Alba Sierra

ORCID: 0000-0003-2474-8067
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About
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Research Areas
  • Kidney Stones and Urolithiasis Treatments
  • Pediatric Urology and Nephrology Studies
  • Ureteral procedures and complications
  • Renal and Vascular Pathologies
  • Urinary Bladder and Prostate Research
  • Bladder and Urothelial Cancer Treatments
  • Organ Donation and Transplantation
  • Radiation Dose and Imaging
  • Solid State Laser Technologies
  • Laser Applications in Dentistry and Medicine
  • Urological Disorders and Treatments
  • Diversity and Career in Medicine
  • Long-Term Effects of COVID-19
  • Laser Design and Applications
  • Intraocular Surgery and Lenses
  • Healthcare cost, quality, practices
  • COVID-19 Clinical Research Studies
  • SARS-CoV-2 and COVID-19 Research
  • Renal Transplantation Outcomes and Treatments
  • Renal cell carcinoma treatment
  • Social Media in Health Education
  • Medical Malpractice and Liability Issues
  • Patient-Provider Communication in Healthcare
  • Central Venous Catheters and Hemodialysis
  • Urinary and Genital Oncology Studies

Hospital Clínic de Barcelona
2011-2025

European Association of Urology
2023-2025

Hôpital Tenon
2021-2024

Sorbonne Université
2021-2024

Universitat de Barcelona
2021-2024

Hospital de Sant Pau
2023

Assistance Publique – Hôpitaux de Paris
2021-2023

Arts et Métiers
2022

ParisTech
2022

Centre National de la Recherche Scientifique
2022

No effective treatments for coronavirus disease 2019 (COVID-19) exist. We aimed to determine whether early treatment with hydroxychloroquine (HCQ) would be efficacious outpatients COVID-19.Multicenter open-label, randomized, controlled trial conducted in Catalonia, Spain, between 17 March and 26 May 2020. Patients recently diagnosed <5-day of symptom onset were assigned receive HCQ (800 mg on day 1 followed by 400 once daily 6 days) or usual care. Outcomes reduction viral load nasopharyngeal...

10.1093/cid/ciaa1009 article EN other-oa Clinical Infectious Diseases 2020-07-13

BackgroundCurrent strategies for preventing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection are limited to nonpharmacologic interventions. Hydroxychloroquine has been proposed as a postexposure therapy prevent disease 2019 (Covid-19), but definitive evidence is lacking.MethodsWe conducted an open-label, cluster-randomized trial involving asymptomatic contacts of patients with polymerase-chain-reaction (PCR)–confirmed Covid-19 in Catalonia, Spain. We randomly assigned...

10.1056/nejmoa2021801 article EN New England Journal of Medicine 2020-11-24

Objective: To evaluate using an inanimate model the thermal injury and laser efficiency on high frequency, energy, its combination in hands of junior experienced urologists during holmium YAG (Ho:YAG) Thulium fiber (TFL) lithotripsy. Methods: A Cyber: Ho 150 WTM Fiber Dust TFL (Quanta System) with 200 μm core-diameter fibers (LF) were used a saline vitro ureteral model. Each participant (five five urologists) performed 32 sessions 5-minute lasering (125 mm3 phantom BegoStones™), comparing...

10.1089/end.2022.0216 article EN Journal of Endourology 2022-07-06

(1) Objective: To support the efficacy and safety of a range thulium fiber laser (TFL) pre-set parameters for lithotripsy: efficiency is compared against Holmium:YAG (Ho:YAG) in hands juniors experienced urologists using an vitro ureteral model; damage both lasers evaluated vivo porcine model. (2) Materials Methods: Ho:YAG technology TFL technology, with 200 µm core-diameter fibers saline model were used. Each participant performed 12 sessions. session included 3-min lasering stone phantoms...

10.3390/jcm12010149 article EN Journal of Clinical Medicine 2022-12-24

(1) Introduction: To evaluate the feasibility of measuring intrapelvic pressure (IPP) during flexible ureterorenoscopy (f-URS) with a PressureWire and to optimize safety by assessing IPP surgery. (2) Methods: Patients undergoing f-URS for different treatments were recruited. A (0.014", St. Jude Medical, Little Canada, MN, USA) was placed into renal cavities measure IPP. Gravity irrigation at 40 cmH2O over patient hand-assisted system used. Pressures monitored in real time recorded analysis....

10.3390/jcm12010147 article EN Journal of Clinical Medicine 2022-12-24

ABSTRACT Background Current strategies for preventing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections are limited to non-pharmacological interventions. Hydroxychloroquine (HCQ) has been proposed as a postexposure therapy prevent Coronavirus disease 2019 (Covid-19) but definitive evidence is lacking. Methods We conducted an open-label, cluster-randomized trial including asymptomatic contacts exposed PCR-positive Covid-19 case in Catalonia, Spain. Clusters were...

10.1101/2020.07.20.20157651 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2020-07-26

10.1016/j.euros.2022.05.020 article EN cc-by-nc-nd European Urology Open Science 2022-08-19

Abstract Purpose To evaluate whether stone dust can be obtained from all prevailing composition types using the novel pulsed thulium:YAG (p-Tm:YAG), including analysis of particle size after lithotripsy. Methods Human urinary stones 7 different compositions were subjected to in vitro lithotripsy a p-Tm:YAG laser with 270 µm silica core fibers (Thulio ® , Dornier MedTech GmbH Wessling, Germany). A cumulative energy 1000 J was applied each one three settings: 0.1 × 100 Hz, 0.4 25 Hz and 2.0 5...

10.1007/s00345-023-04549-y article EN cc-by World Journal of Urology 2023-08-16

Abstract Purpose Artifacts from poor ureteroscopes’ light design with shadowing and dark areas in the field of view have been reported. The aim was to quantify effects obstruction a kidney calyx model. Methods We evaluated series contemporary flexible ureteroscopes including Storz Flex-Xc Flex-X2s, Olympus V3 P7, Pusen 7.5F 9.2F, as well OTU Wiscope using an enclosed 3D-printed pink vitro model submerged saline, where intentionally partially obstructed alternatively at 12, 3, 6, 9 o’clock. A...

10.1007/s00345-024-04910-9 article EN cc-by World Journal of Urology 2024-03-23

Illumination characteristics of flexible ureteroscopes have been evaluated in air, but not saline, the native operative medium for endourology. The aim was to evaluate light properties contemporary air versus distribution analysis, and color temperature.

10.1007/s00345-024-05037-7 article EN cc-by World Journal of Urology 2024-05-26

Background and Objective: The cost of imaging interventions in the surgical field varies between countries sometimes within different regions same country. Procedural takes into account equipment, consumables, operating room, surgical, anesthetic nursing teams, radiology, medications, hospital stay. Health care systems therefore face an incredible burden related to investigations procedures. aim this study was collect costs for kidney calculi across hospitals health world. Methods: An online...

10.1089/end.2024.0673 article EN Journal of Endourology 2025-02-28
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