A5012187278- Protein purification and stability
- Analytical Chemistry and Chromatography
- Microfluidic and Capillary Electrophoresis Applications
- Freezing and Crystallization Processes
- Fluid Dynamics and Mixing
- Viral Infectious Diseases and Gene Expression in Insects
- Textile materials and evaluations
- Mechanical and Thermal Properties Analysis
Polytechnic University of Turin
2018-2022
Chromatography is a technique widely used in the purification of biopharmaceuticals, and generally consists several chromatographic steps. In this work, Hydrophobic Interaction (HIC) investigated as polishing step for therapeutic proteins. Adsorption mechanisms hydrophobic interaction chromatography are still not completely clear limited amount published data available. addition to new on adsorption isotherms some proteins (obtained both by high-throughput frontal analysis method),...
Chromatography is a widely used separation process for purification of biopharmaceuticals that able to obtain high purities and concentrations. The phenomena occur during separation, mass transfer adsorption are quite complex. To better understand these their mechanisms, multi-component isotherms must be investigated. High-throughput methodologies very powerful tool determine they waste small amounts sample chemicals, but the quantification component concentrations real bottleneck in...