A5037794847- Microbial Inactivation Methods
- Composite Structure Analysis and Optimization
- Microfluidic and Bio-sensing Technologies
- Vibration and Dynamic Analysis
- Structural Analysis and Optimization
- Structural Load-Bearing Analysis
- 3D Printing in Biomedical Research
- Ion channel regulation and function
- Cardiac electrophysiology and arrhythmias
- Neuroscience and Neural Engineering
- Magnetic and Electromagnetic Effects
- Chemical Thermodynamics and Molecular Structure
- Reservoir Engineering and Simulation Methods
- Nanoplatforms for cancer theranostics
- Food Drying and Modeling
- Hydraulic Fracturing and Reservoir Analysis
- Plasma Applications and Diagnostics
- Mechanical and Thermal Properties Analysis
- Magnetic Bearings and Levitation Dynamics
- Neuroscience and Neuropharmacology Research
- Endodontics and Root Canal Treatments
- Chaos control and synchronization
- Composite Material Mechanics
- Cancer Cells and Metastasis
- Transgenic Plants and Applications
Virginia Tech
2011-2018
Virginia Tech - Wake Forest University School of Biomedical Engineering & Sciences
2016
Sharif University of Technology
2006-2008
University College London
1996-1997
University of London
1996-1997
Eastman Dental Hospital
1997
This device enables real-time monitoring of permeability across cell monolayers pre- and post-treatment by pulsed electric fields.
Purpose: This study evaluates the effects of active electrode cooling, via internal fluid circulation, on irreversible electroporation (IRE) lesion, deployed electric current and temperature changes using a perfused porcine liver model.Materials methods: A bipolar delivered IRE pulses with or without activation cooling to nine mechanically livers. Pulse schemes included constant voltage, preconditioned delivery combined an arc-mitigation algorithm. After treatment, organs were dissected,...
Our laboratory previously demonstrated that perfusate sodium and potassium concentrations can modulate cardiac conduction velocity (CV) consistent with theoretical predictions of ephaptic coupling (EpC). EpC depends on the ionic currents intercellular separation in channel rich intercalated disk microdomains like perinexus. We suggested perinexal width (WP) correlates changes extracellular calcium ([Ca(2+)]o). Here, we test hypothesis increasing [Ca(2+)]o reduces WP increases CV....
Irreversible electroporation (IRE) is gaining popularity as a focal ablation modality for the treatment of unresectable tumors. One clinical limitation IRE absence methods real-time evaluation, namely actively monitoring dimensions induced lesion. This information critical to ensure complete and minimize collateral damage surrounding healthy tissue.In this study, we are taking advantage biophysical properties living tissues address demand.Using advanced microfabrication techniques, have...
B lood vessel features in periodontal pocket soft tissues may be significant the pathogenesis and progression of chronic periodontitis. The aim this study was to make a quantitative histological assessment vasculature tissue biopsies from patients with adult periodontitis healthy tissues. We have also investigated changes morphology at both ultrastructural level. Twelve interdental were obtained, 6 volunteers. specimens sliced, fixed 3% glutaraldehyde, postfixed 1% buffered osmium tetroxide,...
Summary Viscosity of synthetic brines consisting sodium chloride, potassium chloride. and calcium chloride were measured at concentrations ranging from 0.99 to 16.667 wt% temperatures up 275 degrees C. From the use laboratory-derived data, a method is presented whereby viscosity geothermal brine may be estimated knowledge its composition. Introduction Many theoretical studies published on reservoir production characteristics liquid-dominated systems have used fluid properties representative...
When studying composite material systems, mechanical properties, such as stiffness, strength, fracture toughness or damage resistance are the subjects of greatest interest and in most cases considered context simple static loading conditions. However, almost all applications, composites, like materials subjected to dynamic which requires that response be analyzed. For structural linear elastic, stress-strain is not dependent on strain rate, there no hysteresis damping. this case for...
For viscoelastic materials the stiffness and loss properties directly depend on not only strain but also rate implicitly temperature via time superposition, which in case of harmonic loading leads to frequency dependent response.For composites at least one constituent is viscoelastic, there great utility ability predict effective dynamic mechanical as a function phase geometry.The presence different concentrations nanofillers impacts nanocomposite properties, contributes formation an...
A sixteen node cylindrical super element is presented for evaluating the free vibration characteristics of a rotating laminated cylinder with conventional boundary conditions. It shown that natural frequencies are affected considerably when centrifugal force also taken into account. The finite cylinder, obtained by used to evaluate accuracy this approach. special case stationary zero spinning velocity considered as check on method. Results indicate only few number elements capable predicting...
Functionally graded materials are advanced composite consisting two or more material ingredients that engineered to have a continuous spatial variation of properties. There few analytical methods available solve the governing equations FGM made structures, confined some specific and limited shapes, loadings boundary conditions. Hence numerical such as FEM used treat these materials. In previous studies finite element method was thin walled FG structures like shells plates by modification...
Irreversible electroporation (IRE) is a technique to kill cells by delivering series of short-duration, high voltage square wave electric pulses into tissue alter the native cellular transmembrane potential, creating irrecoverable nanoscale defects in cell membrane. IRE protocols constrain Joule heating below temperatures that cause coagulation extracellular proteins, and consequently spare critical structures contraindicate other thermal-based therapies. Tissue-level characterization...