Hessam H. Kashani

ORCID: 0000-0003-2581-1769
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About
Contact & Profiles
Research Areas
  • Anesthesia and Sedative Agents
  • Cardiac Arrest and Resuscitation
  • Cardiac, Anesthesia and Surgical Outcomes
  • Autophagy in Disease and Therapy
  • Endoplasmic Reticulum Stress and Disease
  • Intensive Care Unit Cognitive Disorders
  • Menstrual Health and Disorders
  • Calpain Protease Function and Regulation
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Mechanical Circulatory Support Devices
  • Liver Disease Diagnosis and Treatment
  • Migraine and Headache Studies
  • Neonatal Respiratory Health Research
  • Acne and Rosacea Treatments and Effects
  • Hemodynamic Monitoring and Therapy
  • Acute Myocardial Infarction Research
  • Central Venous Catheters and Hemodialysis
  • Anesthesia and Neurotoxicity Research
  • Cardiac Fibrosis and Remodeling
  • Mesenchymal stem cell research
  • Dysphagia Assessment and Management
  • SARS-CoV-2 and COVID-19 Research
  • Long-Term Effects of COVID-19
  • Antimicrobial Resistance in Staphylococcus
  • Blood transfusion and management

University of Manitoba
2012-2024

Victoria General Hospital
2022

St. Boniface Hospital
2020-2022

Health Sciences Centre
2021-2022

George & Fay Yee Centre for Healthcare Innovation
2017-2019

Children's Hospital Research Institute of Manitoba
2011-2014

University of Gothenburg
2013

Research Manitoba
2011-2012

Aja University of Medical Sciences
2010

Isfahan University of Medical Sciences
2007-2009

3-hydroxy-3-methyl-glutaryl-CoA reductase inhibitors (statins) are cholesterol-lowering drugs that exert other cellular effects and underlie their beneficial health effects, including those associated with myocardial remodeling. We recently demonstrated statins induces apoptosis autophagy in human lung mesenchymal cells. Here, we extend our knowledge showing simultaneously activation of the apoptosis, unfolded protein response (UPR) primary atrial fibroblasts (hATF). Thus tested degree to...

10.1038/cddis.2012.61 article EN cc-by Cell Death and Disease 2012-06-21

Statins inhibit the proximal steps of cholesterol biosynthesis, and are linked to health benefits in various conditions, including cancer lung disease. We have previously investigated apoptotic pathways triggered by statins airway mesenchymal cells, identified reduced prenylation small GTPases as a primary effector mechanism leading p53-mediated cell death. Here, we extend our studies statin-induced death assessing endpoints both apoptosis autophagy, investigating their interplay coincident...

10.1371/journal.pone.0016523 article EN cc-by PLoS ONE 2011-01-31

Background : There is considerable evidence which suggests a possible pathogenetic role for Staphylococcus aureus (S. aureus) in acne vulgaris. Aim The study was to determine S. colonization and antibiotic susceptibility patterns patients with of healthy people. Materials Methods In the case-control study, total 324 people were screened nasal carriage aureus: 166 158 persons. One control subject individually matched one case. Nasal swabs from anterior nares individuals cultured identified as...

10.4103/1947-2714.103317 article EN North American Journal of Medical Sciences 2012-01-01
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