A5090896517- Gold and Silver Nanoparticles Synthesis and Applications
- Innovative Microfluidic and Catalytic Techniques Innovation
- Magnetic properties of thin films
- Nanoplatforms for cancer theranostics
- Nanoparticle-Based Drug Delivery
- Plasmonic and Surface Plasmon Research
- ZnO doping and properties
- Anodic Oxide Films and Nanostructures
- Microfluidic and Capillary Electrophoresis Applications
- Quantum Dots Synthesis And Properties
- Copper-based nanomaterials and applications
- Catalytic Processes in Materials Science
- Electrocatalysts for Energy Conversion
- Metallic Glasses and Amorphous Alloys
- Magneto-Optical Properties and Applications
- Advanced biosensing and bioanalysis techniques
- Photonic and Optical Devices
- Semiconductor materials and devices
- Nanowire Synthesis and Applications
- Fuel Cells and Related Materials
- Soil erosion and sediment transport
- Nanofabrication and Lithography Techniques
- Nanoporous metals and alloys
- Adsorption and biosorption for pollutant removal
- Characterization and Applications of Magnetic Nanoparticles
Sichuan University
2023-2025
University of Science and Technology Beijing
2016-2025
Zhengzhou University of Science and Technology
2019-2025
Nanjing Foreign Language School
2024
Hohai University
2024
Harvard University
2019-2023
Beijing University of Chemical Technology
2005-2023
Henan Tianguan Group (China)
2023
Beijing Information Science & Technology University
2023
Haier Group (China)
2023
Co nanoparticles with three different crystal structures were synthesized in a microfluidic reactor through manipulation of reaction times, flow rates, and quenching procedures. Cobalt face-centered cubic (β) phase obtained from high rate the reactants followed by situ reaction. hcp ε-cobalt at low delayed quenching, respectively. The characterized using K-edge X-ray absorption near edge structure (XANES) spectroscopy, diffraction (XRD), selected area electron (SAED). In XANES measurements...
Abstract Hepatocellular carcinoma (HCC) is the third leading cause of cancer‐related death worldwide. The prognosis HCC remains very poor; thus, an effective treatment urgent. Herein, a type nanomedicine developed by conjugating Fe@Fe 3 O 4 nanoparticles with ginsenoside Rg3 (NpRg3), which achieves excellent coupling effect. In dimethylnitrosamine‐induced model, NpRg3 application significantly prolongs survival mice. Further research indicates that inhibits development and eliminates...
The application of flexible electronics in the field communication has made transition from rigid physical form to form. Flexible electrode technology is key wide electronics. However, electrodes will break when large deformation occurs, failing It restricts further development electronic technology. stretchable are a hot research topic solve problem that cannot withstand deformation. materials have excellent electrical conductivity, while retaining mechanical properties case This paper...
Intelligent responsive drug delivery system opens up new avenues for realizing safer and more effective combination immunotherapy. Herein, a kind of tumor cascade-targeted liposome (NLG919@Lip-pep1) is developed by conjugating polypeptide inhibitor PD-1 signal pathway (AUNP-12), which also targeted peptide that conjugated with carrier through matrix metalloproteinase-2 (MMP-2) cleavable (GPLGVRGD). This prepared mature preparation process, indoleamine-2,3-dioxygenase (IDO) NLG919 was...
Abstract The complex tumor immune pathology requires a precise spatial‐control release of the combination drugs, but most multi‐drug loaded nanoparticles all drugs simultaneously in microenvironment (TME), making them difficult to reach exact action site. To address spatial specific carrier‐free self‐assembled multi‐responsive nanodrug delivery system is designed, which p ‐phthalaldehyde ( ‐APA) and dithiodipropionic acid are used connect metformin (MET) 7‐ethyl‐10‐hydroxycamptothecin (SN38)...
