4 maxillary 2 sphenoid sinus. Small sinus showed bilateral asymmetry patterns. On CT images, bony changes visible all 8...
The aim of this study was to construct and validate a noninvasive radiomics method based on magnetic resonance imaging differentiate sinonasal extranodal natural killer/T-cell lymphoma from diffuse large B-cell lymphoma.We collected scans, including contrast-enhanced T1-weighted T2-weighted imaging, 133 patients with non-Hodgkin (103 30 lymphoma) randomly split them into training testing cohorts at ratio 7:3. Clinical characteristics image performance were analyzed build logistic regression...
Intravenous gadoteridol injection can be applied to visualize endolymphatic hydrops (EH).To explore whether 3.5-h time interval was feasible for clinical practice.We collected 70 unilateral Meniere's disease (MD) patients who were divided into two groups randomly (group A: interval; group B: 4-h interval). Among the groups, signal intensity (SI) in perilymphatic area of basal turn cochlea, results visual evaluations vestibule, cochlea and semicircular canal detection EH compared.Regarding...
Three-dimensional inversion-recovery sequence with real reconstruction (3D-real IR) magnetic resonance imaging (MRI) can detect endolymphatic hydrops of the inner ear. We aimed to explore a appropriate dose for intravenous gadolinium injection.Observational prospective study.Tertiary referral centre.We collected 90 unilateral definite Meniere's disease patients.All enrolled patients were divided into three groups randomly (patients in group A, B and C received injection 1/1.5/2 times doses...
Objective: To investigate the characteristics of endolymphatic hydrops (EH) in Menire's disease (MD) patient on a vertigo attack. Study Design: Prospective study. Setting: Tertiary referral center. Patients: Thirty-six MD patients underwent enhanced magnetic resonance imaging (MRI) examinations inner ear attack were enrolled. Main Outcome Measures: All met diagnostic criteria for and intravenous gadolinium injection 4 hours before MRI examinations. The performed Results: Various degrees...
Purpose The aim of the study was to develop and validate a nomogram model combining radiomic features clinical characteristics preoperatively differentiate between low- high-grade sinonasal squamous cell carcinomas. Material Methods A total 174 patients who underwent diffusion-weighted imaging were included in this study. allocated training testing cohorts randomly at ratio 6:4. least absolute shrinkage selection operator regression applied for feature signature (radscore) construction....
To investigate the correlation between clinical features and endolymphatic hydrops (EH) in children with sudden sensorineural hearing loss (SSNHL).We collected 30 SSNHL aged ≤17 years old, all of whom underwent intravenous gadolinium injection. After 4 hours, inner ear 3-dimensional inversion recovery sequence real reconstruction (3D-real IR) magnetic resonance imaging was performed. Combined their medical history such as gender, age, disease course, loss, so on, results were...
To analyze and summarize the clinical features image characteristics of Meniere's Disease (MD) patients with Endolymphatic Hydrops (EH) confirmed by enhanced Magnetic Resonance Imaging (MRI). 252 MD EH MRI were enrolled. All met diagnostic criteria for underwent intravenous gadolinium injection. After 4 h, MR examinations performed. The Nakashima grading standard was used to classify evaluate its correlation features. Different degrees shown in all patients, 157 (62.3%) showed significant...
Intravenous gadolinium injection (IV-method) can be used to visualize endolymphatic hydrops.This study was designed use a three-dimensional inversion-recovery sequence with real reconstruction (3 D-real IR) 4 h after the IV-method, images of perilymph space were scored for hydrops in cases suspected Meniere's disease (MD) children investigate its diagnostic value MD children.We collected 28 aged ≤17 years old, all whom underwent IV-method. After h, inner ear 3 IR magnetic resonance imaging...
The aim of the study was to explore value T2-sampling perfection with application-optimized contrasts by using different flip angle evolutions (T2-SPACE) in identifying space-occupying lesions inner ear.We collected T2-SPACE and 3-dimensional inversion-recovery sequence real reconstruction (3D-real IR) images 220 patients ear symptoms, including 15 lesions. With hidden, a senior junior radiologist made diagnosis for all only 3D-real IR images. After 4 weeks were shuffled, available 2...