- Anaerobic Digestion and Biogas Production
- Biofuel production and bioconversion
- Microbial Metabolic Engineering and Bioproduction
- Photosynthetic Processes and Mechanisms
- Microbial bioremediation and biosurfactants
- Algal biology and biofuel production
- Microbial Fuel Cells and Bioremediation
- Bacteriophages and microbial interactions
- Methane Hydrates and Related Phenomena
- Microbial metabolism and enzyme function
- Microbial Community Ecology and Physiology
- Barrier Structure and Function Studies
- Genomics and Phylogenetic Studies
- Antimicrobial Peptides and Activities
- Drug Transport and Resistance Mechanisms
- biodegradable polymer synthesis and properties
- Plant Virus Research Studies
- Photoreceptor and optogenetics research
- Wastewater Treatment and Nitrogen Removal
- Metalloenzymes and iron-sulfur proteins
- Microbial infections and disease research
- Spectroscopy and Quantum Chemical Studies
- Electrochemical sensors and biosensors
- Pharmaceutical and Antibiotic Environmental Impacts
- Pesticide and Herbicide Environmental Studies
HUN-REN Szegedi Biológiai Kutatóközpont
2015-2024
Institute of Biophysics
2015-2024
University of Szeged
2015-2024
Hungarian Research Network
2021-2024
Hungarian Academy of Sciences
2010-2021
Czech Academy of Sciences, Institute of Biophysics
2011
Russian Academy of Sciences
2005
Abstract Background Renewable energy production is currently a major issue worldwide. Biogas promising renewable carrier as the technology of its combines elimination organic waste with formation versatile carrier, methane. In consequence complexity microbial communities and metabolic pathways involved biotechnology microbiological process leading to biogas poorly understood. Metagenomic approaches are suitable means addressing related questions. present work novel high-throughput technique...
Abstract Environmental biotechnology offers several promising techniques for the rehabilitation of polluted environments. The modern industrialized world presents novel challenges to environmental sciences, requiring a constant development and deepening knowledge enable characterization pollutants better understanding bioremediation strategies as well their limiting factors. success depends heavily on survival activities indigenous microbial communities interaction with introduced...
Stress is well known to contribute the development of both neurological and psychiatric diseases. While role blood-brain barrier increasingly recognised in neurodegenerative disorders, such as Alzheimer's disease, dysfunction has been linked stress-related diseases only recently. In present study effects restraint stress with different duration (1, 3 21 days) were investigated on morphology male adult Wistar rats. Frontal cortex hippocampus sections immunostained for markers brain...
It is generally accepted as a fact in the biogas technology that protein-rich biomass substrates should be avoided due to inevitable process inhibition. Substrate compositions with low C/N ratio are considered difficult handle and may lead failure, though industrial waste products have outstanding generation potential. This common belief has been challenged by using substrates, i.e. casein precipitated pig blood protein laboratory scale continuously stirred mesophilic fed-batch fermenters....
Cell culture-based blood-brain barrier (BBB) models are useful tools for screening of CNS drug candidates. sources BBB include primary brain endothelial cells or immortalized cell lines. Despite their well-known differences, epithelial lines also used as surrogate testing neuropharmaceuticals. The aim the present study was to compare expression selected related genes including tight junction proteins, solute carriers (SLC), ABC transporters, metabolic enzymes and describe paracellular...
Chronic pollution by used lubricant oils (ULOs) poses a serious challenge to the environment. Under stress conditions, microorganisms, including potential degraders, can enter viable but non-culturable (VBNC) state, complicating bioremediation of ULO-polluted areas. Resuscitation-promoting factors (Rpfs) reverse this transition and/or enhance biodegradation performance both native and augmented strains. Here, Rpf-containing extracellular organic matter (EOM) from Micrococcus luteus was ex...
Photobiological H2 production has the potential of becoming a carbon-free renewable energy source, because upon combustion H2, only water is produced. The [Fe–Fe]-type hydrogenases green algae are highly active, although extremely O2-sensitive. Sulphur deprivation common way to induce production, which, however, relies substantially on organic substrates and imposes severe stress effect resulting in degradation photosynthetic apparatus. We report establishment an alternative method by that...
Applications of the power-to-gas principle for handling surplus renewable electricity have been proposed. The feasibility using hydrogenotrophic methanogens as CH4 generating catalysts has demonstrated. Laboratory and scale-up experiments corroborated benefits CO2 mitigation via biotechnological conversion H2 to CH4. A major bottleneck in process is gas–liquid mass transfer H2. Fed-batch reactor configuration was tested at mesophilic temperature laboratory order improve contact time between...
This study demonstrates that appropriate adaptation of the microbial community to protein-rich biomass can lead sustainable biogas production. The process acclimation these unusual mono-substrates was controlled by protease activity community. Meat extract (C/N = 3.32) and kitchen waste 12.43) were used as substrates. Metagenome analysis highlighted several mesophilic strains displayed a preference for protein degradation. Bacillus coagulans, subtilis Pseudomonas fluorescens chosen detailed...
The cow rumen harbors a great variety of diverse microbes, which form complex, organized community. Understanding the behavior this multifarious network is crucial in improving ruminant nutrient use efficiency. aim study was to expand our knowledge by examining 10 Holstein dairy fluid fraction whole metagenome and transcriptome datasets. DNA mRNA sequence data, generated Ion Torrent, subjected quality control filtering before analysis for core elements. taxonomic microbiome consisted 48...
The growing concern regarding the use of agricultural land for production biomass food/feed or energy is dictating search alternative sources. Photosynthetic microorganisms grown on marginal deserted present a promising to cultivation plants and thereby may dampen 'food fuel' dispute. Microalgae offer diverse utilization routes.
Abstract The increasing incidence of carbapenemase-producing K. pneumoniae strains (CP-Kps) in the last decade has become a serious global healthcare problem. Therapeutic options for treatment emerging hospital clones have drastically narrowed and therefore novel approaches must be considered. Here we isolated characterized lytic bacteriophage, named vB_KpnS_Kp13, that was effective against all Verona integron-encoded metallo-β-lactamase (VIM) producing isolates originating from samples...
The rate-limiting nature of the hydrogen concentration prevailing in anaerobic digester has been recognized, but associated alterations microbial community are unknown. In response to addition Enterobacter cloacae cells laboratory digesters, level biogas production was augmented. Terminal restriction fragment length polymorphism (T-RFLP) and real-time polymerase chain reaction (Real-Time PCR) were used study survival mesophilic hydrogen-producing bacteria effects their presence on...
Summary Sulphur limitation may restrain cell growth and viability. In the green alga Chlamydomonas reinhardtii , sulphur induce H 2 production lasting for several days, which can be exploited as a renewable energy source. causes large number of physiological changes, including inactivation photosystem II ( PSII ), leading to establishment hypoxia, essential increase in hydrogenase expression activity. The has long been assumed caused by sulphur‐limited turnover its reaction center protein...