Carrier-free nanomedicines exhibited significant potential in elevating drug efficacy and safety for tumor management, yet their self assembly typically relied on chemical modifications of drugs or the incorporation surfactants, thereby compromising drug’s inherent pharmacological activity. To address this challenge, we proposed a triethylamine (TEA)-mediated protonation–deprotonation strategy that enabled adjustable-proportion dual without modification, achieving nearly 100% loading...
Nitrogen and phosphorus-codoped graphene dots supported on nitrogen-doped three-dimensional (N, P-GDs/N-3DG) have been synthesized by a facile freeze-annealing process. On the surface of 3D interconnected porous structure, N, P-GDs are uniformly dispersed. The as-prepared P-GDs/N-3DG material served as metal-free catalyst for oxygen reduction reaction (ORR) in an alkaline medium evaluated rotating ring-disk electrode. exhibits excellent ORR activity, which is comparable to that commercial...
Proteolytic targeting chimera (PROTAC) technology is a protein-blocking technique and induces antitumor effects, with potential advantages. However, its effect limited by insufficient distribution accumulation in tumors. Herein, transformable nanomedicine (dBET6@CFMPD) mitochondrial capacity designed constructed to combine PROTAC photodynamic therapy (PDT). In this work, we demonstrate that dBET6@CFMPD exhibits great biodistribution retention, can induce potent response suppress primary...
The mechanistic aspects of the formation sulfobetaine-stabilized copper nanoparticles were investigated by using in situ XANES (X-ray absorption near edge structure), UV−vis spectroscopy, and reaction calorimetry. tetracoordinated sulfobetaine−Cu(II) complex was reduced to a stable sulfobetaine−Cu(I) prior nanoparticles. stability Cu(I) found be sensitive concentration sulfobetaine stabilizer addition rate reducing agent. It appears exist primarily as linear complex. A an intermediate has...
Abstract The active aromatic polyamide layers of thin film composite nanofiltration (NF‐TFC) membranes were prepared via interfacial polymerization (IP) from three different types polyamine: p ‐phenylenediamine (PPD), m (MPD), or piperazine (PRP), and trimesoyl chloride (TMC) on polysulfone/sulfonated polysulfone (PSf/SPSf) alloy substrates. Chemical components, cross section structures, thermal properties the bulk membranes, characterized by Fourier transfer IR spectroscopy attenuated total...
β-sitosterol (BS), a major bioactive constituent present in plants, has shown potent anti-cancer activity against many human cancer cells, but its pancreatic (PC) cells rarely been reported. Gemcitabine (GEM) is one of the first-line drugs for PC therapy, however, treatment effect not sustained due to prolonged drug resistance. In this study, we firstly studied anti-PC and mechanism BS alone combination with GEM vitro vivo . effectively inhibited growth cell lines by inhibiting...
The controlled synthesis of nanoparticles (NPs) with stable crystal structures and physical chemical properties is a key issue for commercial applications. use microfluidic reactor (MR) process has proven to be flexible approach control the fine magnetic during ripening aging NPs. We have developed an in situ rapidly cooling (IRCMP) which Co NPs are synthesized by using elevated reaction temperatures followed rapid quenching colloids reduced temperatures. that obtained this demonstrate much...
Co@Au core shell nanoparticles (NPs) of different thicknesses were fabricated by a combination the displacement process and reduction–deposition in microfluidic reactor. Changes sizes whole these NPs with formation investigated. Effects thickness size change on Co–Au interface pinning effects interparticle interaction analyzed correlated to their magnetic properties surface plasmon resonance (SPR). Increasing causes an increase coercivity at 10 K due enhanced interfacial pining effect...
Abstract Aqueous‐phase Fe 3 O 4 nanoparticles (NPs), with a size of 9.8 ± 3.0 nm, are directly synthesized by modified iron salt coprecipitation process, stabilized the synergistic effect combination poly(vinylpyrrolidone) (PVP), trisodium citrate (TSC), and maleic anhydride (MAH). These NPs show good aqueous‐phase dispersion stability excellent superparamagnetic properties saturation magnetization 48.0 emu/g at low magnetic field 0.5 T. Their biocompatibility metabolism for application in...